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Author Details

Didier Surdez
Balgrist University Hospital, University of Zurich (UZH)
2005
59
26
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36502618Staging of newly diagnosed Ewing sarcoma: Results of bone marrow aspiration and biopsy versus (18)FDG-PET/CT imaging for bone marrow involvement.Eur J Cancer2023
37863903Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups.Nat Commun2023
37942508Simple droplet microfluidics platform for drug screening on cancer spheroids.Lab Chip2023
37723198A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors.Commun Biol2023
37142597Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma.Nat Commun2023
37236926SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.Nat Commun2023
37202469Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts.NPJ Precis Oncol2023
36753540Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.Sci Adv2023
36787739Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding.Am J Hum Genet2023
36462556High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-X<sub>L</sub> inhibition against Ewing sarcoma.Cancer Lett2023
36602782Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models.Clin Cancer Res2023
33241676The epigenetic regulator RINF (CXXC5) maintains <i>SMAD7</i> expression in human immature erythroid cells and sustains red blood cells expansion.Haematologica2022
35550257Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.Mol Cell2022
35504865Correction: An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA receptor.Cell Death Dis2022
35436993An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA<sub>A</sub> receptor.Cell Death Dis2022
35565457Upregulation of the Mevalonate Pathway through EWSR1-FLI1/EGR2 Regulatory Axis Confers Ewing Cells Exquisite Sensitivity to Statins.Cancers (Basel)2022
36265118Molecular Characterization of Circulating Tumor DNA in Pediatric Rhabdomyosarcoma: A Feasibility Study.JCO Precis Oncol2022
36054452Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma.J Immunother Cancer2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
33326106Ewing Sarcoma PDX Models.Methods Mol Biol2021
33930311STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma.Cancer Cell2021
34021002Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.Cancer Discov2021
34009296ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion.Nucleic Acids Res2021
34341072Unraveling Ewing Sarcoma Tumorigenesis Originating from Patient-Derived Mesenchymal Stem Cells.Cancer Res2021
34050156Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.Nat Commun2021
34134982Longitudinal high-resolution imaging through a flexible intravital imaging window.Sci Adv2021
32341579Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.Nat Med2020
32049009Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution.Cell Rep2020
31888889Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death.Cancer Res2020
32934208Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity.Nat Commun2020
32881892Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.PLoS One2020
32164354High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.Cancers (Basel)2020
31421907STAG Mutations in Cancer.Trends Cancer2019
31668005Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis.EMBO Rep2019
31708437Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors.Cancer Cell2019
31577941ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma.Cell Rep2019
31511524Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.Nat Commun2019
29321660Activated ALK signals through the ERK-ETV5-RET pathway to drive neuroblastoma oncogenesis.Oncogene2018
29854321Correction: Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation.Oncotarget2018
30093639Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.Nat Commun2018
29977059Ewing sarcoma.Nat Rev Dis Primers2018
27375017EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma.Oncogene2017
28134926DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.Nat Med2017
29141209High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors.Cell Rep2017
28740262Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.Nat Genet2017
27760381High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.Gene2017
27191748Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model.Oncotarget2017
26818002The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation.Nat Commun2016
27283898Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation.Oncotarget2016
26214589Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite.Nat Genet2015
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Institut Curie Hospital
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SIREDO Oncology Center, Institut Curie Hospital, and Universite de Paris
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National Cancer Institute, National Institutes of Health
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National Cancer Institute
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Julien Masliah-Planchon
Curie Institute Hospital Group
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Poul H Sorensen
British Columbia Cancer Research Centre
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Paul Fr??neaux
Institut Curie
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Elaine Del Nery
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Smita Bhatia
Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham
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Emmanuel Barillot
Institut Curie, Universite PSL
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Jean Michon
Institut Curie
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Markus Metzler
University Hospital Erlangen
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Beat W Sch??fer
Department of Oncology and Children's Research Center, University Children's Hospital
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Release 1.2