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Author Details

Tibor van Welsem
Netherlands Cancer Institute
2000
30
18
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37995691Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.Mol Cell2023
36052643The histone methyltransferase SETD2 negatively regulates cell size.J Cell Sci2022
36425063DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors <i>in vitro</i>.Front Genet2022
32299836A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in <i>S. cerevisiae</i>.J Cell Sci2020
32764145The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8<sup>+</sup> T cells.Proc Natl Acad Sci U S A2020
32188699Inhibition of transcription leads to rewiring of locus-specific chromatin proteomes.Genome Res2020
32154221Strategy for Development of Site-Specific Ubiquitin Antibodies.Front Chem2020
31304633Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.EMBO J2019
30005073Decoding the chromatin proteome of a single genomic locus by DNA sequencing.PLoS Biol2018
30203048Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.Nucleic Acids Res2018
28291796The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae.PLoS One2017
27922451Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1.Elife2016
25965993Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.Sci Rep2015
25141862Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.EMBO Rep2014
23438860A network model of the molecular organization of chromatin in Drosophila.Mol Cell2013
24360959A UV-induced genetic network links the RSC complex to nucleotide excision repair and shows dose-dependent rewiring.Cell Rep2013
23708297Recombination-induced tag exchange (RITE) cassette series to monitor protein dynamics in Saccharomyces cerevisiae.G3 (Bethesda)2013
22807688A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast.PLoS Genet2012
21291527Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.Epigenetics Chromatin2011
21998594A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.PLoS Genet2011
21760613Progressive methylation of ageing histones by Dot1 functions as a timer.EMBO Rep2011
21666805Patterns and mechanisms of ancestral histone protein inheritance in budding yeast.PLoS Biol2011
20018668Recombination-induced tag exchange to track old and new proteins.Proc Natl Acad Sci U S A2010
21084562Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei.J Cell Sci2010
18391024Synthetic lethal screens identify gene silencing processes in yeast and implicate the acetylated amino terminus of Sir3 in recognition of the nucleosome core.Mol Cell Biol2008
18511943Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states.Nat Struct Mol Biol2008
15705879Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.Cancer Res2005
12670888Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method.Cancer Res2003
12460933Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors.Cancer Res2002
11062467Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.Nat Genet2000
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Collaborators

Fred van Leeuwen
Netherlands Cancer Institute, University of Amsterdam
Co-authored papers 26
Hanneke Vlaming
Blavatnik Institute, Harvard Medical School
Co-authored papers 7
Tessy Korthout
Oncode Institute
Co-authored papers 6
Huib Ovaa
Leiden University Medical Center
Co-authored papers 4
Thom M Molenaar
Amsterdam UMC location Vrije Universiteit Amsterdam
Co-authored papers 4
Tineke L Lenstra
the Netherlands Cancer Institute, Oncode Institute
Co-authored papers 4
Deepani W Poramba-Liyanage
Utrecht University Utrecht The Netherlands.
Co-authored papers 4
Iris J E Stulemeijer
Netherlands Cancer Institute
Co-authored papers 4
Albert J R Heck
Utrecht University
Co-authored papers 3
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 3
Frank C P Holstege
Princess Maxima Center for Pediatric Oncology
Co-authored papers 3
Laura J Van't Veer
University of California San Francisco
Co-authored papers 3
Haico van Attikum
Leiden University Medical Center
Co-authored papers 3
Rohith Srivas
Amgen Inc.
Co-authored papers 2
Su Ming Sun
Leiden University Medical Center
Co-authored papers 2
Lodewyk F A Wessels
University Medical Centre Mannheim, University of Heidelberg
Co-authored papers 2
Oliver J Rando
University of Massachusetts Chan Medical School
Co-authored papers 2
Farid El Oualid
The Netherlands Cancer Institute
Co-authored papers 2
Kirsten van Harten
Netherlands Cancer Institute
Co-authored papers 2
Bas van Steensel
Oncode Institute, Netherlands Cancer Institute
Co-authored papers 1
Sovan Sarkar
CRUK MRC Oxford Institute for Radiation Oncology, University of Oxford
Co-authored papers 1
Marijke Pool
Leiden University Medical Center
Co-authored papers 1
Katherine Licon
University of California San Diego
Co-authored papers 1
Amandine Batt??
Center for Integrative Genomics, University of Lausanne
Co-authored papers 1
Su Ming Sun
Leiden University Medical Center
Co-authored papers 1
Erik Malta
Leiden University Medical Center
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Peter J McHugh
MRC Weatherall Institute of Molecular Medicine, University of Oxford
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George Q Daley
Boston Children's Hospital, Harvard Medical School
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Release 1.2