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Author Details

Susan C Fagan
Charlie Norwood Veterans Affairs Medical Center
1984
183
53
PMIDPaper TitleJournal TitlePublished Year
36563009Deferoxamine prevents poststroke memory impairment in female diabetic rats: potential links to hemorrhagic transformation and ferroptosis.Am J Physiol Heart Circ Physiol2023
37374057Stimulation of Angiotensin II Type 2 Receptor Modulates Pro-Inflammatory Response in Microglia and Macrophages: Therapeutic Implications for the Treatment of Stroke.Life (Basel)2023
37065376Myocarditis as a Complication of Campylobacter jejuni-Associated Enterocolitis: A Report of Two Cases.Cureus2023
35688299Contralesional angiotensin type 2 receptor activation contributes to recovery in experimental stroke.Neurochem Int2022
32875455Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis.Transl Stroke Res2021
33572986Delayed Administration of Angiotensin Receptor (AT2R) Agonist C21 Improves Survival and Preserves Sensorimotor Outcomes in Female Diabetic Rats Post-Stroke through Modulation of Microglial Activation.Int J Mol Sci2021
34481068Stimulation of angiotensin II receptor 2 preserves cognitive function and is associated with an enhanced cerebral vascular density after stroke.Vascul Pharmacol2021
34831161Neuroprotective Effects of Fingolimod in a Cellular Model of Optic Neuritis.Cells2021
33954091Overview and Update on Methods for Cargo Loading into Extracellular Vesicles.Processes (Basel)2021
32345303Microglia knockdown reduces inflammation and preserves cognition in diabetic animals after experimental stroke.J Neuroinflammation2020
31792796Delayed Administration of Angiotensin II Type 2 Receptor (AT2R) Agonist Compound 21 Prevents the Development of Post-stroke Cognitive Impairment in Diabetes Through the Modulation of Microglia Polarization.Transl Stroke Res2020
33214598Stroke promotes the development of brain atrophy and delayed cell death in hypertensive rats.Sci Rep2020
29537907Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke.J Cereb Blood Flow Metab2019
30243988Post-stroke neovascularization and functional outcomes differ in diabetes depending on severity of injury and sex: Potential link to hemorrhagic transformation.Exp Neurol2019
31315064Inflammation within the neurovascular unit: Focus on microglia for stroke injury and recovery.Pharmacol Res2019
31098864Neuropsychiatric Symptoms in Dementia: Considerations for Pharmacotherapy in the USA.Drugs R D2019
30822121Angiotensin II type 2 receptor stimulation with compound 21 improves neurological function after stroke in female rats: a pilot study.Am J Physiol Heart Circ Physiol2019
30818045NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia.Pharmacol Res2019
30816798Brain Vasculature and Cognition.Arterioscler Thromb Vasc Biol2019
30296528Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals-A randomized double- blind pre-clinical study.Behav Brain Res2019
28975464Peroxynitrite-Induced Tyrosine Nitration Contributes to Matrix Metalloprotease-3 Activation: Relevance to Hyperglycemic Ischemic Brain Injury and Tissue Plasminogen Activator.Neurochem Res2018
38089216Medicine Pharmacy Interprofessional Exercise Pilot: Lessons Learned.MedEdPublish (2016)2018
30103772RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial.J Neuroinflammation2018
30118341Poststroke cognitive impairment and hippocampal neurovascular remodeling: the impact of diabetes and sex.Am J Physiol Heart Circ Physiol2018
30088238Silencing VEGF-B Diminishes the Neuroprotective Effect of Candesartan Treatment After Experimental Focal Cerebral Ischemia.Neurochem Res2018
29543776Within the Brain: The Renin Angiotensin System.Int J Mol Sci2018
29229547Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals - A randomized double- blind pre-clinical study.Behav Brain Res2018
26758277Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke.Mol Neurobiol2017
28192099Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury.Eur J Pharmacol2017
28247188Diabetes Worsens Functional Outcomes in Young Female Rats: Comparison of Stroke Models, Tissue Plasminogen Activator Effects, and Sexes.Transl Stroke Res2017
