Author details

Full Name

Gerard D Schellenberg

Affiliation

ORCID

Career Start Year

1977

Papers

400

H Index

110

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37349795	A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.	Mol Neurodegener	2023
37745545	Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects.	medRxiv	2023
37693521	Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project.	medRxiv	2023
37390458	The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.	Alzheimers Dement	2023
37260021	Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.	Alzheimers Dement	2023
37051669	A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.	Alzheimers Dement	2023
36539198	Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.	Alzheimers Dement	2023
34873813	Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.	Alzheimers Dement	2022
35770850	Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.	Alzheimers Dement	2022
35379992	New insights into the genetic etiology of Alzheimer's disease and related dementias.	Nat Genet	2022
35552371	Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.	Brain	2022
35997131	Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.	Mov Disord	2022
35788729	A locus at 19q13.31 significantly reduces the ApoE Îµ4 risk for Alzheimer's Disease in African Ancestry.	PLoS Genet	2022
36411364	Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.	Nat Genet	2022
36846102	The role of structural variations in Alzheimer's disease and other neurodegenerative diseases.		2022
34152079	Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease.	Alzheimers Dement	2022
35258170	Progranulin mutations in clinical and neuropathological Alzheimer's disease.	Alzheimers Dement	2022
35210353	An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns.	Genome Res	2022
35142102	Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.	Alzheimers Dement	2022
35142023	Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE É¿2 for Alzheimer's disease.	Alzheimers Dement	2022
35156446	Genome-wide association study of brain arteriolosclerosis.	J Cereb Blood Flow Metab	2022
35068457	Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.	Journal of Alzheimer's Disease	2022
35005195	Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease.	Alzheimers Dement (Amst)	2021
33635380	Latent trait modeling of tau neuropathology in progressive supranuclear palsy.	Acta Neuropathol	2021
33897612	Gene-Environment Interactions in Progressive Supranuclear Palsy.	Front Neurol	2021
33385254	In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.	Acta Neuropathol	2021
34804120	Copy Number Variation Identification on 3,800 Alzheimer's Disease Whole Genome Sequencing Data from the Alzheimer's Disease Sequencing Project.	Frontiers in Genetics	2021
34739309	TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy.	Sci Adv	2021
32838419	Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo.	J Neuropathol Exp Neurol	2020
31911587	Transmission of tauopathy strains is independent of their isoform composition.	Nat Commun	2020
32426924	Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.	Alzheimers Dement	2020
32878640	Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.	Alzheimers Res Ther	2020
32591829	Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.	Brain	2020
32527607	LRP10 variants in progressive supranuclear palsy.	Neurobiol Aging	2020
32961270	Fibrillation and molecular characteristics are coherent with clinical and pathological features of 4-repeat tauopathy caused by MAPT variant G273R.	Neurobiol Dis	2020
32844198	Genetic variants and functional pathways associated with resilience to Alzheimer's disease.	Brain	2020
31426376	<i>APOE</i> Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of <i>APOE</i> Îµ4 on Alzheimer's Disease Risk in a Multiracial Sample.	J Clin Med	2019
31852801	Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.	Sci Transl Med	2019
31561366	Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants.	Journal of Alzheimer's Disease	2019
30503768	A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.	Alzheimers Dement	2019
30351394	VCPA: genomic variant calling pipeline and data management tool for Alzheimer's Disease Sequencing Project.		2019
29857119	Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.	Genomics	2019
30229991	Is APOE Îµ4 required for Alzheimer's disease to develop in TREM2 p.R47H variant carriers?	Neuropathology and Applied Neurobiology	2019
30413934	Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.	Acta Neuropathol	2019
31144443	CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.	Aging Cell	2019
30820047	Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates AÎ², tau, immunity and lipid processing.	Nat Genet	2019
30924900	Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.	JAMA Netw Open	2019
31180460	Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.	JAMA Neurol	2019
30689776	Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.	Brain	2019
31327044	C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.	Acta Neuropathol	2019