Author details

Full Name

Karen Sachs

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37161853	CD69 marks a subpopulation of acute myeloid leukemia with enhanced colony forming capacity and a unique signaling activation state.	Leuk Lymphoma	2023
37387179	Optimal adjustment sets for causal query estimation in partially observed biomolecular networks.	Bioinformatics	2023
35115730	Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.	Nat Neurosci	2022
35758817	Do-calculus enables estimation of causal effects in partially observed biomolecular pathways.	Bioinformatics	2022
36432424	Peripheral T-Cells, B-Cells, and Monocytes from Multiple Sclerosis Patients Supplemented with High-Dose Vitamin D Show Distinct Changes in Gene Expression Profiles.	Nutrients	2022
34469729	High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment.	Cell Rep	2021
31784425	Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia.	Cancer Res	2020
29199020	The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.	Cell Syst	2018
29927613	A Bayesian Active Learning Experimental Design for Inferring Signaling Networks.	J Comput Biol	2018
29850785	GateFinder: projection-based gating strategy optimization for flow and mass cytometry.	Bioinformatics	2018
27827829	Distinct signaling programs control human hematopoietic stem cell survival and proliferation.	Blood	2017
26731284	From Correlation to Causality: Statistical Approaches to Learning Regulatory Relationships in Large-Scale Biomolecular Investigations.	J Proteome Res	2016
25316678	NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia.	Blood	2014
24511382	Single timepoint models of dynamic systems.	Interface Focus	2013
23512433	Normalization of mass cytometry data with bead standards.	Cytometry A	2013
22902532	Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators.	Nat Biotechnol	2012
21551058	Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum.	Science	2011
21357764	Single-cell phospho-specific flow cytometric analysis demonstrates biochemical and functional heterogeneity in human hematopoietic stem and progenitor compartments.	Blood	2011
21964415	Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE.	Nat Biotechnol	2011
19963681	Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes.	Annu Int Conf IEEE Eng Med Biol Soc	2009
19209696	Learning cyclic signaling pathway structures while minimizing data requirements.	Pac Symp Biocomput	2009
19193145	Learning signaling network structures with sparsely distributed data.	J Comput Biol	2009
15845847	Causal protein-signaling networks derived from multiparameter single-cell data.	Science	2005
12209052	Bayesian network approach to cell signaling pathway modeling.	Sci STKE	2002