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Author Details

Cynthia A Bradham
Boston University
1995
52
28
PMIDPaper TitleJournal TitlePublished Year
36368523Ethanol exposure perturbs sea urchin development and disrupts developmental timing.Dev Biol2023
37086439ICAT: a novel algorithm to robustly identify cell states following perturbations in single-cell transcriptomes.Bioinformatics2023
36948411Polychrome labeling reveals skeletal triradiate and elongation dynamics and abnormalities in patterning cue-perturbed embryos.Dev Biol2023
37139779Voltage-gated sodium channel activity mediates sea urchin larval skeletal patterning through spatial regulation of Wnt5 expression.Development2023
34900995Derivedness Index for Estimating Degree of Phenotypic Evolution of Embryos: A Study of Comparative Transcriptomic Analyses of Chordates and Echinoderms.Front Cell Dev Biol2021
33824400Author Correction: Genomic insights of body plan transitions from bilateral to pentameral symmetry in Echinoderms.Commun Biol2021
31816285The developmental transcriptome for Lytechinus variegatus exhibits temporally punctuated gene expression changes.Dev Biol2020
30948024Spatially mapping gene expression in sea urchin primary mesenchyme cells.Methods Cell Biol2019
30948026Measuring voltage and ion concentrations in live embryos.Methods Cell Biol2019
26755701RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins.Development2016
26905309Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo.Dev Biol2016
25633352Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos.Development2015
26282894H(+)/K(+) ATPase activity is required for biomineralization in sea urchin embryos.Dev Biol2015
25167787A computational model for BMP movement in sea urchin embryos.J Theor Biol2014
23063796NF-κB is required for cnidocyte development in the sea anemone Nematostella vectensis.Dev Biol2013
22431628Pantropic retroviruses as a transduction tool for sea urchin embryos.Proc Natl Acad Sci U S A2012
21387455Mitochondrial gradients and p38 activity in early sea urchin embryos.Mol Reprod Dev2011
19389361Chordin is required for neural but not axial development in sea urchin embryos.Dev Biol2009
16319119p38 MAPK is essential for secondary axis specification and patterning in sea urchin embryos.Development2006
17078944The genomic repertoire for cell cycle control and DNA metabolism in S. purpuratus.Dev Biol2006
17095691The genome of the sea urchin Strongylocentrotus purpuratus.Science2006
17027740The sea urchin kinome: a first look.Dev Biol2006
17054939A functional genomic and proteomic perspective of sea urchin calcium signaling and egg activation.Dev Biol2006
17084834RTK and TGF-beta signaling pathways genes in the sea urchin genome.Dev Biol2006
16959243Translational control genes in the sea urchin genome.Dev Biol2006
16627995p38 MAPK in development and cancer.Cell Cycle2006
15042695PI3K inhibitors block skeletogenesis but not patterning in sea urchin embryos.Dev Dyn2004
12668975c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration.Hepatology2003
11804847Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha.Am J Physiol Gastrointest Liver Physiol2002
12143039Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells.Hepatology2002
11668037Dominant-negative TAK1 induces c-Myc and G(0) exit in liver.Am J Physiol Gastrointest Liver Physiol2001
11679966TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells.Hepatology2001
10752746Gene expression and cytokine and enzyme activation in the liver after a burn injury.J Burn Care Rehabil2000
10899173The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.J Biol Chem2000
10766806The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes.J Biol Chem2000
10477620Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity.J Immunol1999
10989668Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death.Biochem Soc Symp1999
10388501Activation of nuclear factor-kappaB during orthotopic liver transplantation in rats is protective and does not require Kupffer cells.Liver Transpl Surg1999
10665521Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death.J Bioenerg Biomembr1999
10051475Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of Kupffer cells.Hepatology1999
10201981TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells.J Immunol1999
10545411Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms.Carcinogenesis1999
9714796The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy.Biochim Biophys Acta1998
9914830Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy.Biofactors1998
9774651The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release.Mol Cell Biol1998
9724248Mechanisms of hepatic toxicity. I. TNF-induced liver injury.Am J Physiol1998
9357820Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation.Am J Physiol1997
9141429Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases.Hepatology1997
8643674Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function.Proc Natl Acad Sci U S A1996
8944691Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo.Am J Physiol1996
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Collaborators

Co-authored papers 21
Duke University
Co-authored papers 7
Max-Planck-Institut fur Molekulare Genetik
Co-authored papers 5
CNRS, Sorbonne Universite
Co-authored papers 4
Western Michigan University
Co-authored papers 4
Brown University
Co-authored papers 4
Institut Biology Valrose, Universite Cote d'Azur
Co-authored papers 3
Sorbonne Universite, CNRS
Co-authored papers 3
CNRS, Sorbonne Universite
Co-authored papers 3
California State University
Co-authored papers 3
Present address: King Abdullah University of Science and Technology
Co-authored papers 3
Universite Cote d'Azur, CNRS, Inserm
Co-authored papers 3
Universite Paris Cite, CNRS
Co-authored papers 3
St. Petersburg College
Co-authored papers 3
Duke University Medical Center
Co-authored papers 3
University of Maine
Co-authored papers 3
Sorbonne Universites, France CNRS
Co-authored papers 3
California State University
Co-authored papers 3
Sorbonne Universite, CNRS
Co-authored papers 3
University of New Orleans
Co-authored papers 3
Cellular and Developmental Biology and Marine Science Institute
Co-authored papers 3
Auburn University
Co-authored papers 2
Scripps Institution of Oceanography, University of California
Co-authored papers 2
Universite Cote d'Azur-CNRS-Inserm-Institute for Research on Cancer and Ageing
Co-authored papers 2
Cardiovascular Research Institute, University of California san francisco
Co-authored papers 2
Complex Systems Institute Paris Ile-de-France (ISC-PIF, CNRS
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
National Science Foundation
Co-authored papers 2
University of California berkeley
Co-authored papers 2