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Author Details

M Ryan Corces
Gladstone Institute of Neurological Disease
2010
39
29
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37587197Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature.Nat Commun2023
35093191Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility.Neuron2022
35478247Chromatin accessibility profiling by ATAC-seq.Nat Protoc2022
35532363The Cell Type-Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia.Blood Cancer Discov2022
36466610Deep learning approaches for noncoding variant prioritization in neurodegenerative diseases.Front Aging Neurosci2022
36333818Single-cell spatial proteomic imaging for human neuropathology.Acta Neuropathol Commun2022
34341533LKB1 inactivation modulates chromatin accessibility to drive metastatic progression.Nat Cell Biol2021
33790476Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis.Nat Genet2021
33633365ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis.Nat Genet2021
34859208PEPATAC: an optimized pipeline for ATAC-seq data analysis with serial alignments.NAR Genom Bioinform2021
34819668ecDNA hubs drive cooperative intermolecular oncogene expression.Nature2021
34516796Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury.Science2021
34568834Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia.Blood Cancer Discov2021
34418357GATM and GAMT synthesize creatine locally throughout the mammalian body and within oligodendrocytes of the brain.Brain Res2021
32150611Single-cell mutational profiling enhances the clinical evaluation of AML MRD.Blood Adv2020
33106633Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer's and Parkinson's diseases.Nat Genet2020
30958261Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA.Elife2019
31375813Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion.Nat Biotechnol2019
31133759HiChIRP reveals RNA-associated chromosome conformation.Nat Methods2019
29706549Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.Cell2018
30361341The chromatin accessibility landscape of primary human cancers.Science2018
29686426Transcript-indexed ATAC-seq for precision immune profiling.Nat Med2018
28846090An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues.Nat Methods2017
28089908Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.Cell Stem Cell2017
28954238Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to Neurons.Cell Rep2017
29164062Preleukemic Hematopoietic Stem Cells in Human Acute Myeloid Leukemia.Front Oncol2017
28945252Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.Nat Genet2017
28729405Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist.Cancer Discov2017
26855137The three-dimensional cancer genome.Curr Opin Genet Dev2016
27526324Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution.Nat Genet2016
27213817A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.Nat Med2016
25398938Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.Blood2015
26607380Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.Cell Stem Cell2015
25599133Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia.Nat Med2015
24550281Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission.Proc Natl Acad Sci U S A2014
25005245Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis.Leukemia2014
22932223Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.Sci Transl Med2012
21423168A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression.Nature2011
20502519Insulin signaling and dietary restriction differentially influence the decline of learning and memory with age.PLoS Biol2010
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Collaborators

Center for Personal Dynamic Regulomes, Stanford University
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Stanford University School of Medicine
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Broad Institute of MIT and Harvard
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Stanford University.
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Harvard University, Broad Institute of MIT and Harvard
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Boston Children's Hospital
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University of California San Diego
Co-authored papers 3
Rowan University School of Osteopathic Medicine
Co-authored papers 3
AbbVie Inc.
Co-authored papers 3
Center for Genomic Integrity, Institute for Basic Science
Co-authored papers 3
Stanford Center for Biomedical Informatics Research, Stanford University
Co-authored papers 2
Ulster University
Co-authored papers 2
Stanford University
Co-authored papers 2
Cancer Institute, Stanford University School of Medicine
Co-authored papers 2
CNRS, Institut Curie, PSL Research University, Universite Paris Cite
Co-authored papers 1
MS Research Unit
Co-authored papers 1
Universidade da Coruna
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University of California San Diego
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Bluestar Genomics Inc.
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Center for Personal Dynamic Regulomes, Stanford University School of Medicine
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National Cancer Institute
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