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Author Details

Kari M Morrissey
Amunix Pharmaceuticals
2006
23
16
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36997747Precision-activated T-cell engagers targeting HER2 or EGFR and CD3 mitigate on-target, off-tumor toxicity for immunotherapy in solid tumors.Nat Cancer2023
30973970Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor.Br J Clin Pharmacol2019
29985971Computational analysis of kinase inhibitor selectivity using structural knowledge.Bioinformatics2019
31542806Alternative dosing regimens for atezolizumab: an example of model-informed drug development in the postmarketing setting.Cancer Chemother Pharmacol2019
29921320Phase Ia study of the indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor navoximod (GDC-0919) in patients with recurrent advanced solid tumors.J Immunother Cancer2018
30185228A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer.Breast Cancer Res2018
28664655Commentary on: "Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-Glucuronide".Clin Transl Sci2017
28992562A phase IB dose-escalation study of the safety and pharmacokinetics of pictilisib in combination with either paclitaxel and carboplatin (with or without bevacizumab) or pemetrexed and cisplatin (with or without bevacizumab) in patients with advanced non-small cell lung cancer.Eur J Cancer2017
28748626Combining "Bottom-up" and "Top-down" Approaches to Assess the Impact of Food and Gastric pH on Pictilisib (GDC-0941) Pharmacokinetics.CPT Pharmacometrics Syst Pharmacol2017
26924066Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities.Clin Transl Sci2016
26507723The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers.Clin Pharmacokinet2016
24961373OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.Proc Natl Acad Sci U S A2014
25275310Genome-wide discovery of drug-dependent human liver regulatory elements.PLoS Genet2014
23140242Renal transporters in drug development.Annu Rev Pharmacol Toxicol2013
23241029Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.J Med Chem2013
23267855The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin.Clin Pharmacol Ther2013
21383772Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.Pharmacogenomics J2012
23085876The UCSF-FDA TransPortal: a public drug transporter database.Clin Pharmacol Ther2012
21070833Consequences of POR mutations and polymorphisms.Mol Cell Endocrinol2011
21956618A common 5'-UTR variant in MATE2-K is associated with poor response to metformin.Clin Pharmacol Ther2011
20940534Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro.Pharmacogenet Genomics2010
18669588Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction.Drug Metab Dispos2008
16643277Expanding the role of the dynein regulatory complex to non-axonemal functions: association of GAS11 with the Golgi apparatus.Traffic2006
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