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Author Details
Full Name
Thomas H Hampton
Affiliation
Geisel School of Medicine, Dartmouth College
ORCID
Career Start Year
2007
Papers
68
H Index
28
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36661299
Community composition shapes microbial-specific phenotypes in a cystic fibrosis polymicrobial model system.
Elife
2023
37491532
Comparative effects of CFTR modulators on phagocytic, metabolic and inflammatory profiles of CF and nonCF macrophages.
Sci Rep
2023
37662412
Analysis of <i>Pseudomonas aeruginosa</i> transcription in an <i>ex vivo</i> cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus.
bioRxiv
2023
37577487
An In Vitro Medium for Modeling Gut Dysbiosis Associated with Cystic Fibrosis.
bioRxiv
2023
37975659
Rocket-miR, a translational launchpad for miRNA-based antimicrobial drug development.
mSystems
2023
37256658
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of <i>P. aeruginosa</i>.
Am J Physiol Lung Cell Mol Physiol
2023
37287312
PlmCas12e (CasX2) cleavage of CCR5: impact of guide RNA spacer length and PAM sequence on cleavage activity.
RNA Biol
2023
37404016
Development of the intestinal microbiome in cystic fibrosis in early life.
mSphere
2023
36711562
CAS12e (CASX2) CLEAVAGE OF CCR5: IMPACT OF GUIDE RNA LENGTH AND PAM SEQUENCE ON CLEAVAGE ACTIVITY.
bioRxiv
2023
36183834
Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.
J Biol Chem
2022
35710652
CF-Seq, an accessible web application for rapid re-analysis of cystic fibrosis pathogen RNA sequencing studies.
Sci Data
2022
36259735
ESKAPE Act Plus: Pathway Activation Analysis for Bacterial Pathogens.
mSystems
2022
33471607
CF monocyte-derived macrophages have an attenuated response to extracellular vesicles secreted by airway epithelial cells.
Am J Physiol Lung Cell Mol Physiol
2021
33795318
Healthy versus inflamed lung environments differentially affect mesenchymal stromal cells.
Eur Respir J
2021
33758032
GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses.
mSystems
2021
33727344
One versus Many: Polymicrobial Communities and the Cystic Fibrosis Airway.
mBio
2021
34579569
The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection.
mBio
2021
34544277
Model Systems to Study the Chronic, Polymicrobial Infections in Cystic Fibrosis: Current Approaches and Exploring Future Directions.
mBio
2021
34260396
Let-7b-5p in vesicles secreted by human airway cells reduces biofilm formation and increases antibiotic sensitivity of <i>P. aeruginosa</i>.
Proc Natl Acad Sci U S A
2021
34232099
Mild Cystic Fibrosis Lung Disease Is Associated with Bacterial Community Stability.
Microbiol Spectr
2021
32289118
Specificity in PDZ-peptide interaction networks: Computational analysis and review.
J Struct Biol X
2020
31685535
Availability of Zinc Impacts Interactions between Streptococcus sanguinis and Pseudomonas aeruginosa in Coculture.
J Bacteriol
2020
31980538
<i>Pseudomonas aeruginosa lasR</i> mutant fitness in microoxia is supported by an Anr-regulated oxygen-binding hemerythrin.
Proc Natl Acad Sci U S A
2020
32901521
Differential effects of the cystic fibrosis lung inflammatory environment on mesenchymal stromal cells.
Am J Physiol Lung Cell Mol Physiol
2020
32616918
Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival.
Sci Rep
2020
32668165
SARS-CoV-2 (COVID-19) and cystic fibrosis.
Am J Physiol Lung Cell Mol Physiol
2020
32521165
Selection of reference genes for quantitative PCR: identifying reference genes for airway epithelial cells exposed to <i>Pseudomonas aeruginosa</i>.
Am J Physiol Lung Cell Mol Physiol
2020
32238195
Lung function and microbiota diversity in cystic fibrosis.
Microbiome
2020
32514536
Single-cell RNA-seq Analysis Reveals That Prenatal Arsenic Exposure Results in Long-term, Adverse Effects on Immune Gene Expression in Response to Influenza A Infection.
