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Author Details

Edyta Malolepsza
Broad Institute of MIT and Harvard
2005
26
13
PMIDPaper TitleJournal TitlePublished Year
36621880Returning integrated genomic risk and clinical recommendations: The eMERGE study.Genet Med2023
37207277Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.iScience2023
34849650Endothelial ARHGEF26 is an angiogenic factor promoting VEGF signalling.Cardiovasc Res2022
35710995Genome-wide polygenic score to predict chronic kidney disease across ancestries.Nat Med2022
35765100Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.Genome Med2022
35595084Multiancestral polygenic risk score for pediatric asthma.J Allergy Clin Immunol2022
33351783Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML.JCI Insight2021
33790022Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.Sci Transl Med2021
34568833<i>ZBTB33</i> is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing.Blood Cancer Discov2021
33972534Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data.Nat Commun2021
32325033BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.Cell Syst2020
32853540BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.Cell Syst2020
29955178Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.Nat Genet2018
25337983Role of Charge and Solvation in the Structure and Dynamics of Alanine-Rich Peptide AKA2 in AOT Reverse Micelles.J Phys Chem B2015
26624929Pathways through Equilibrated States with Coexisting Phases for Gas Hydrate Formation.J Phys Chem B2015
26398582Isobaric Molecular Dynamics Version of the Generalized Replica Exchange Method (gREM): Liquid-Vapor Equilibrium.J Phys Chem B2015
26642983Water Freezing and Ice Melting.J Chem Theory Comput2015
25978217Entropic Description of Gas Hydrate Ice-Liquid Equilibrium via Enhanced Sampling of Coexisting Phases.Phys Rev Lett2015
24654732Empirical maps for the calculation of amide I vibrational spectra of proteins from classical molecular dynamics simulations.J Phys Chem B2014
25494801Exploring the role of hydration and confinement in the aggregation of amyloidogenic peptides Aβ(16-22) and Sup35(7-13) in AOT reverse micelles.J Chem Phys2014
23687916Probing the structure and dynamics of confined water in AOT reverse micelles.J Phys Chem B2013
22432601Dynamics of methionine ligand rebinding in cytochrome c.J Phys Chem B2012
20082393Symmetrization of the AMBER and CHARMM force fields.J Comput Chem2010
18446294Modeling of protein misfolding in disease.Methods Mol Biol2008
17429953Comparison of geometric, electronic, and vibrational properties for isomers of small fullerenes C20-C36.J Phys Chem A2007
15911770Theoretical model of prion propagation: a misfolded protein induces misfolding.Proc Natl Acad Sci U S A2005
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Collaborators

Kasper Lage
Co-authored papers 8
Steven A Carr
Broad Institute of MIT and Harvard
Co-authored papers 5
Jordan W Smoller
Center for Genomic Medicine, Massachusetts General Hospital
Co-authored papers 4
Krzysztof Kiryluk
Columbia University
Co-authored papers 4
Gail P Jarvik
University of Washington Medical Center
Co-authored papers 4
Iftikhar J Kullo
Mayo Clinic
Co-authored papers 4
Elizabeth W Karlson
Brigham and Women's Hospital
Co-authored papers 3
Niall J Lennon
Broad Institute of MIT and Harvard.
Co-authored papers 3
Kalliopi Tsafou
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard
Co-authored papers 3
Daniel J Schaid
Mayo Clinic
Co-authored papers 3
Bahram Namjou
Cincinnati Children's Hospital
Co-authored papers 3
Nita A Limdi
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 3
Hemant K Tiwari
University of Alabama at Birmingham
Co-authored papers 3
Marguerite R Irvin
University of Alabama at Birmingham School of Public Health
Co-authored papers 3
Leah C Kottyan
Cincinnati Children's Hospital Medical Center
Co-authored papers 3
Eimear E Kenny
Icahn School of Medicine at Mount Sinai, NY Institute for Genomic Health
Co-authored papers 3
Ramy H Malty
University of Toronto, University of Regina
Co-authored papers 2
Wei-Qi Wei
Vanderbilt University Medical Center
Co-authored papers 2
Frank D Mentch
Center for Applied Genomics (CAG), Children's Hospital of Philadelphia
Co-authored papers 2
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 2
Elisabeth A Rosenthal
University of Washington Medical Center
Co-authored papers 2
Hongbo Guo
Beihang University
Co-authored papers 2
Wendy K Chung
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
Christoph Lange
Co-authored papers 2
Kevin Eggan
Co-authored papers 2
Shawn N Murphy
Harvard Medical School
Co-authored papers 2
Theresa L Walunas
Northwestern University Feinberg School of Medicine
Co-authored papers 2
Hailiang Huang
Massachusetts General Hospital
Co-authored papers 2
Cynthia A Prows
Cincinnati Children's Hospital Medical Center
Co-authored papers 2
Haiyuan Yu
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 2
Release 1.2