Skip to Main Content

Author Details

Nicolas L Young
Baylor College of Medicine, USA Center for Precision Environmental Health
2006
57
25
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35277331Histone variant-specific post-translational modifications.Semin Cell Dev Biol2023
37204295An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability.Elife2023
36754872Histone H4 proteoforms and post-translational modifications in the Mus musculus brain with quantitative comparison of ages and brain regions.Anal Bioanal Chem2023
35489683High-throughput profiling of histone post-translational modifications and chromatin modifying proteins by reverse phase protein array.J Proteomics2022
33441849Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery.Sci Rep2021
33492339Mechanistic insights into KDM4A driven genomic instability.Biochem Soc Trans2021
33567070Combinations of histone post-translational modifications.Biochem J2021
33647457Gene therapy using Aβ variants for amyloid reduction.Mol Ther2021
33534192Expeditious Extraction of Histones from Limited Cells or Tissue Samples and Quantitative Top-Down Proteomic Analysis.Curr Protoc2021
34242617The histone H3.3 chaperone HIRA restrains erythroid-biased differentiation of adult hematopoietic stem cells.Stem Cell Reports2021
32503840Characterization of SETD3 methyltransferase-mediated protein methionine methylation.J Biol Chem2020
32817218Orsay Virus CP-δ Adopts a Novel β-Bracelet Structural Fold and Incorporates into Virions as a Head Fiber.J Virol2020
32812765Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.J Am Soc Mass Spectrom2020
31147891One-Pot Quantitative Top- and Middle-Down Analysis of GluC-Digested Histone H4.J Am Soc Mass Spectrom2019
31697807AMP-activated protein kinase links acetyl-CoA homeostasis to BRD4 recruitment in acute myeloid leukemia.Blood2019
31741267High-Throughput Quantitative Top-Down Proteomics: Histone H4.J Am Soc Mass Spectrom2019
29443976How many human proteoforms are there?Nat Chem Biol2018
29940793Early butyrate induced acetylation of histone H4 is proteoform specific and linked to methylation state.Epigenetics2018
29880017The histone H4 proteoform dynamics in response to SUV4-20 inhibition reveals single molecule mechanisms of inhibitor resistance.Epigenetics Chromatin2018
30199238Control of Hexamerization, Assembly, and Excluded Strand Specificity for the Sulfolobus solfataricus MCM Helicase.Biochemistry2018
29667342Middle-Down Characterization of the Cell Cycle Dependence of Histone H4 Posttranslational Modifications and Proteoforms.Proteomics2018
27813191Ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometry and tandem mass spectrometry for peptide de novo amino acid sequencing for a seven-protein mixture by paired single-residue transposed Lys-N and Lys-C digestion.Rapid Commun Mass Spectrom2017
28241071Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells.PLoS Pathog2017
28797100Mapping the contact surfaces in the Lamin A:AIMP3 complex by hydrogen/deuterium exchange FT-ICR mass spectrometry.PLoS One2017
26209608Quantitative Mass Spectrometry Reveals that Intact Histone H1 Phosphorylations are Variant Specific and Exhibit Single Molecule Hierarchical Dependence.Mol Cell Proteomics2016
27431976Label-Free Relative Quantitation of Isobaric and Isomeric Human Histone H2A and H2B Variants by Fourier Transform Ion Cyclotron Resonance Top-Down MS/MS.J Proteome Res2016
27044751DNA Interactions Probed by Hydrogen-Deuterium Exchange (HDX) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Confirm External Binding Sites on the Minichromosomal Maintenance (MCM) Helicase.J Biol Chem2016
26169135Epitope mapping of 7S cashew antigen in complex with antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry.J Mass Spectrom2015
26212284Paired single residue-transposed Lys-N and Lys-C digestions for label-free identification of N-terminal and C-terminal MS/MS peptide product ions: ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry and tandem mass spectrometry for peptide de novo sequencing.Rapid Commun Mass Spectrom2015
26088143The N-terminal Domain of Escherichia coli Assimilatory NADPH-Sulfite Reductase Hemoprotein Is an Oligomerization Domain That Mediates Holoenzyme Assembly.J Biol Chem2015
24212136Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction.Nat Chem Biol2014
24644084The first pilot project of the consortium for top-down proteomics: a status report.Proteomics2014
24723542Ultraviolet photodissociation enhances top-down mass spectrometry as demonstrated on green fluorescent protein variants.Proteomics2014
24496597Protected amine labels: a versatile molecular scaffold for multiplexed nominal mass and sub-Da isotopologue quantitative proteomic reagents.J Am Soc Mass Spectrom2014
23409238Nucleotide-induced conformational changes of tetradecameric GroEL mapped by H/D exchange monitored by FT-ICR mass spectrometry.Sci Rep2013
23945933H1 histones: current perspectives and challenges.Nucleic Acids Res2013
23681851Rapid screening for potential epitopes reactive with a polycolonal antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry.J Am Soc Mass Spectrom2013
22343720Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses.Nat Struct Mol Biol2012
23021224Asymmetrically modified nucleosomes.Cell2012
22722849SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.Nature2012
21708950Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity.J Biol Chem2011
21774791Methylation of H2AR29 is a novel repressive PRMT6 target.Epigenetics Chromatin2011
21966350Quantitative proteomic approaches to studying histone modifications.Curr Chem Genomics2011
21935452Proteomic interrogation of human chromatin.PLoS One2011
20103568A novel approach for untargeted post-translational modification identification using integer linear optimization and tandem mass spectrometry.Mol Cell Proteomics2010
20683756The significance, development and progress of high-throughput combinatorial histone code analysis.Cell Mol Life Sci2010
20577673Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown.Mol Biosyst2010
20121478Systems-wide proteomic characterization of combinatorial post-translational modification patterns.Expert Rev Proteomics2010
20202861Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a.J Am Soc Mass Spectrom2010
19250903Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.Mol Cell2009
  • 1 - 50 of 57