28640888Mechanisms of acute neurovascular protection with AT1 blockade after stroke: Effect of prestroke hypertension.PLoS One2017
28887388Minocycline in Acute Cerebral Hemorrhage: An Early Phase Randomized Trial.Stroke2017
26839355Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke.Stroke2016
27482214ARBs improve stroke outcome through an AT2-dependent, BDNF-induced proangiogenic and prorecovery response.Neural Regen Res2016
27303620Erratum to: Artery reopening is required for the neurorestorative effects of angiotensin modulation after experimental stroke.Exp Transl Stroke Med2016
27558234Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle.Life Sci2016
27127602Artery reopening is required for the neurorestorative effects of angiotensin modulation after experimental stroke.Exp Transl Stroke Med2016
26769658Renin-angiotensin system as a potential therapeutic target in stroke and retinopathy: experimental and clinical evidence.Clin Sci (Lond)2016
27026092Impact of Comorbidities on Acute Injury and Recovery in Preclinical Stroke Research: Focus on Hypertension and Diabetes.Transl Stroke Res2016
24939693Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.Mol Neurobiol2015
26317114Vascular protective effects of Angiotensin Receptor Blockers: Beyond Blood pressure.Receptors Clin Investig2015
26033700The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis.Br J Pharmacol2015
26004281Sequential Therapy with Minocycline and Candesartan Improves Long-Term Recovery After Experimental Stroke.Transl Stroke Res2015
25683354Comparative Analysis of Different Methods of Ischemia/Reperfusion in Hyperglycemic Stroke Outcomes: Interaction with tPA.Transl Stroke Res2015
25754657Vascular protection with dipeptidyl peptidase-IV inhibitors in diabetes: experimental and clinical therapeutics.Pharmacotherapy2015
25749094Cellular connections, microenvironment and brain angiogenesis in diabetes: Lost communication signals in the post-stroke period.Brain Res2015
25502293Erratum to: Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.Mol Neurobiol2015
25420481Candesartan stimulates reparative angiogenesis in ischemic retinopathy model: role of hemeoxygenase-1 (HO-1).Angiogenesis2015
25552308SOD1 overexpression prevents acute hyperglycemia-induced cerebral myogenic dysfunction: relevance to contralateral hemisphere and stroke outcomes.Am J Physiol Heart Circ Physiol2015
25524911Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes.Diabetes2015
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Collaborators

State University of New York Downstate Health Sciences University
Co-authored papers 10
Pennsylvania State University, University Park
Co-authored papers 4
University of Texas Health Science Center, School of Public Health at Houston
Co-authored papers 4
University of Cincinnati College of Medicine
Co-authored papers 4
Mayo Clinic
Co-authored papers 4
University of Washington
Co-authored papers 2
University of Cincinnati Gardner Neuroscience Institute, University of Cincinnati
Co-authored papers 2
UT Southwestern Medical Center
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
University of California san francisco
Co-authored papers 2
University of Pennsylvania School of Medicine
Co-authored papers 1
University of California Los Angeles (D.S.L.).
Co-authored papers 1
Duke University
Co-authored papers 1
Dent Neurologic Institute
Co-authored papers 1
College of Medicine, University of Cincinnati
Co-authored papers 1
Alpert Medical School of Brown University
Co-authored papers 1
David Geffen School of Medicine, University of California, Los Angeles Medical Center
Co-authored papers 1
University of North Carolina Health Sciences at Mountain Area Health Education Center
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
Christchurch Hospital
Co-authored papers 1
Johns Hopkins University School of Medicine
Co-authored papers 1
University of Georgia College of Pharmacy
Co-authored papers 1
Ronald Reagan university of california los angeles Medical Center
Co-authored papers 1
Henry Ford Hospital
Co-authored papers 1
Wake Forest School of Medicine
Co-authored papers 1
National Institute of Neurological Disorders and Stroke
Co-authored papers 1