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Author Details

Kevin L Grove
Novo Nordisk Research Center Seattle
1989
150
54
PMIDPaper TitleJournal TitlePublished Year
35917179Sustained inhibition of NPY/AgRP neuronal activity by FGF1.JCI Insight2022
33245952Evaluation of VGF peptides as potential anti-obesity candidates in pre-clinical animal models.Peptides2021
32350364Whole transcriptome analysis and validation of metabolic pathways in subcutaneous adipose tissues during FGF21-induced weight loss in non-human primates.Sci Rep2020
32895383Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission.Nat Commun2020
30674622Determining the Effects of Combined Liraglutide and Phentermine on Metabolic Parameters, Blood Pressure, and Heart Rate in Lean and Obese Male Mice.Diabetes2019
30006583Maternal high-fat diet reversal improves placental hemodynamics in a nonhuman primate model of diet-induced obesity.Int J Obes (Lond)2019
31230943Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons.Mol Metab2019
30809795The central fibroblast growth factor receptor/beta klotho system: Comprehensive mapping in Mus musculus and comparisons to nonhuman primate and human samples using an automated in situ hybridization platform.J Comp Neurol2019
30773465A Long-Acting PYY<sub>3-36</sub> Analog Mediates Robust Anorectic Efficacy with Minimal Emesis in Nonhuman Primates.Cell Metab2019
30879984Case Reports of Pre-clinical Replication Studies in Metabolism and Diabetes.Cell Metab2019
29621980Modulations in the offspring gut microbiome are refractory to postnatal synbiotic supplementation among juvenile primates.BMC Microbiol2018
29892039FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys.Int J Obes (Lond)2018
30026488Hypothalamic oxidative stress and inflammation, and peripheral glucose homeostasis in Sprague-Dawley rat offspring exposed to maternal and postnatal chocolate and soft drink.Nutr Diabetes2018
28443480Adverse Placental Perfusion and Pregnancy Outcomes in a New Nonhuman Primate Model of Gestational Protein Restriction.Reprod Sci2018
28561903Arcuate nucleus neuropeptide coexpression and connections to gonadotrophin-releasing hormone neurones in the female rhesus macaque.J Neuroendocrinol2017
28404581Maternal and postnatal high-fat diet consumption programs energy balance and hypothalamic melanocortin signaling in nonhuman primate offspring.Am J Physiol Regul Integr Comp Physiol2017
28092346Differential hypothalamic leptin sensitivity in obese rat offspring exposed to maternal and postnatal intake of chocolate and soft drink.Nutr Diabetes2017
28144621GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance.eNeuro2017
26977392Postnatal undernutrition delays a key step in the maturation of hypothalamic feeding circuits.Mol Metab2016
26554594The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.Am J Physiol Endocrinol Metab2016
27734025Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques.JCI Insight2016
27811965Genomic Variants Associated with Resistance to High Fat Diet Induced Obesity in a Primate Model.Sci Rep2016
27688995α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors.Mol Metab2016
27207517Temporal Changes in Skeletal Muscle Capillary Responses and Endothelial-Derived Vasodilators in Obesity-Related Insulin Resistance.Diabetes2016
27357159Vasoconstrictor eicosanoids and impaired microvascular function in inactive and insulin-resistant primates.Int J Obes (Lond)2016
25380238Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain.Endocrinology2015
26459134Melanocortin agonists stimulate lipolysis in human adipose tissue explants but not in adipocytes.BMC Res Notes2015
26530932Maternal high-fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring.Obesity (Silver Spring)2015
26076035Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion.Nat Med2015
26042199Ghrelin.Mol Metab2015
26041922Developmental changes in synaptic distribution in arcuate nucleus neurons.J Neurosci2015
26145226Influence of high fat diet and resveratrol supplementation on placental fatty acid uptake in the Japanese macaque.Placenta2015
