Author details

Full Name

Richard E Pratt

Affiliation

ORCID

Career Start Year

1980

Papers

168

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36847443	Rig1 receptor plays a critical role in cardiac reprogramming via YY1 signaling.	Am J Physiol Cell Physiol	2023
36894665	Novel method of differentiating human induced pluripotent stem cells to mature cardiomyocytes via Sfrp2.	Sci Rep	2023
37044217	Neonatal and adult cardiac fibroblasts exhibit inherent differences in cardiac regenerative capacity.	J Biol Chem	2023
35605661	A novel Cbx1, PurB, and Sp3 complex mediates long-term silencing of tissue- and lineage-specific genes.	J Biol Chem	2022
34380738	A role for Sfrp2 in cardiomyogenesis in vivo.	Proc Natl Acad Sci U S A	2021
33813849	CRISPR/Cas9 Mediated Deletion of the Angiotensinogen Gene Reduces Hypertension: A Potential for Cure?	Hypertension	2021
33335792	Enhancing cardiac reprogramming via synthetic RNA oligonucleotides.	Mol Ther Nucleic Acids	2020
32917363	Optimizing delivery for efficient cardiac reprogramming.	Biochem Biophys Res Commun	2020
33026832	Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy.	Am J Physiol Cell Physiol	2020
29676038	Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B.	Stem Cells	2018
30171847	Insights from molecular signature of in vivo cardiac c-Kit(+) cells following cardiac injury and Î²-catenin inhibition.	J Mol Cell Cardiol	2018
28096202	HASF (C3orf58) is a novel ligand of the insulin-like growth factor 1 receptor.	Biochem J	2017
26595172	Nuclear hormone receptor LXRÎ± inhibits adipocyte differentiation of mesenchymal stem cells with Wnt/beta-catenin signaling.	Lab Invest	2016
26975336	Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.	Sci Rep	2016
27295344	Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling.	Lab Invest	2016
26071893	Inhibition of Wnt6 by Sfrp2 regulates adult cardiac progenitor cell differentiation by differential modulation of Wnt pathways.	J Mol Cell Cardiol	2015
25776075	Salt restriction leads to activation of adult renal mesenchymal stromal cell-like cells via prostaglandin E2 and E-prostanoid receptor 4.	Hypertension	2015
25351576	MicroRNA induced cardiac reprogramming in vivo: evidence for mature cardiac myocytes and improved cardiac function.	Circ Res	2015
26188399	Blockade of angiotensin II type 2 receptor by PD123319 inhibits osteogenic differentiation of human mesenchymal stem cells via inhibition of extracellular signal-regulated kinase signaling.	J Am Soc Hypertens	2015
24269490	HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection.	J Mol Cell Cardiol	2014
25296984	Abi3bp regulates cardiac progenitor cell proliferation and differentiation.	Circ Res	2014
23666637	Abi3bp is a multifunctional autocrine/paracrine factor that regulates mesenchymal stem cell biology.	Stem Cells	2013
23744888	Adult renal mesenchymal stem cell-like cells contribute to juxtaglomerular cell recruitment.	J Am Soc Nephrol	2013
20118482	Mesenchymal stem cells differentiate into renin-producing juxtaglomerular (JG)-like cells under the control of liver X receptor-alpha.	J Biol Chem	2010
21078975	Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.	Proc Natl Acad Sci U S A	2010
20378860	Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.	Circ Res	2010
19109969	Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a.	J Mol Cell Cardiol	2009
19353525	Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction.	Stem Cells	2009
17507648	Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment.	Mol Biol Cell	2007
20409848	Molecular mechanism of juxtaglomerular cell hyperplasia: a unifying hypothesis.	J Am Soc Hypertens	2007
16581974	Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement.	FASEB J	2006
16965940	Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation.	Mol Ther	2006
17060512	Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes.	Hypertension	2006
16449792	Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function.	FASEB J	2006
16835353	Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy.	Physiol Genomics	2006
16825578	Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium.	Circ Res	2006
16286588	Angiotensin type 2 receptor is expressed in murine atherosclerotic lesions and modulates lesion evolution.	Circulation	2005
15812508	Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.	Nat Med	2005
16007255	Liver X receptors alpha and beta regulate renin expression in vivo.	J Clin Invest	2005
15226250	Genetic markers: progress and potential for cardiovascular disease.	Circulation	2004
15451799	Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries.	Circulation	2004
15388524	Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia.	Arterioscler Thromb Vasc Biol	2004
15308553	Endothelium-targeted gene and cell-based therapies for cardiovascular disease.	Arterioscler Thromb Vasc Biol	2004
15302924	Hypoxia-regulated therapeutic gene as a preemptive treatment strategy against ischemia/reperfusion tissue injury.	Proc Natl Acad Sci U S A	2004
15353176	Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression.	Mol Cell Endocrinol	2004
15159329	Molecular and cell-based therapies for protection, rescue, and repair of ischemic myocardium: reasons for cautious optimism.	Circulation	2004
15066951	Enhanced inhibition of neointimal hyperplasia by genetically engineered endothelial progenitor cells.	Circulation	2004
14697221	Potential for germ line transmission after intramyocardial gene delivery by adeno-associated virus.	Biochem Biophys Res Commun	2004
14996990	DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line.	Physiological Genomics	2004
15054087	Gene and cell-based therapies for heart disease.	FASEB J	2004