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Author Details

Bissan Al-Lazikani
The University of Texas MD Anderson Cancer Center
1997
63
34
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36268860The Chemical Probes Portal: an expert review-based public resource to empower chemical probe assessment, selection and use.Nucleic Acids Res2023
37602223SwarmDeepSurv: swarm intelligence advances deep survival network for prognostic radiomics signatures in four solid cancers.Patterns (N Y)2023
36624665canSAR: update to the cancer translational research and drug discovery knowledgebase.Nucleic Acids Res2023
35643512canSAR chemistry registration and standardization pipeline.J Cheminform2022
33300337Tuning Local Hydration Enables a Deeper Understanding of Protein-Ligand Binding: The PP1-Src Kinase Case.J Phys Chem Lett2021
33822745JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer.Cancer Res2021
35211674Target 2035 - update on the quest for a probe for every protein.RSC Med Chem2021
34077750Evolution of kinase polypharmacology across HSP90 drug discovery.Cell Chem Biol2021
31778323Public resources for chemical probes: the journey so far and the road ahead.Future Med Chem2021
33219674canSAR: update to the cancer translational research and drug discovery knowledgebase.Nucleic Acids Res2021
32994435Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches.Sci Rep2020
32066817The kinase polypharmacology landscape of clinical PARP inhibitors.Sci Rep2020
32094403Correction: Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.Oncogene2020
30496479canSAR: update to the cancer translational research and drug discovery knowledgebase.Nucleic Acids Res2019
31296956Signalling involving MET and FAK supports cell division independent of the activity of the cell cycle-regulating CDK4/6 kinases.Oncogene2019
31262731Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in <i>KRAS</i>-Mutant Cancers.Mol Cancer Ther2019
31543384A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations.Eur J Cancer2019
31284790Transforming cancer drug discovery with Big Data and AI.Expert Opin Drug Discov2019
29249694Objective, Quantitative, Data-Driven Assessment of Chemical Probes.Cell Chem Biol2018
30226926Genomics, bio specimens, and other biological data: Current status and future directions.Med Phys2018
30652614Leveraging Human Genetics to Guide Cancer Drug Development.JCO Clin Cancer Inform2018
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
27910877A comprehensive map of molecular drug targets.Nat Rev Drug Discov2017
28436422Rational design of non-resistant targeted cancer therapies.Sci Rep2017
28826504Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer.Elife2017
28545060SiGNet: A signaling network data simulator to enable signaling network inference.PLoS One2017
26947069Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.Cell Rep2016
26673713canSAR: an updated cancer research and drug discovery knowledgebase.Nucleic Acids Res2016
27669965Polypharmacology in Precision Oncology: Current Applications and Future Prospects.Curr Pharm Des2016
27580970Minimizing bias in target selection by exploiting multidisciplinary Big Data and the protein interactome.Future Med Chem2016
27444228Drug discovery in advanced prostate cancer: translating biology into therapy.Nat Rev Drug Discov2016
26820296Blocking the survival of the nastiest by HSP90 inhibition.Oncotarget2016
25709118Therapeutic opportunities within the DNA damage response.Nat Rev Cancer2015
26699810Distinctive Behaviors of Druggable Proteins in Cellular Networks.PLoS Comput Biol2015
23435416JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.Oncogene2014
24304894canSAR: updated cancer research and drug discovery knowledgebase.Nucleic Acids Res2014
23361103Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance.Clin Pharmacol Ther2013
24287764Drugging cancer genomes.Nat Rev Drug Discov2013
23810823Genome-based cancer therapeutics: targets, kinase drug resistance and future strategies for precision oncology.Curr Opin Pharmacol2013
23582742A novel serum protein signature associated with resistance to epidermal growth factor receptor tyrosine kinase inhibitors in head and neck squamous cell carcinoma.Eur J Cancer2013
23274470Objective assessment of cancer genes for drug discovery.Nat Rev Drug Discov2013
23319765Unpicking the combination lock for mutant BRAF and RAS melanomas.Cancer Discov2013
21948594ChEMBL: a large-scale bioactivity database for drug discovery.Nucleic Acids Res2012
22781697Combinatorial drug therapy for cancer in the post-genomic era.Nat Biotechnol2012
22516256Personalized medicine: patient-predictive panel power.Cancer Cell2012
22013161canSAR: an integrated cancer public translational research and drug discovery resource.Nucleic Acids Res2012
21632985A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma.Sci Transl Med2011
21936816Collation and data-mining of literature bioactivity data for drug discovery.Biochem Soc Trans2011
21878981Minimum information about a bioactive entity (MIABE).Nat Rev Drug Discov2011
20727982Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation.Drug Discov Today2010
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Collaborators

The Institute of Cancer Research
Co-authored papers 28
Institute of Cardiovascular Science, University College London
Co-authored papers 9
Wellcome Sanger Institute
Co-authored papers 7
The Institute for Cancer Research
Co-authored papers 6
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 4
University of Dundee
Co-authored papers 3
Columbia University Irving Medical Center
Co-authored papers 3
Co-authored papers 3
Institute of Integrative Biology, University of Liverpool
Co-authored papers 2
The Wellcome Trust Sanger Institute
Co-authored papers 2
University of Washington, USA Institute for Stem Cell and Regenerative Medicine
Co-authored papers 2
Wellcome Sanger Institute
Co-authored papers 2
The Institute of Cancer Research
Co-authored papers 2
The Institute for Cancer Research
Co-authored papers 2
Co-authored papers 2
University of Washington
Co-authored papers 1
University College London, Cancer Institute
Co-authored papers 1
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 1
The Institute of Cancer Research
Co-authored papers 1
Center for Emerging and Re-emerging Infectious Diseases, University of Washington
Co-authored papers 1
The Royal Marsden NHS Foundation Trust
Co-authored papers 1
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
University College London
Co-authored papers 1
Moores Cancer Center, university of california san diego
Co-authored papers 1
University of Oxford
Co-authored papers 1
The Royal Marsden NHS Foundation Trust and Institute of Cancer Research
Co-authored papers 1
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 1
UF Health Cancer Center
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Princess Margaret Cancer Centre, University Health Network
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