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Author Details

David J H Shih
University of Texas MD Anderson Cancer Center Houston
2009
46
32
PMIDPaper TitleJournal TitlePublished Year
35141022Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer.Am J Cancer Res2022
35176131CNGPLD: case-control copy-number analysis using Gaussian process latent difference.Bioinformatics2022
34066883A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches.Int J Mol Sci2021
32286280Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.Nat Commun2020
32612833Role of DNA repair defects in predicting immunotherapy response.Biomark Res2020
32109374Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer.Cancer Cell2020
32286303Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas.Nat Commun2020
32577620The Tale of CHD4 in DNA Damage Response and Chemotherapeutic Response.J Cancer Res Cell Ther2019
29474906A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.Cell2018
30019219Heterogeneity within the PF-EPN-B ependymoma subgroup.Acta Neuropathol2018
29856958A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.Cell2018
28609654Intertumoral Heterogeneity within Medulloblastoma Subgroups.Cancer Cell2017
28394352Spatial heterogeneity in medulloblastoma.Nat Genet2017
28504719Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.Oncogene2017
26760213Divergent clonal selection dominates medulloblastoma at recurrence.Nature2016
26976201Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.Lancet Oncol2016
25336695Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.Clin Cancer Res2015
25957288Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.Clin Cancer Res2015
25739120Mechanism of action and therapeutic efficacy of Aurora kinase B inhibition in MYC overexpressing medulloblastoma.Oncotarget2015
24493713Cytogenetic prognostication within medulloblastoma subgroups.J Clin Oncol2014
25539912WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma.Acta Neuropathol Commun2014
25584369Response.J Neurosurg2014
25245477Gene-expression profiling elucidates molecular signaling networks that can be therapeutically targeted in vestibular schwannoma.J Neurosurg2014
25043047Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma.Nature2014
25150496The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.Nat Med2014
25136069Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity.Cancer Res2014
24831600MRI surrogates for molecular subgroups of medulloblastoma.AJNR Am J Neuroradiol2014
24616042Duration of the pre-diagnostic interval in medulloblastoma is subgroup dependent.Pediatr Blood Cancer2014
24553142Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.Nature2014
24651015Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.Cancer Cell2014
23184418Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.Acta Neuropathol2013
24067506Targeting sonic hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-like kinases.Cancer Res2013
24092238MyoD is a tumor suppressor gene in medulloblastoma.Cancer Res2013
24140199Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis.Lancet Oncol2013
24174164TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.Acta Neuropathol2013
23852537Notch1-induced brain tumor models the sonic hedgehog subgroup of human medulloblastoma.Cancer Res2013
23835706Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma.J Clin Oncol2013
22057785Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples.Acta Neuropathol2012
23019410High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis.Neoplasia2012
22832583Dissecting the genomic complexity underlying medulloblastoma.Nature2012
22832581Subgroup-specific structural variation across 1,000 medulloblastoma genomes.Nature2012
22265402Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.Cell2012
22358458Subgroup-specific alternative splicing in medulloblastoma.Acta Neuropathol2012
22343890Clonal selection drives genetic divergence of metastatic medulloblastoma.Nature2012
21681522Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct.Acta Neuropathol2011
19962671Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors.Cancer Cell2009
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Stephen C Mack
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Livia Garzia
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Claudia C Faria
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Luca Massimi
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Xin Wang
The Chinese University of Hong Kong, Prince of Wales Hospital
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Xiaochong Wu
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David Malkin
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Release 1.2