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Author Details

Michelle J Henderson
Children's Cancer Institute, Lowy Cancer Research Centre
2002
51
25
PMIDPaper TitleJournal TitlePublished Year
34471258Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.Br J Cancer2022
35677155The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.Front Oncol2022
35650277Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions.Br J Cancer2022
35454786Suppression of the ABCA1 Cholesterol Transporter Impairs the Growth and Migration of Epithelial Ovarian Cancer.Cancers (Basel)2022
35127484Systematic <i>In Vitro</i> Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia.Front Oncol2022
33994371Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.Clin Cancer Res2021
33565233Are outcomes for childhood leukaemia in Australia influenced by geographical remoteness and Indigenous race?Pediatr Blood Cancer2021
33638292Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomab.Pediatr Blood Cancer2021
33918978A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma.Cancers (Basel)2021
33837299Exploiting the reactive oxygen species imbalance in high-risk paediatric acute lymphoblastic leukaemia through auranofin.Br J Cancer2021
33497018The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma.Mol Oncol2021
31325323Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia.Int J Cancer2020
31896781OT-82, a novel anticancer drug candidate that targets the strong dependence of hematological malignancies on NAD biosynthesis.Leukemia2020
31862449CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth.Biochem Pharmacol2020
31848452Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia.Leukemia2020
32651259Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.Cancer Res2020
32554541Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).Clin Cancer Res2020
32473302Prognostic gene expression signature for high-grade serous ovarian cancer.Ann Oncol2020
32277480ABCC4/MRP4 contributes to the aggressiveness of Myc-associated epithelial ovarian cancer.Int J Cancer2020
30670779A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.Oncogene2019
31690716The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.Nat Commun2019
31360864Clinical Importance of Myc Family Oncogene Aberrations in Epithelial Ovarian Cancer.JNCI Cancer Spectr2018
27923830A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers.Cancer Res2017
28735070Suppression of the ATP-binding cassette transporter ABCC4 impairs neuroblastoma tumour growth and sensitises to irinotecan in vivo.Eur J Cancer2017
26840454Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer.Oncotarget2016
27317766CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.Oncotarget2016
27180306ABC transporters as mediators of drug resistance and contributors to cancer cell biology.Drug Resist Updat2016
26767510Enumeration of extracellular vesicles by a new improved flow cytometric method is comparable to fluorescence mode nanoparticle tracking analysis.Nanomedicine2016
25573381Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.Clin Cancer Res2015
24957074ABCA transporter gene expression and poor outcome in epithelial ovarian cancer.J Natl Cancer Inst2014
24973542High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4).Biochem Pharmacol2014
24810093Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer.Sci Rep2014
23917080ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas.Gynecol Oncol2013
23267433ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma.Front Oncol2012
21799180ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.J Natl Cancer Inst2011
20075923ABC transporters in cancer: more than just drug efflux pumps.Nat Rev Cancer2010
20544796alpha4 phosphoprotein interacts with EDD E3 ubiquitin ligase and poly(A)-binding protein.J Cell Biochem2010
20233711Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells.J Biol Chem2010
20167605Modulation of myocardin function by the ubiquitin E3 ligase UBR5.J Biol Chem2010
18418081Mechanism of relapse in pediatric acute lymphoblastic leukemia.Cell Cycle2008
18218047A xenograft model of infant leukaemia reveals a complex MLL translocation.Br J Haematol2008
18349819The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro.Br J Cancer2008
17371950Relapse in children with acute lymphoblastic leukemia involving selection of a preexisting drug-resistant subclone.Blood2007
18073532The E3 ubiquitin ligase EDD regulates S-phase and G(2)/M DNA damage checkpoints.Cell Cycle2007
18085475Role of the MRP1/ABCC1 multidrug transporter protein in cancer.IUBMB Life2007
18076571Putative tumor suppressor EDD interacts with and up-regulates APC.Genes Cells2007
17074762EDD mediates DNA damage-induced activation of CHK2.J Biol Chem2006
15282321Edd, the murine hyperplastic disc gene, is essential for yolk sac vascularization and chorioallantoic fusion.Mol Cell Biol2004
12594221Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs.J Biol Chem2003
12902990EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer.Oncogene2003
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Collaborators

Michelle Haber
School of Clinical Medicine
Co-authored papers 34
Jamie I Fletcher
Co-authored papers 10
Anna DeFazio
Westmead Hospital
Co-authored papers 10
Chelsea Mayoh
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 9
Glenn M Marshall
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 8
Richard B Lock
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers 7
David D L Bowtell
Peter MacCallum Cancer Centre
Co-authored papers 7
Georgia Chenevix-Trench
QIMR Berghofer Medical Research Institute
Co-authored papers 6
Peter A Fasching
Otto-Friedrich-University Bamberg
Co-authored papers 5
Andrew Berchuck
Duke School of Medicine
Co-authored papers 5
Joshy George
Peter MacCallum Cancer Centre
Co-authored papers 5
Sharon E Johnatty
QIMR Berghofer Medical Research Institute
Co-authored papers 5
Bo Gao
Crown Princess Mary Cancer Centre, Westmead Hospital
Co-authored papers 5
Jenny Lester
David Geffen School of Medicine, University of California at Los Angeles
Co-authored papers 5
Ellen L Goode
Mayo Clinic College of Medicine
Co-authored papers 5
Joellen M Schildkraut
Rollins School of Public Health, Emory University
Co-authored papers 4
Pamela J Thompson
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 4
Sandra Orsulic
David Geffen School of Medicine, University of California at Los Angeles
Co-authored papers 4
Paul Harnett
Westmead Clinical School, University of Sydney
Co-authored papers 4
Catherine J Kennedy
The Westmead Institute for Medical Research, University of Sydney
Co-authored papers 4
Beth Y Karlan
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
Xiaoqing Chen
QIMR Berghofer Medical Research Institute
Co-authored papers 4
Marc T Goodman
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 4
Jonathan Beesley
QIMR Berghofer Medical Research Institute
Co-authored papers 4
Andreas du Bois
Co-authored papers 3
Brooke L Fridley
H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 3
Tanja Pejovic
Oregon Health & Science University
Co-authored papers 3
Mark J Cowley
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Release 1.2