Recommended Authors

Jacek W Sikora
and the Feinberg School of Medicine, Northwestern University
Career Start Year 2018
Number of shared co-authors 11
Anthony J Cesnik
University of Wisconsin-Madison
Career Start Year 2015
Number of shared co-authors 22
Caroline J DeHart
Frederick National Laboratory for Cancer Research
Career Start Year 2013
Number of shared co-authors 23
Dennis Goldfarb
Washington University School of Medicine
Career Start Year 2012
Number of shared co-authors 2
Jeannie M Camarillo
and the Feinberg School of Medicine, Northwestern University
Career Start Year 2011
Number of shared co-authors 11
Yael David
Tri-Institutional PhD Program in Chemical Biology
Career Start Year 2010
Number of shared co-authors 2
Scott B Rothbart
Van Andel Institute
Career Start Year 2009
Number of shared co-authors 5
Yansheng Liu
Yale University School of Medicine
Career Start Year 2008
Number of shared co-authors 6
Danielle L Swaney
J. David Gladstone Institutes
Career Start Year 2007
Number of shared co-authors 3
Edward L Huttlin
Harvard Medical School
Career Start Year 2006
Number of shared co-authors 2
Douglas H Phanstiel
University of North Carolina at Chapel Hill
Career Start Year 2006
Number of shared co-authors 2
Georg Kustatscher
University of Edinburgh
Career Start Year 2005
Number of shared co-authors 1
Lihua Jiang
Stanford University
Career Start Year 2004
Number of shared co-authors 5
Patrick G A Pedrioli
Institute of Translational Medicine, Swiss Federal Institute of Technology/ETH Zurich
Career Start Year 2004
Number of shared co-authors 4
Feng Yang
Howard Hughes Medical Institute, University of California San Diego
Career Start Year 2003
Number of shared co-authors 9
Chunaram Choudhary
The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Career Start Year 2003
Number of shared co-authors 2
Veit Schw??mmle
University of Southern Denmark
Career Start Year 2003
Number of shared co-authors 14
Ludovic Gillet
ETH Zurich
Career Start Year 2002
Number of shared co-authors 2
Jeroen A A Demmers
Erasmus Medical Center
Career Start Year 2000
Number of shared co-authors 1
Fran??ois-Michel Boisvert
Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)
Career Start Year 1999
Number of shared co-authors 2
Juri Rappsilber
Institute for Biotechnology, Technical University Berlin
Career Start Year 1998
Number of shared co-authors 10
Ragna Sack
Friedrich Miescher Institute for Biomedical Research
Career Start Year 1997
Number of shared co-authors 0
Mark Scalf
University of Wisconsin-Madison College of Letters and Sciences
Career Start Year 1997
Number of shared co-authors 4
Albert J R Heck
Utrecht University
Career Start Year 1991
Number of shared co-authors 13
Steven P Gygi
Harvard Medical School
Career Start Year 1991
Number of shared co-authors 16
Karl Mechtler
IMP-Institute of Molecular Pathology
Career Start Year 1990
Number of shared co-authors 9
Matthias Mann
Max-Planck Institute of Biochemistry
Career Start Year 1989
Number of shared co-authors 17
David Feny??
Institute for Systems Genetics, NYU Grossman School of Medicine
Career Start Year 1989
Number of shared co-authors 16
Birgit Schilling
Buck Institute for Research on Aging
Career Start Year 1985
Number of shared co-authors 9
Steven A Carr
Broad Institute of MIT and Harvard
Career Start Year 1980
Number of shared co-authors 15

