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Author Details

Wei Wu
University of California
1996
41
28
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37543137Buprenorphine and methadone differentially alter early brain development in human cortical organoids.Neuropharmacology2023
36202289Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids.Neurobiol Dis2022
35501322Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content.Nat Commun2022
33888873Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy.Mol Psychiatry2021
33328864Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids.Front Neurosci2020
33137567Methadone interrupts neural growth and function in human cortical organoids.Stem Cell Res2020
31474560Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development.Cell Stem Cell2019
29355592Down-regulation of Inwardly Rectifying K<sup>+</sup> Currents in Astrocytes Derived from Patients with Monge's Disease.Neuroscience2018
28765282The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut-liver-kidney axis.J Biol Chem2017
28694431Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes.Sci Rep2017
27274832Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling.Clin Kidney J2016
27440044An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.J Biol Chem2016
27488918Molecular Properties of Drugs Interacting with SLC22 Transporters OAT1, OAT3, OCT1, and OCT2: A Machine-Learning Approach.J Pharmacol Exp Ther2016
25540139The organic anion transporter (OAT) family: a systems biology perspective.Physiol Rev2015
26490509Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.Clin J Am Soc Nephrol2015
26358290Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors.Drug Metab Dispos2015
26536134Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs.PLoS One2015
23196129Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue.Neurosci Lett2013
23920220Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways.Drug Metab Dispos2013
23949796Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease.J Am Soc Nephrol2013
22542180Complementary chimeric isoforms reveal Dscam1 binding specificity in vivo.Neuron2012
20921221Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling.J Biol Chem2011
21652719Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury.J Biol Chem2011
21757732Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis.J Biol Chem2011
21325265Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis.Mol Pharmacol2011
21493727Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney.Mol Pharmacol2011
19439520Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function.Am J Physiol Renal Physiol2009
19934016Neuropeptide Y functions as a facilitator of GDNF-induced budding of the Wolffian duct.Development2009
19417012Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members.Physiol Genomics2009
18216144Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics.Am J Physiol Renal Physiol2008
19066399Analysis of metagene portraits reveals distinct transitions during kidney organogenesis.Sci Signal2008
19279725Organogenesis forum lecture: In vitro kidney development, tissue engineering and systems biology.Organogenesis2008
18805093A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms.Cell2008
18508962Organic anion transporter 3 contributes to the regulation of blood pressure.J Am Soc Nephrol2008
17889655A vast repertoire of Dscam binding specificities arises from modular interactions of variable Ig domains.Cell2007
17554308Dscam2 mediates axonal tiling in the Drosophila visual system.Nature2007
16648942Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).J Hum Genet2006
17094945Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions.Biochem Biophys Res Commun2006
16678101Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.Cell2006
11087842Regulation of somatic growth by the p160 coactivator p/CIP.Proc Natl Acad Sci U S A2000
8934515Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism.Nature1996
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Collaborators

university of california san diego
Co-authored papers 26
university of california san diego
Co-authored papers 8
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 6
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 5
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 4
University of Washington
Co-authored papers 3
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Co-authored papers 3
University of California San Diego
Co-authored papers 3
Co-authored papers 3
University of California San Diego
Co-authored papers 3
University of California
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of California
Co-authored papers 1
University of California, San Diego School of Medicine
Co-authored papers 1
Zuckerman Mind Brain Behaviour Institute
Co-authored papers 1
Center for Epigenomics, University of California
Co-authored papers 1
Center for Epigenomics, University of California San Diego School of Medicine
Co-authored papers 1
Medical Clinic and Policlinic IV, University of Munich
Co-authored papers 1
Herbert Wertheim School of Public Health, University of California
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California
Co-authored papers 1
Folkhalsan Institute of Genetics, Folkhalsan Research Center
Co-authored papers 1
Institute for Genomic Health, Icahn School of Medicine at Mount Sinai
Co-authored papers 1
University of California at San Diego
Co-authored papers 1
University of Michigan-Ann Arbor
Co-authored papers 1
Clinical Metabolomics
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
National Institutes of Health, National Institute of Diabetes
Co-authored papers 1
University of California, San Diego School of Medicine
Co-authored papers 1