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Author Details
Full Name
Patrick Aloy
Affiliation
Institucio Catalana de Recerca i Estudis Avancats (ICREA)
ORCID
Career Start Year
1997
Papers
138
H Index
48
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36217029
A proteome-scale map of the SARS-CoV-2-human contactome.
Nat Biotechnol
2023
37821946
Global analysis of suppressor mutations that rescue human genetic defects.
Genome Med
2023
37725353
BQsupports: systematic assessment of the support and novelty of new biomedical associations.
Bioinformatics
2023
37337100
Democratizing knowledge representation with BioCypher.
Nat Biotechnol
2023
36894123
Characterization of p38α Signaling Networks in Cancer Cells Using Quantitative Proteomics and Phosphoproteomics.
Mol Cell Proteomics
2023
34626922
Connecting chemistry and biology through molecular descriptors.
Curr Opin Chem Biol
2022
35540106
Molecular characterization of chronic liver disease dynamics: From liver fibrosis to acute-on-chronic liver failure.
JHEP Rep
2022
36085310
Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque.
Nat Commun
2022
35106508
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.
Cell Rep Med
2022
34358215
Association of Transcriptomic Signatures of Inflammatory Response with Viral Control after Dendritic Cell-Based Therapeutic Vaccination in HIV-1 Infected Individuals.
Vaccines (Basel)
2021
33677561
Analysing the yeast complexome-the Complex Portal rising to the challenge.
Nucleic Acids Res
2021
34702310
Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in App<sup>NL-G-F</sup>, App<sup>NL-F</sup>, and 3xTg-AD mouse models.
Genome Med
2021
34042294
Natural variants suppress mutations in hundreds of essential genes.
Mol Syst Biol
2021
33958448
Environmental robustness of the global yeast genetic interaction network.
Science
2021
34168145
Bioactivity descriptors for uncharacterized chemical compounds.
Nat Commun
2021
32296183
A reference map of the human binary protein interactome.
Nature
2020
31904703
A Classifier to Predict Viral Control After Antiretroviral Treatment Interruption in Chronic HIV-1-Infected Patients.
J Acquir Immune Defic Syndr
2020
32064787
Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability.
Mol Syst Biol
2020
32939983
Systematic analysis of bypass suppression of essential genes.
Mol Syst Biol
2020
32907621
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.
Genome Med
2020
32672454
Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs.
J Chem Inf Model
2020
32440005
Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker.
Nat Biotechnol
2020
32440008
Publisher Correction: Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker.
Nat Biotechnol
2020
30971948
<i>In silico</i> Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.
Front Physiol
2019
31803016
DYRK1A Overexpression Alters Cognition and Neural-Related Proteomic Pathways in the Hippocampus That Are Rescued by Green Tea Extract and/or Environmental Enrichment.
Front Mol Neurosci
2019
32128329
Virological Outcome Measures During Analytical Treatment Interruptions in Chronic HIV-1-Infected Patients.
Open Forum Infect Dis
2019
31094488
Truncating variant burden in high-functioning autism and pleiotropic effects of LRP1 across psychiatric phenotypes
J Psychiatry Neurosci
2019
30914058
Encircling the regions of the pharmacogenomic landscape that determine drug response.
Genome Med
2019
29626539
Rationalizing Drug Response in Cancer Cell Lines.
J Mol Biol
2018
30071882
Exploring the OncoGenomic Landscape of cancer.
Genome Med
2018
30065243
Systems analysis of intracellular pH vulnerabilities for cancer therapy.
Nat Commun
2018
30275468
Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline.
Nat Commun
2018
30274705
DynBench3D, a Web-Resource to Dynamically Generate Benchmark Sets of Large Heteromeric Protein Complexes.
J Mol Biol
2018
29414760
Proteome Data Improves Protein Function Prediction in the Interactome of <i>Helicobacter pylori</i>.
Mol Cell Proteomics
2018
29749927
The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.
Elife
2018
27879272
Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.
Cancer Res
2017
28453651
A PanorOmic view of personal cancer genomes.
Nucleic Acids Res
2017
29269382
A framework for exhaustively mapping functional missense variants.
Mol Syst Biol
2017
28662117
Detecting similar binding pockets to enable systems polypharmacology.
PLoS Comput Biol
2017
26995226
Risk assessment of Soulatrolide and Mammea (A/BA+A/BB) coumarins from Calophyllum brasiliense by a toxicogenomic and toxicological approach.
Food Chem Toxicol
2016
27811238
Exploring genetic suppression interactions on a global scale.
Science
2016
27553366
Cancer network activity associated with therapeutic response and synergism.
Genome Med
2016
26807587
Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems.
PLoS One
2016
26688214
Residues Coevolution Guides the Systematic Identification of Alternative Functional Conformations in Proteins.
Structure
2016
26774489
Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli.
Cell Rep
2016
27107014
An inter-species protein-protein interaction network across vast evolutionary distance.
Mol Syst Biol
2016
27107012
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Mol Syst Biol
2016
26871637
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell
2016
25380960
IntSide: a web server for the chemical and biological examination of drug side effects.
Bioinformatics
2015
26549850
Isolation of Human Colon Stem Cells Using Surface Expression of PTK7.
Stem Cell Reports
2015
1 - 50 of 138
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