Author details

Full Name

Diane L Barber

Affiliation

University of California San Francisco

ORCID

Career Start Year

1986

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35658973	Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification.	Stem Cell Reports	2022
33237838	pHLARE: a new biosensor reveals decreased lysosome pH in cancer cells.	Mol Biol Cell	2021
34038242	Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells.	Am J Physiol Cell Physiol	2021
34143606	Low pH Facilitates Heterodimerization of Mutant Isocitrate Dehydrogenase IDH1-R132H and Promotes Production of 2-Hydroxyglutarate.	Biochemistry	2021
32983969	Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective.	Front Oncol	2020
32791470	Editorial overview: Cell dynamics: Integrating cell dynamics across scales.	Curr Opin Cell Biol	2020
32729927	An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity.	Biochem J	2020
30992364	Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH.	J Biol Chem	2019
30982102	Intracellular pH dynamics and charge-changing somatic mutations in cancer.	Cancer Metastasis Rev	2019
29668357	Formin-dependent TGF-Î² signaling for epithelial to mesenchymal transition.	Mol Biol Cell	2018
30315137	Î²-Catenin is a pH sensor with decreased stability at higher intracellular pH.	J Cell Biol	2018
28874603	Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins.	Sci Signal	2017
28202602	Cancer cell behaviors mediated by dysregulated pH dynamics at a glance.	J Cell Sci	2017
29158350	Cell fate decisions: emerging roles for metabolic signals and cell morphology.	EMBO Rep	2017
28952923	A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.	Elife	2017
28837668	Prominent features of the amino acid mutation landscape in cancer.	PLoS One	2017
28646105	The glycolytic enzyme phosphofructokinase-1 assembles into filaments.	J Cell Biol	2017
27650500	A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity.	J Biol Chem	2016
27821494	Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation.	J Cell Biol	2016
25601402	The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit.	J Cell Biol	2015
25985179	Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.	Nature	2015
25616899	Hypoxia increases the abundance but not the assembly of extracellular fibronectin during epithelial cell transdifferentiation.	J Cell Sci	2015
25793441	Increased Hâº efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.	Elife	2015
24974041	Ratiometric imaging of pH probes.	Methods Cell Biol	2014
28898680	Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.	Cancer Cell	2014
25446897	Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.	Cancer Cell	2014
23223240	Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium.	J Biol Chem	2013
24043700	pH sensing by FAK-His58 regulates focal adhesion remodeling.	J Cell Biol	2013
23451893	Considering protonation as a posttranslational modification regulating protein structure and function.	Annu Rev Biophys	2013
23486468	Electrostatics control actin filament nucleation and elongation kinetics.	J Biol Chem	2013
22731252	Characterization of cytoskeletal protein 4.1R interaction with NHE1 (Na(+)/H(+) exchanger isoform 1).	Biochem J	2012
21833026	Dysregulated pH: a perfect storm for cancer progression.	Nat Rev Cancer	2011
22031288	Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.	Mol Biol Cell	2011
22125478	Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation.	PLoS Comput Biol	2011
20668166	Expression of actin-interacting protein 1 suppresses impaired chemotaxis of Dictyostelium cells lacking the Na+-H+ exchanger NHE1.	Mol Biol Cell	2010
20720019	Nuclear-localized calcineurin homologous protein CHP1 interacts with upstream binding factor and inhibits ribosomal RNA synthesis.	J Biol Chem	2010
20936779	A human MAP kinase interactome.	Nat Methods	2010
19225158	Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation.	Mol Biol Cell	2009
19622752	The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors.	J Biol Chem	2009
19029335	Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding.	J Cell Biol	2008
19066573	Actin co-sedimentation assay; for the analysis of protein binding to F-actin.	J Vis Exp	2008
18780792	Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling.	Proc Natl Acad Sci U S A	2008
18725535	Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments.	J Cell Biol	2008
17289928	Intracellular pH sensors: design principles and functional significance.	Physiology (Bethesda)	2007
17984318	Positive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cells.	J Cell Biol	2007
17565280	Beyond ion translocation: structural functions of the sodium-hydrogen exchanger isoform-1.	Curr Opin Nephrol Hypertens	2007
16938849	The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors.	Proc Natl Acad Sci U S A	2006
15851518	A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis.	J Cell Biol	2005
15355855	Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes.	Am J Physiol Cell Physiol	2004
15257760	Expression profile of genes regulated by activity of the Na-H exchanger NHE1.	BMC Genomics	2004

1 - 50 of 83

Florent Dingli

Institut Curie, PSL Research University

Career Start Year 2011

Number of shared co-authors 0

Hyun Woo Park

College of Life Science and Biotechnology, Yonsei University

Career Start Year 2006

Number of shared co-authors 0

Erin D Jeffery

Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia

Career Start Year 2005

Number of shared co-authors 0

Kui Zhai

Lerner Research Institute, Cleveland Clinic

Career Start Year 2005

Number of shared co-authors 0

Ana Velic

Interfaculty Institute for Cell Biology.