Collaborators

Benjamin A Garcia
University of Pennsylvania
Co-authored papers 19
Gary LeRoy
Co-authored papers 6
Neil L Kelleher
Northwestern University
Co-authored papers 3
Jeffrey N Agar
Northeastern University
Co-authored papers 3
Wendy Sandoval
Genentech Inc.
Co-authored papers 2
Or Gozani
Stanford University
Co-authored papers 2
Joseph A Loo
University of California los angeles
Co-authored papers 2
Ying Ge
University of Wisconsin-Madison
Co-authored papers 2
Ljiljana Pa??a-Toli??
Pacific Northwest National Laboratory
Co-authored papers 2
Paul M Thomas
Northwestern University
Co-authored papers 2
Lloyd M Smith
University of Wisconsin-Madison College of Letters and Sciences
Co-authored papers 2
Christopher L Hendrickson
Florida State University
Co-authored papers 1
Vamsi K Mootha
Broad Institute of MIT and Harvard
Co-authored papers 1
James J Pesavento
Saint Mary's College of California
Co-authored papers 1
Julia Chamot-Rooke
Institut Pasteur, Universite Paris Cite, CNRS UAR4
Co-authored papers 1
Paul O Danis
Co-authored papers 1
Kevin Struhl
Co-authored papers 1
Amander T Clark
Center for Reproductive Science, University of California los angeles
Co-authored papers 1
Steven M Patrie
Northwestern University
Co-authored papers 1
Therese Wohlschlager
University of Salzburg
Co-authored papers 1
Brian D Strahl
University of North Carolina
Co-authored papers 1
Michael C Jewett
Northwestern University
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Wei Li
Co-authored papers 1
Sung Yun Jung
Co-authored papers 1
Jin Young Lee
Samsung Medical Center, College of Medicine, The Sungkyunkwan University of Korea
Co-authored papers 1
Carolyn R Bertozzi
Stanford University
Co-authored papers 1
Ole N Jensen
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 1
Mark S Baker
Macquarie University
Co-authored papers 1
Rupa Sridharan
Wisconsin Institute for Discovery, University of Wisconsin-Madison
Co-authored papers 1
Release 1.2