Toxicol Sci
2020
30476744
Profiling microRNA expression in Atlantic killifish (Fundulus heteroclitus) gill and responses to arsenic and hyperosmotic stress.
Aquat Toxicol
2019
31270372
Functional and metabolic impairment in cigarette smoke-exposed macrophages is tied to oxidative stress.
Sci Rep
2019
29146575
Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa.
Am J Physiol Lung Cell Mol Physiol
2018
29979584
Arsenic Reduces Gene Expression Response to Changing Salinity in Killifish.
Environ Sci Technol
2018
28982736
An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung.
Am J Physiol Lung Cell Mol Physiol
2018
27942839
Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.
Cancer Immunol Immunother
2017
28201664
The landscape of extreme genomic variation in the highly adaptable Atlantic killifish.
Genome Biol Evol
2017
29036513
ScanGEO: parallel mining of high-throughput gene expression data.
Bioinformatics
2017
28719869
Effectiveness of table top water pitcher filters to remove arsenic from drinking water.
Environ Res
2017
27980032
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
Proc Natl Acad Sci U S A
2017
26974965
The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells.
Melanoma Res
2016
27481238
Use of a Multiplex Transcript Method for Analysis of Pseudomonas aeruginosa Gene Expression Profiles in the Cystic Fibrosis Lung.
Infect Immun
2016
27295279
A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles.
PLoS Pathog
2016
26943329
Analysis of Lung Microbiota in Bronchoalveolar Lavage, Protected Brush and Sputum Samples from Subjects with Mild-To-Moderate Cystic Fibrosis Lung Disease.
PLoS One
2016
25618892
Regulatory T cells are not a strong predictor of survival for patients with glioblastoma.
Neuro Oncol
2015
24332997
Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis.
J Cyst Fibros
2014
25408892
Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis.
Microbiome
2014
25068658
The microbiota regulates susceptibility to Fas-mediated acute hepatic injury.
Lab Invest
2014
25071935
The microbiome in pediatric cystic fibrosis patients: the role of shared environment suggests a window of intervention.
Microbiome
2014
25097758
Letter to the editor.
J Immunother Cancer
2014
25158801
Natural selection canalizes expression variation of environmentally induced plasticity-enabling genes.
Mol Biol Evol
2014
1 - 50 of 68
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row(s) 1 - 30 of 30
Collaborators
Bruce A Stanton
Dartmouth College
Co-authored papers
30
George A O'Toole
Geisel School of Medicine at Dartmouth
Co-authored papers
18
Deborah A Hogan
Geisel School of Medicine at Dartmouth
Co-authored papers
16
Mitchell L Sogin
Co-authored papers
8
Camilo E Fadul
University of Virginia Health System
Co-authored papers
8
Jiang Gui
Geisel School of Medicine at Dartmouth
Co-authored papers
5
John K Colbourne
University of Birmingham
Co-authored papers
4
Gregory J Tsongalis
Dartmouth Health and the Dartmouth Cancer Center, USA Geisel School of Medicine
Co-authored papers
3
John H Hammond
Massachusetts Institute of Technology
Co-authored papers
3
Benjamin L King
Co-authored papers
3
Juliette C Madan
Co-authored papers
3
Carolyn J Mattingly
North Carolina State University
Co-authored papers
2
Alexandra J Lee
University of Pennsylvania
Co-authored papers
2
Kathleen D Liu
University of California san francisco
Co-authored papers
2
Craig R Tomlinson
Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth
Co-authored papers
2
Casey S Greene
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers
2
Georgia Doing
Geisel School of Medicine at Dartmouth
Co-authored papers
2
Michael A Matthay
Cardiovascular Research Institute, University of California san francisco
Co-authored papers
2
Britton C Goodale
Oregon State University
Co-authored papers
2
Courtney E Price
Geisel School of Medicine at Dartmouth
Co-authored papers
1
Don Gilbert
Indiana University
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Tor D Tosteson
Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center
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Arief A Suriawinata
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