Author details

Full Name

Santhi K Ganesh

Affiliation

ORCID

Career Start Year

2001

Papers

104

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37131171	Placental transcriptome analysis of hypertensive pregnancies identifies distinct gene expression profiles of preeclampsia superimposed on chronic hypertension.		2023
37910504	Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure.	Cell Rep	2023
37716346	mtPGS: Leverage multiple correlated traits for accurate polygenic score construction.		2023
37979122	Advancements in the Genetics of Spontaneous Coronary Artery Dissection.		2023
36655558	Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.		2023
34476477	Molecular genetic evaluation of pediatric renovascular hypertension due to renal artery stenosis and abdominal aortic coarctation in neurofibromatosis type 1.	Hum Mol Genet	2022
36374587	Fibromuscular Dysplasia and Abdominal Aortic Aneurysms Are Dimorphic Sex-Specific Diseases With Shared Complex Genetic Architecture.	Circ Genom Precis Med	2022
36367690	Phospholipase CÎµ insufficiency causes ascending aortic aneurysm and dissection.	Am J Physiol Heart Circ Physiol	2022
36103205	Burden of Rare Genetic Variants in Spontaneous Coronary Artery Dissection With High-risk Features.	JAMA Cardiology	2022
35762247	Letter to the Editor Regarding Lavanya et al. A patient with a novel pathogenic variant in COL5A1 exhibiting prominent vascular and cardiac features.	Am J Med Genet A	2022
36265953	Canadian Spontaneous Coronary Artery Dissection Cohort Study: 3-Year Outcomes.	J Am Coll Cardiol	2022
36265936	Differences in Demographics and Outcomes Between Men and WomenÂ With Spontaneous CoronaryÂ Artery Dissection.	JACC: Cardiovascular Interventions	2022
33739371	Current progress in clinical, molecular, and genetic aspects of adult fibromuscular dysplasia.	Cardiovasc Res	2022
35234888	Genetic and clinical determinants of abdominal aortic diameter: genome-wide association studies, exome array data and Mendelian randomization study.	Hum Mol Genet	2022
35149163	Histologic and morphologic character of pediatric abdominal aortic developmental coarctation and hypoplasia.	Journal of Vascular Surgery	2022
35092149	Spontaneous coronary artery dissection is infrequent in individuals with heritable thoracic aortic disease despite partially shared genetic susceptibility.	American Journal of Medical Genetics, Part A	2022
34488438	Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease.	Hypertension	2021
32265488	Hemoglobin and erythrocyte count are independently and positively associated with arterial stiffness in a community-based study.	Journal of Human Hypertension	2021
32276022	Histologic and morphologic character of pediatric renal artery occlusive disease.	Journal of Vascular Surgery	2021
33693786	An Asian-specific MPL genetic variant alters JAK-STAT signaling and influences platelet count in the population.	Hum Mol Genet	2021
34110898	FMD and SCAD: Sex-Biased Arterial Diseases With Clinical and Genetic Pleiotropy.	Circulation Research	2021
34265237	Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm.	Am J Hum Genet	2021
32531060	Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia.	Cardiovasc Res	2021
34835015	SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism.	Viruses	2021
34652974	Spontaneous Coronary Artery Dissection: An Underdiagnosed Clinical Entity-A Primer for Cardiac Imagers.	Radiographics	2021
32938213	A Novel Recurrent <i>COL5A1</i> Genetic Variant Is Associated With a Dysplasia-Associated Arterial Disease Exhibiting Dissections and Fibromuscular Dysplasia.	Arterioscler Thromb Vasc Biol	2020
32223311	Hypertension induces glomerulosclerosis in phospholipase C-Îµ1 deficiency.	Am J Physiol Renal Physiol	2020
32276020	Surgical management of pediatric renin-mediated hypertension secondary to renal artery occlusive disease and abdominal aorticÂ coarctation.	Journal of Vascular Surgery	2020
32887874	Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction.	Nat Commun	2020
33230299	Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits.	Nat Genet	2020
31200039	The Association of Intracranial Aneurysms in Women with Renal Artery Aneurysms.	Annals of Vascular Surgery	2019
31712416	The in vivo endothelial cell translatome is highly heterogeneous across vascular beds.	Proc Natl Acad Sci U S A	2019
31869403	Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.	PLoS Genet	2019
30648921	First International Consensus on the diagnosis and management of fibromuscular dysplasia.	Vasc Med	2019
30640867	First international consensus on the diagnosis and management of fibromuscular dysplasia.	J Hypertens	2019
30698711	Canadian spontaneous coronary artery dissection cohort study: in-hospital and 30-day outcomes.	Eur Heart J	2019
29472380	Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association.	Circulation	2018
29905378	Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.	Am J Hematol	2018
27939641	Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease.	Am J Hum Genet	2017
28348047	Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians.	Circ Cardiovasc Genet	2017
28541271	Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve.	Nat Commun	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017
29083407	Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.	Nat Genet	2017
29062018	IFN-Î³ and TNF-Î± synergism may provide a link between psoriasis and inflammatory atherogenesis.	Scientific Reports	2017
28017375	Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.	Am J Hum Genet	2017
27588453	Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.	Am J Hum Genet	2016
27346689	Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.	Am J Hum Genet	2016
27346686	Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.	Am J Hum Genet	2016
27346685	Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.	Am J Hum Genet	2016
26804218	Pediatric nonaortic arterial aneurysms.	Journal of Vascular Surgery	2016