Author details

Full Name

Nir Barzilai

Affiliation

ORCID

Career Start Year

1981

Papers

300

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37464278	Association of a Blood-Based Aging Biomarker Index With Death and Chronic Disease: Cardiovascular Health Study.	J Gerontol A Biol Sci Med Sci	2024
36722290	A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.	EMBO J	2023
35948858	High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity.	GeroScience	2023
35997888	A metabolomic signature of the APOE2 allele.	Geroscience	2023
37605876	Targeted sequencing of the 9p21.3 region reveals association with reduced disease risks in Ashkenazi Jewish centenarians.		2023
37598227	Challenges in developing Geroscience trials.	Nat Commun	2023
37657418	Biomarkers of aging for the identification and evaluation of longevity interventions.	Cell	2023
38057571	Organ aging signatures in the plasma proteome track health and disease.	Nature	2023
37339345	Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2.	Diabetes Care	2023
37202472	SuperAger Initiative: unlocking the genetic potential of exceptional longevity.	Nat Aging	2023
37137499	Discovering Biological Mechanisms of Exceptional Human Health Span and Life Span.		2023
37389519	Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement.	J Am Coll Cardiol	2023
37246648	Frailty Resilience Score: A Novel Measure of Frailty Resilience Associated With Protection From Frailty and Survival.		2023
37365260	Defining a longevity biotechnology company.		2023
36463714	Age-related changes in gait domains: Results from the LonGenity study.		2023
37292828	The regulation of Insulin/IGF-1 signaling by miR-142-3p associated with human longevity.	bioRxiv	2023
36453627	Cognition, function, and prevalent dementia in centenarians and near-centenarians: An individual participant data (IPD) meta-analysis of 18 studies.	Alzheimer's and Dementia	2023
37291596	Aging and chronic inflammation: highlights from a multidisciplinary workshop.	Immun Ageing	2023
36843279	Biological Age Acceleration and Motoric Cognitive Risk Syndrome.		2023
35343051	Geroscience-guided repurposing of FDA-approved drugs to target aging: A proposed process and prioritization.	Aging Cell	2022
35770332	Integrity of hypothalamic-pituitary-testicular axis in exceptional longevity.	Aging Cell	2022
36038634	Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.	Nat Genet	2022
35932241	New horizons in life extension, healthspan extension and exceptional longevity.	Age and Ageing	2022
36324399	Inflammatory biomarkers and motoric cognitive risk syndrome: Multicohort survey.	Cerebral Circulation - Cognition and Behavior	2022
36384162	Quantum Healthy Longevity for healthy people, planet, and growth.	Lancet Healthy Longev	2022
36613555	A Genome-Wide Association Study of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants.	Int J Mol Sci	2022
36455558	Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14 century.	Cell	2022
34791239	Relative Trajectories of Gait and Cognitive Decline in Aging.		2022
34498278	Extending human healthspan and longevity: a symposium report.	Ann N Y Acad Sci	2022
34363732	The antagonistic pleiotropy of insulin-like growth factor 1.	Aging Cell	2021
37117627	Rare genetic coding variants associated with human longevity and protection against age-related diseases.	Nat Aging	2021
34285117	Modulation of Glucose Production by Central Insulin Requires IGF-1 Receptors in AgRP Neurons.		2021
33893282	Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes.	Nat Commun	2021
33948810	Effect of longevity genetic variants on the molecular aging rate.	Geroscience	2021
34108472	Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.	Nat Commun	2021
34197020	Genetic signature of human longevity in PKC and NF-ÎºB signaling.	Aging Cell	2021
34143375	Correction to: Effect of longevity genetic variants on the molecular aging rate.	Geroscience	2021
34140970	A Compendium of Age-Related PheWAS and GWAS Traits for Human Genetic Association Studies, Their Networks and Genetic Correlations.	Frontiers in Genetics	2021
34252094	Trajectories of frailty in aging: Prospective cohort study.	PLoS ONE	2021
32902818	A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.	GeroScience	2021
33164815	Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-Îµ4 carriers.	Neurobiol Aging	2021
34463901	Einstein-Nathan Shock Center: translating the hallmarks of aging to extend human health span.	Geroscience	2021
32719537	Genetics of extreme human longevity to guide drug discovery for healthy ageing.	Nat Metab	2020
37113577	Development of an IGF1R longevity variant mouse line using CRISPR/Cas9 genome editing.	Trends Biomed Res	2020
32203922	Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A.	Redox Biology	2020
32333835	Benefits of Metformin in Attenuating the Hallmarks of Aging.		2020
32492897	Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults.	Cells	2020
33378272	ARDD 2020: from aging mechanisms to interventions.	Aging (Albany NY)	2020
32765937	Geroscience in the Age of COVID-19.	Aging Dis	2020
32762010	Plasma proteomic profile of frailty.	Aging Cell	2020