25933822Impact of maternal obesity on fetal programming of cardiovascular disease.Physiology (Bethesda)2015
25763829Gadolinium Chelate Contrast Material in Pregnancy: Fetal Biodistribution in the Nonhuman Primate.Radiology2015
25788674Peroxisome proliferator-activated receptor γ controls ingestive behavior, agouti-related protein, and neuropeptide Y mRNA in the arcuate hypothalamus.J Neurosci2015
23736354Increased fibroblast growth factor 21 expression in high-fat diet-sensitive non-human primates (Macaca mulatta).Int J Obes (Lond)2014
25480301Leptin mediates the increase in blood pressure associated with obesity.Cell2014
25202980The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.J Clin Invest2014
25307860Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism.Cell Metab2014
25011649Endogenous kisspeptin tone is a critical excitatory component of spontaneous GnRH activity and the GnRH response to NPY and CART.Neuroendocrinology2014
25057200Developmental switch of leptin signaling in arcuate nucleus neurons.J Neurosci2014
24846660High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model.Nat Commun2014
24844258Consumption of a Western-style diet during pregnancy impairs offspring islet vascularization in a Japanese macaque model.Am J Physiol Endocrinol Metab2014
24569549The nonhuman primate as a model for type 2 diabetes.Curr Opin Endocrinol Diabetes Obes2014
24563374Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates.FASEB J2014
24705404Early life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates.Diabetes2014
24163066Proinflammatory endothelial activation detected by molecular imaging in obese nonhuman primates coincides with onset of insulin resistance and progressively increases with duration of insulin resistance.Circulation2014
22450853Maternal high-fat diet impacts endothelial function in nonhuman primate offspring.Int J Obes (Lond)2013
24049738Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques.Mol Metab2013
24048859Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice.J Neurosci2013
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Collaborators

M S Smith
Oregon National Primate Research Center, Oregon Health & Science University
Co-authored papers 51
Xiao Qiu Xiao
Oregon National Primate Research Center, Oregon Health & Science University
Co-authored papers 7
Judy L Cameron
University of Pittsburgh
Co-authored papers 4
Daniel L Marks
Pape Family Pediatric Research Institute, Oregon Health & Science University
Co-authored papers 4
Jian-Ying Zhou
Co-authored papers 1
Vicente Herranz-P??rez
Cavanilles Institute, University of Valencia
Co-authored papers 1
Christopher B Newgard
Duke Molecular Physiology Institute
Co-authored papers 1
Eliot R Spindel
Co-authored papers 1
Abraham A Palmer
McMaster University & St. Joseph's Healthcare Hamilton
Co-authored papers 1
Richard D Smith
Pacific Northwest National Laboratory
Co-authored papers 1
See Yan Lau
e Department of Pharmacy
Co-authored papers 1
Zaman Mirzadeh
Barrow Neurological Institute, St. Joseph's Hospital and Medical Center
Co-authored papers 1
Ismaa Sadaf Farooqi
Co-authored papers 1
Peter R Levasseur
Pape Family Pediatric Research Institute, Oregon Health & Science University
Co-authored papers 1
Jos?? Manuel Garc??a-Verdugo
Cavanilles Institute, University of Valencia
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Michael W W Adams
University of Georgia
Co-authored papers 1
Sara A Murray
Novo Nordisk Research Center Seattle
Co-authored papers 1
Kirk C Hansen
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Wei-Jun Qian
Co-authored papers 1
Stephen O'Rahilly
Co-authored papers 1
Christopher J Madden
University of Texas Southwestern Medical Center
Co-authored papers 1
Travis Nemkov
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Serge Luquet
Universite de Paris, CNRS
Co-authored papers 1
Guanghou Shui
Co-authored papers 1
Matthew J Watt
Co-authored papers 1
Andrea L Hevener
Co-authored papers 1
Tune H Pers
Co-authored papers 1
Thomas Sparsø
Co-authored papers 1
Christopher J Lynch
Co-authored papers 1
Release 1.2