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Author Details

Anita M Preininger
IBM Corporation
2002
36
19
PMIDPaper TitleJournal TitlePublished Year
33439724Artificial Intelligence Clinical Evidence Engine for Automatic Identification, Prioritization, and Extraction of Relevant Clinical Oncology Research.JCO Clin Cancer Inform2021
33769304Accuracy of an Artificial Intelligence System for Cancer Clinical Trial Eligibility Screening: Retrospective Pilot Study.JMIR Med Inform2021
33517402Leveraging conversational technology to answer common COVID-19 questions.J Am Med Inform Assoc2021
33517389Comparison of an oncology clinical decision-support system's recommendations with actual treatment decisions.J Am Med Inform Assoc2021
34956712The Potential and the Imperative: the Gap in AI-Related Clinical Competencies and the Need to Close It.Med Sci Educ2021
34027610Health Care Equity in the Use of Advanced Analytics and Artificial Intelligence Technologies in Primary Care.J Gen Intern Med2021
34332466Differences in information accessed in a pharmacologic knowledge base using a conversational agent vs traditional search methods.Int J Med Inform2021
32734161Evaluation of an artificial intelligence clinical trial matching system in Australian lung cancer patients.JAMIA Open2020
31977254Artificial Intelligence Tool for Optimizing Eligibility Screening for Clinical Trials in a Large Community Cancer Center.JCO Clin Cancer Inform2020
32970484Effect of an Artificial Intelligence Clinical Decision Support System on Treatment Decisions for Complex Breast Cancer.JCO Clin Cancer Inform2020
32734163Artificial intelligence-based conversational agent to support medication prescribing.JAMIA Open2020
31419814AI in Health: State of the Art, Challenges, and Future Directions.Yearb Med Inform2019
28515322Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.J Biol Chem2017
24292645Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.Nat Struct Mol Biol2014
24596087A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1.J Biol Chem2014
23159802Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans.J Struct Biol2013
23602809Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective.J Mol Biol2013
23466875Linking receptor activation to changes in Sw I and II of Gα proteins.J Struct Biol2013
22052489Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective.Methods Mol Biol2012
22329346Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution.Biochemistry2012
21375271Coupling efficiency of rhodopsin and transducin in bicelles.Biochemistry2011
21606326Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit.Proc Natl Acad Sci U S A2011
19222191Helix dipole movement and conformational variability contribute to allosteric GDP release in Galphai subunits.Biochemistry2009
19760664Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.Protein Sci2009
19483102Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates.Mol Pharmacol2009
18771287Receptor-mediated changes at the myristoylated amino terminus of Galpha(il) proteins.Biochemistry2008
17194150Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm.Anal Chem2007
17954242Biochemical analysis of phospholipase D.Methods Enzymol2007
17463080Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins.Proc Natl Acad Sci U S A2007
16638972Direct modulation of phospholipase D activity by Gbetagamma.Mol Pharmacol2006
16892066Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.Nat Struct Mol Biol2006
15778713G protein betagamma directly regulates SNARE protein fusion machinery for secretory granule exocytosis.Nat Neurosci2005
14762218G protein signaling: insights from new structures.Sci STKE2004
12834345The myristoylated amino terminus of Galpha(i)(1) plays a critical role in the structure and function of Galpha(i)(1) subunits in solution.Biochemistry2003
14671004Insights into G protein structure, function, and regulation.Endocr Rev2003
12146960Conformational changes in the amino-terminal helix of the G protein alpha(i1) following dissociation from Gbetagamma subunit and activation.Biochemistry2002
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Collaborators

Co-authored papers 21
Vanderbilt University Medical Center
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& Center for AI
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Harvard Medical School
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University of Utah
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Vanderbilt University
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Vagelos College of Physicians and Surgeons, Columbia University
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University of Pittsburgh
Co-authored papers 1
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Mayo Clinic
Co-authored papers 1
Vanderbilt University School of Medicine
Co-authored papers 1
IBM Corporation
Co-authored papers 1
Vanderbilt University School of Medicine
Co-authored papers 1
Vanderbilt University
Co-authored papers 1
The Hospital for Sick Children
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Center for Advanced Mobile Healthcare Learning, Vanderbilt University Medical Center
Co-authored papers 1
Department of Pharmacy, 5Peter MacCallum Cancer Centre
Co-authored papers 1
Clinical Evidence Development, Center for AI
Co-authored papers 1
Peter MacCallum Cancer Centre
Co-authored papers 1
Brigham and Women's Hospital
Co-authored papers 1