Author details

Full Name

Michael E Weale

Affiliation

ORCID

Career Start Year

2000

Papers

108

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36989356	Dense sampling of ethnic groups within African countries reveals fine-scale genetic structure and extensive historical admixture.		2023
37620324	Analysis of subcellular RNA fractions demonstrates significant genetic regulation of gene expression in human brain post-transcriptionally.	Sci Rep	2023
33675770	Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.	Am J Cardiol	2021
30932156	Transcriptomic and genetic analyses reveal potential causal drivers for intractable partial epilepsy.	Brain	2019
30920136	The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population.	Am J Transplant	2019
31327267	Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals.	Hypertension	2019
29733446	Transethnic differences in GWAS signals: A simulation study.	Annals of Human Genetics	2018
30327483	Phenome-wide association studies across large population cohorts support drug target validation.	Nat Commun	2018
29719114	The genetic determinants of renal allograft rejection.	Am J Transplant	2018
29392897	Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.	Am J Transplant	2018
28098162	Novel genetic loci associated with hippocampal volume.	Nat Commun	2017
28469040	Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.	Sci Transl Med	2017
28844488	The Genetic Legacy of Zoroastrianism in Iran and India: Insights into Population Structure, Gene Flow, and Selection.	American Journal of Human Genetics	2017
28714974	Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.	Nat Genet	2017
28403906	An additional k-means clustering step improves the biological features of WGCNA gene co-expression networks.	BMC Syst Biol	2017
28607506	Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?	Pharmacogenomics Journal	2017
28097204	Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases.	Ann Clin Transl Neurol	2016
26797657	Systematic assessment of the influence of complement gene polymorphisms on kidney transplant outcome.	Immunobiology	2016
26912063	Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.	Mol Neurodegener	2016
27694991	Novel genetic loci underlying human intracranial volume identified through genome-wide association.	Nat Neurosci	2016
25158072	Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.	Am J Psychiatry	2015
28764847	Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12].	Neurobiol Aging	2015
25671699	Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.	PLoS Genet	2015
25607358	Common genetic variants influence human subcortical brain structures.	Nature	2015
25970246	Recursive splicing in long vertebrate genes.	Nature	2015
26394720	Network-Informed Gene Ranking Tackles Genetic Heterogeneity in Exome-Sequencing Studies of Monogenic Disease.	Hum Mutat	2015
25997848	Assessing models for genetic prediction of complex traits: a comparison of visualization and quantitative methods.	BMC Genomics	2015
26300220	Smoking Gun or Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants.	Sci Rep	2015
24873932	Genome-scale methods converge on key mitochondrial genes for the survival of human cardiomyocytes in hypoxia.	Circ Cardiovasc Genet	2014
25568836	Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme <i>CYP24A1</i> in multiple sclerosis.	Mult Scler Relat Disord	2014
24399358	The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.	Brain Imaging Behav	2014
24256812	A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis.	Hum Mol Genet	2014
25174004	Genetic variability in the regulation of gene expression in ten regions of the human brain.	Nat Neurosci	2014
24844982	A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.	PLoS One	2014
24927181	Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.	Nat Commun	2014
23666210	Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations.	Mol Biol Evol	2013
22692064	The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder.	Eur J Hum Genet	2013
24264146	Widespread sex differences in gene expression and splicing in the adult human brain.	Nat Commun	2013
23855984	Insights into TREM2 biology by network analysis of human brain gene expression data.	Neurobiol Aging	2013
23889843	Gene expression changes with age in skin, adipose tissue, blood and brain.	Genome Biol	2013
24014518	Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A.	Brain	2013
23967090	Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus.	PLoS One	2013
23783619	Scientific community: Tapping into success and collaboration.	Nature	2013
23360175	Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.	Ann Hum Genet	2013
23435227	Resolving the polymorphism-in-probe problem is critical for correct interpretation of expression QTL studies.	Nucleic Acids Res	2013
22153652	Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS.	Mol Immunol	2012
22504417	Identification of common variants associated with human hippocampal and intracranial volumes.	Nat Genet	2012
22433082	Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.	Neurobiol Dis	2012
22739346	Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs.	European Journal of Human Genetics	2012
22914738	Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.	Hum Mol Genet	2012