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Author Details

Daniel W McVicar
National Cancer Institute
1976
140
56
PMIDPaper TitleJournal TitlePublished Year
37066331Interferon-gamma is Quintessential for NOS2 and COX2 Expression in ER <sup>-</sup> Breast Tumors that Lead to Poor Outcome.bioRxiv2023
37940068Androgen receptor inhibition suppresses anti-tumor neutrophil response against bone metastatic prostate cancer via regulation of TβRI expression.Cancer Lett2023
37607904Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming.Nat Commun2023
37185821IFN-γ and androgens disrupt mitochondrial function in murine myocytes.J Pathol2023
37153622IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.Front Immunol2023
37308721Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice.Nat Metab2023
37169743Interferon-gamma is quintessential for NOS2 and COX2 expression in ER<sup>-</sup> breast tumors that lead to poor outcome.Cell Death Dis2023
35223446Tumor-Infiltrating Myeloid Cells Co-Express TREM1 and TREM2 and Elevated TREM-1 Associates With Disease Progression in Renal Cell Carcinoma.Front Oncol2022
35586249<i>Mycobacterium tuberculosis</i> Induces <i>Irg1</i> in Murine Macrophages by a Pathway Involving Both TLR-2 and STING/IFNAR Signaling and Requiring Bacterial Phagocytosis.Front Cell Infect Microbiol2022
36375380Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density.Redox Biol2022
34209132Nitric Oxide Modulates Metabolic Processes in the Tumor Immune Microenvironment.Int J Mol Sci2021
34642183Myeloid-Derived Suppressive Cell Expansion Promotes Melanoma Growth and Autoimmunity by Inhibiting CD40/IL27 Regulation in Macrophages.Cancer Res2021
34344832A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation.Sci Signal2021
32292401<i>TREML4</i> Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse.Front Immunol2020
32019928Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase.Nat Commun2020
31683257Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level.Redox Biol2020
33114647Nitric Oxide in Macrophage Immunometabolism: Hiding in Plain Sight.Metabolites2020
33194773Editorial: Metabolism Meets Function: Untangling the Cross-Talk Between Signaling and Metabolism.Front Oncol2020
32812866Metabolic but not transcriptional regulation by PKM2 is important for natural killer cell responses.Elife2020
29634348Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism.Antioxid Redox Signal2019
30152521Understanding the tumour micro-environment communication network from an NOS2/COX2 perspective.Br J Pharmacol2019
30247792Diversity and environmental adaptation of phagocytic cell metabolism.J Leukoc Biol2019
29329284Identification of an elaborate NK-specific system regulating HLA-C expression.PLoS Genet2018
29920191Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.J Clin Invest2018
30504842Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.Nat Commun2018
29784770TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation.Blood Adv2018
27494631Inducible Nitric Oxide Synthase in the Carcinogenesis of Gastrointestinal Cancers.Antioxid Redox Signal2017
28218747MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.Nat Struct Mol Biol2017
29234000Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels.Nat Commun2017
29087320Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.Proc Natl Acad Sci U S A2017
28813676Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.Cell Rep2017
27766406CD164 identifies CD4<sup>+</sup> T cells highly expressing genes associated with malignancy in Sézary syndrome: the Sézary signature genes, FCRL3, Tox, and miR-214.Arch Dermatol Res2017
27099176Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency.Sci Transl Med2016
26439909Interaction of a dengue virus NS1-derived peptide with the inhibitory receptor KIR3DL1 on natural killer cells.Clin Exp Immunol2016
27676159Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production.Redox Biol2016
27390655Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity.Springerplus2016
27467282Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression.Genes Immun2016
27045007Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.J Exp Med2016
26934227NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.Nature2016
25480565The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope.J Immunol2015
26494122Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.Cancer Res2015
26117324Signaling and stress: The redox landscape in NOS2 biology.Free Radic Biol Med2015
26089339Erratum for O'Connor et al., Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.J Virol2015
25867094Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo.Eur J Immunol2015
25740999Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1.J Virol2015
24563253Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity.J Immunol2014
25474109Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.PLoS One2014
24975946Integrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcification.Am J Hum Genet2014
23756244The yin-yang of KIR3DL1/S1: molecular mechanisms and cellular function.Crit Rev Immunol2013
23906311Environmental factors determine DAP12 deficiency to either enhance or suppress immunopathogenic processes.Immunology2013
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Collaborators

Stephen K Anderson
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 21
Laura Quigley
National Cancer Institute-Frederick
Co-authored papers 15
Erika M Palmieri
Center for Cancer Research
Co-authored papers 13
Mary Carrington
Frederick National Laboratory for Cancer Research, National Cancer Institute
Co-authored papers 12
John J O'Shea
National Institute of Arthritis, National Institutes of Health
Co-authored papers 12
Howard A Young
Center for Cancer Research, National Cancer Institute
Co-authored papers 7
Jami Willette-Brown
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
Randall Merchant
Virginia Commonwealth University
Co-authored papers 6
Marieli Gonzalez-Cotto
Center for Cancer Research
Co-authored papers 5
Kimberly C Boelte
National Cancer Institute
Co-authored papers 5
Douglas B Kuhns
Frederick National Laboratory for Cancer Research
Co-authored papers 5
Hongchuan Li
Frederick National Laboratory for Cancer Research
Co-authored papers 4
Tracey A Rouault
Co-authored papers 4
Shurjo K Sen
Louisiana State University
Co-authored papers 3
Edward M Schaeffer
Northwestern University Feinberg School of Medicine
Co-authored papers 3
Stephen M Hewitt
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
Galit Alter
Co-authored papers 3
Giorgio Trinchieri
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
Stephen T C Wong
Houston Methodist Research Institute
Co-authored papers 3
Marcus Altfeld
Co-authored papers 3
Jenny Chang-Claude
German Cancer Research Center (DKFZ)
Co-authored papers 3
William J Murphy
Co-authored papers 2
Jayanta Debnath
University of California San Francisco
Co-authored papers 2
Bruce D Walker
Ragon Institute of Mass General
Co-authored papers 2
Leslie G Biesecker
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 2
Jeffrey N Martin
Co-authored papers 2
S??bastien Gibot
Centre Hospitalier Regional Universitaire (CHRU)
Co-authored papers 2
Timothy R Billiar
University of Pittsburgh
Co-authored papers 2
Jennifer J Barb
Clinical Center, National Institutes of Health
Co-authored papers 2
Amalio Telenti
Vir Biotechnology Inc.
Co-authored papers 2
Release 1.2