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Author Details

Udupi A Ramagopal
Poornaprajna Institute of Scientific Research (PPISR)
1998
55
27
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35504420High-resolution crystal structure of LpqH, an immunomodulatory surface lipoprotein of Mycobacterium tuberculosis reveals a distinct fold and a conserved cleft on its surface.Int J Biol Macromol2022
34191384Cryptic association of B7-2 molecules and its implication for clustering.Protein Sci2021
34709351HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.J Exp Med2021
34146695A structural perspective on the design of decoy immune modulators.Pharmacol Res2021
31230945Structural Basis of CD160:HVEM Recognition.Structure2019
31844079The CC' loop of IgV domains of the immune checkpoint receptors, plays a key role in receptor:ligand affinity modulation.Sci Rep2019
29261291Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module.Biochemistry2018
29694705Crystal structures of APRT from Francisella tularensis - an N-H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases.FEBS J2018
29767960Comparison of Alicyclobacillus acidocaldarius o-Succinylbenzoate Synthase to Its Promiscuous N-Succinylamino Acid Racemase/ o-Succinylbenzoate Synthase Relatives.Biochemistry2018
27978489Structural, mutational and biophysical studies reveal a canonical mode of molecular recognition between immune receptor TIGIT and nectin-2.Mol Immunol2017
28484017Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab.Proc Natl Acad Sci U S A2017
28368276The hidden treasure in your data: phasing with unexpected weak anomalous scatterers from routine data sets.Acta Crystallogr F Struct Biol Commun2017
28233730Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy.EBioMedicine2017
28643473Can the propensity of protein crystallization be increased by using systematic screening with metals?Protein Sci2017
27806260Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.Structure2016
27583447A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.PLoS Pathog2016
24916461Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors.Nat Commun2014
25437562Structure and cancer immunotherapy of the B7 family member B7x.Cell Rep2014
23583034Functional classification of immune regulatory proteins.Structure2013
24252706Structure of the S100A4/myosin-IIA complex.BMC Struct Biol2013
23848398Structural basis for the divergence of substrate specificity and biological function within HAD phosphatases in lipopolysaccharide and sialic acid biosynthesis.Biochemistry2013
23583036Structure and T cell inhibition properties of B7 family member, B7-H3.Structure2013
22927415Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.Proc Natl Acad Sci U S A2012
230357851-methylthio-D-xylulose 5-phosphate methylsulfurylase: a novel route to 1-deoxy-D-xylulose 5-phosphate in Rhodospirillum rubrum.Biochemistry2012
21300286Decoy strategies: the structure of TL1A:DcR3 complex.Structure2011
21825122Structural and functional characterization of a single-chain peptide-MHC molecule that modulates both naive and activated CD8+ T cells.Proc Natl Acad Sci U S A2011
20093428Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect.Int Immunol2010
20421509Phenothiazines inhibit S100A4 function by inducing protein oligomerization.Proc Natl Acad Sci U S A2010
19251641Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.Proc Natl Acad Sci U S A2009
19426233Sequence, structure, function, immunity: structural genomics of costimulation.Immunol Rev2009
193901481.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.Acta Crystallogr D Biol Crystallogr2009
18182486Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.Proc Natl Acad Sci U S A2008
18760284Crystal structure of Escherichia coli Rnk, a new RNA polymerase-interacting protein.J Mol Biol2008
18641123Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2.Proc Natl Acad Sci U S A2008
18410126Structure of Ca2+-bound S100A4 and its interaction with peptides derived from nonmuscle myosin-IIA.Biochemistry2008
18154341L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.J Am Chem Soc2008
17363302T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface.Immunity2007
18040044Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.Proc Natl Acad Sci U S A2007
18058037Structural genomics of protein phosphatases.J Struct Funct Genomics2007
17678528Observation of glycine zipper and unanticipated occurrence of ambidextrous helices in the crystal structure of a chiral undecapeptide.BMC Struct Biol2007
16403515A structural basis for the role of nucleotide specifying residues in regulating the oligomerization of the Rv1625c adenylyl cyclase from M. tuberculosis.J Mol Biol2006
17045824NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family.Immunity2006
16772301Structure-function analysis and insights into the reduced toxicity of Abrus precatorius agglutinin I in relation to abrin.J Biol Chem2006
16411186Stabilization of unusual structures in peptides using alpha,beta-dehydrophenylalanine: crystal and solution structures of Boc-Pro-DeltaPhe-Val-DeltaPhe-Ala-OMe and Boc-Pro-DeltaPhe-Gly-DeltaPhe-Ala-OMe.Biopolymers2006
16131763Radiation-induced site-specific damage of mercury derivatives: phasing and implications.Acta Crystallogr D Biol Crystallogr2005
16511207The ybeY protein from Escherichia coli is a metalloprotein.Acta Crystallogr Sect F Struct Biol Cryst Commun2005
15159568Structural effects of radiation damage and its potential for phasing.Acta Crystallogr D Biol Crystallogr2004
15274920Structure of the actin crosslinking core of fimbrin.Structure2004
15016355De novo design and characterization of a helical hairpin eicosapeptide; emergence of an anion receptor in the linker region.Structure2004
12777765Phasing on anomalous signal of sulfurs: what is the limit?Acta Crystallogr D Biol Crystallogr2003
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Collaborators

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Co-authored papers 36
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Co-authored papers 10
The State University of New Jersey
Co-authored papers 6
Albert Einstein College of Medicine
Co-authored papers 6
Albert Einstein College of Medicine
Co-authored papers 6
Eli Lilly and Co.
Co-authored papers 5
Universidad Cardenal Herrera-CEU, CEU Universities
Co-authored papers 5
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 4
Albert Einstein College of Medicine
Co-authored papers 3
New York University Grossman School of Medicine
Co-authored papers 3
Albert Einstein College of Medicine
Co-authored papers 3
Medical College of Wisconsin
Co-authored papers 2
Case Western Reserve University
Co-authored papers 2
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Brookhaven National Laboratory
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Faculdade de Farmacia, Universidade Federal do Rio de Janeiro
Co-authored papers 1
University of Illinois at Urbana-Champaign
Co-authored papers 1
Texas A&M University, College Station
Co-authored papers 1
University of Virginia
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1
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The Rockefeller University
Co-authored papers 1
National Forensic Sciences University
Co-authored papers 1
Boston University
Co-authored papers 1
Manipal University Jaipur
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Gladstone Institutes
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University of Mysore
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