Career Start Year 2003

Number of shared co-authors 0

Dana-Lynn T Koomoa

University of Hawai'i at Hilo

Career Start Year 2001

Number of shared co-authors 0

Jayantha Gunaratne

Institute of Molecular and Cell Biology

Career Start Year 2000

Number of shared co-authors 0

Gregory A Gibson

University of Pittsburgh

Career Start Year 1999

Number of shared co-authors 1

Ashok K Pullikuth

Wake Forest University School of Medicine

Career Start Year 1997

Number of shared co-authors 0

Robert Grosse

University of Freiburg

Career Start Year 1996

Number of shared co-authors 2

Damarys Loew

Institut Curie, PSL Research University

Career Start Year 1996

Number of shared co-authors 0

Clara E Magyar

David Geffen School of Medicine, University of California at Los Angeles

Career Start Year 1994

Number of shared co-authors 0

Karen H Martin

West Virginia University Cancer Institute, West Virginia University

Career Start Year 1993

Number of shared co-authors 0

Jiefei Tong

Hospital for Sick Children

Career Start Year 1993

Number of shared co-authors 0

Hjalmar Brismar

Royal Institute of Technology, Karolinska Institutet

Career Start Year 1992

Number of shared co-authors 0

Donna J Webb

Vanderbilt University

Career Start Year 1991

Number of shared co-authors 0

Andrea Hellwig

Interdisciplinary Center for Neurosciences (IZN), University of Heidelberg

Career Start Year 1991

Number of shared co-authors 0

Kun-Liang Guan

University of California San Diego

Career Start Year 1988

Number of shared co-authors 0

David A Eberhard

Lineberger Comprehensive Cancer Center, University of North Carolina

Career Start Year 1987

Number of shared co-authors 0

S??ren P Sheikh

Odense University Hospital

Career Start Year 1985

Number of shared co-authors 2

Michael F Moran

Hospital for Sick Children, University of Toronto

Career Start Year 1985

Number of shared co-authors 0

Jorge Silvio Gutkind

Moores Cancer Center, University of California San Diego

Career Start Year 1984

Number of shared co-authors 4

Daniela Rotin

The Hospital for Sick Children

Career Start Year 1982

Number of shared co-authors 0

Sylvain Meloche

Institute for Research in Immunology and Cancer

Career Start Year 1982

Number of shared co-authors 0

Simon C Watkins

Center for Molecular Imaging, University of Pittsburgh School of Medicine

Career Start Year 1981

Number of shared co-authors 2

Seth L Alper

Beth Israel Deaconess Medical Center RN380F

Career Start Year 1978

Number of shared co-authors 0

Ravi Iyengar

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Career Start Year 1976

Number of shared co-authors 0

Mark Donowitz

Johns Hopkins University School of Medicine

Career Start Year 1974

Number of shared co-authors 0

Karin D Rodland

Oregon Health and Science University

Career Start Year 1973

Number of shared co-authors 0

Jonathan M Backer

Albert Einstein College of Medicine

Career Start Year 1970

Number of shared co-authors 0

row(s) 1 - 30 of 30

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 10

Jyoti Srivastava

Moffitt Cancer Center

Co-authored papers 8

Torsten Wittmann

University of California san francisco

Co-authored papers 4

Diego Garrido Ruiz

Department of Pharmaceutical Chemistry, University of California at San Francisco

Co-authored papers 2

Laura J Van't Veer

University of California San Francisco

Co-authored papers 2

Ryan D Hernandez

University of California san francisco

Co-authored papers 2

Denise M Wolf

University of California San Francisco

Co-authored papers 2

Zachary A Szpiech

Pennsylvania State University

Co-authored papers 2

Mark J S Kelly

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 2

Jennifer Haynes

Joan C. Edwards School of Medicine, Marshall University

Co-authored papers 1

Suhaila White

The Salk Institute

Co-authored papers 1

Angela Cacace

O.W.) and University of Rochester Medical Center

Co-authored papers 1

Sourav Bandyopadhyay

University of California San Francisco

Co-authored papers 1

Olivier Lichtarge

Baylor College of Medicine

Co-authored papers 1

Bruce R Conklin

Gladstone Institutes

Co-authored papers 1

Russell Bell

Huntsman Cancer Institute at the University of Utah

Co-authored papers 1

Sudhir Sahasrabudhe

University of Medicine and Dentistry of New Jersey, New Jersey Medical School

Co-authored papers 1

R Dyche Mullins

University of California San Francisco, USA Howard Hughes Medical Institute

Co-authored papers 1

Michael Smoot

University of California

Co-authored papers 1

Jonathan A Pachter

Laufer Center for Physical and Quantitative Biology, Stony Brook University

Co-authored papers 1

Chih-Yuan Chiang

United States Army Medical Research Institute of Infectious Diseases

Co-authored papers 1

Christopher Martin

Co-authored papers 1

Justin M Kollman

University of Washington

Co-authored papers 1

Merril Gersten

University of California

Co-authored papers 1

Sagar Manoli

University of California san francisco

Co-authored papers 1

John Kuriyan

University of California berkeley

Co-authored papers 1

David A Scott

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 1

Henry R Bourne

Co-authored papers 1

Cornelia Kurschner

Saint Jude Children's Research Hospital

Co-authored papers 1

Trey Ideker (CM4AI)

University of California San Diego

Co-authored papers 1

1 - 30

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