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Author Details

Alexander Marson
Gladstone-UCSF Institute of Genomic Immunology
2004
79
40
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36008610High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails.Nat Biotechnol2023
37547023The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation.bioRxiv2023
37648854CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.Nature2023
37503101Non-coding sequence variation reveals fragility within interleukin 2 feedback circuitry and shapes autoimmune disease risk.bioRxiv2023
36993276Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling.bioRxiv2023
37147433Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes.Nat Biomed Eng2023
36914891A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.Nat Immunol2023
35077396Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage.J Clin Invest2022
35365639A functional map of HIV-host interactions in primary human T cells.Nat Commun2022
35817986Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks.Nat Genet2022
35355021Obesity alters pathology and treatment response in inflammatory disease.Nature2022
36002574RASA2 ablation in T cells boosts antigen sensitivity and long-term function.Nature2022
36127419Advancing T cell-based cancer therapy with single-cell technologies.Nat Med2022
36350984Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies.Sci Transl Med2022
35977472A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity.Cell Rep Med2022
35217172Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression.Mol Cell Proteomics2022
35143305CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells.Science2022
35113687CRISPR activation and interference screens decode stimulation responses in primary human T cells.Science2022
35110421ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8<sup>+</sup> T Cell Effector and Memory Responses.J Immunol2022
35104875CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells.Nucleic Acids Res2022
33351785TCF-1 regulates HIV-specific CD8+ T cell expansion capacity.JCI Insight2021
33883145XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment.Sci Adv2021
33682796Epithelial miR-141 regulates IL-13-induced airway mucus production.JCI Insight2021
33624747PICS2: next-generation fine mapping via probabilistic identification of causal SNPs.Bioinformatics2021
33592174Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis.Cell2021
33497260Genetic Disease and Therapy.Annu Rev Pathol2021
34970966Robust T cell activation requires an eIF3-driven burst in T cell receptor translation.Elife2021
34188205Genome editing to define the function of risk loci and variants in rheumatic disease.Nat Rev Rheumatol2021
34077734Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering.Cell Rep2021
34088745Abcc1 and Ggt5 support lymphocyte guidance through export and catabolism of S-geranylgeranyl-l-glutathione.Sci Immunol2021
33951726Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.J Exp Med2021
32511497Test performance evaluation of SARS-CoV-2 serological assays.medRxiv2020
32084337A Quantitative Genetic Interaction Map of HIV Infection.Mol Cell2020
31819258Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency.Nat Biotechnol2020
33057163Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.Nat Biotechnol2020
32855547Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.Nat Biotechnol2020
32989329Functional CRISPR dissection of gene networks controlling human regulatory T cell identity.Nat Immunol2020
32643825Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR).EMBO J2020
32868928NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting.Nat Immunol2020
32499641CRISPR screen in regulatory T cells reveals modulators of Foxp3.Nature2020
32539073Layilin augments integrin activation to promote antitumor immunity.J Exp Med2020
30559373CRISPR-Cas9 genome engineering of primary CD4<sup>+</sup> T cells for the interrogation of HIV-host factor interactions.Nat Protoc2019
31757834Helios enhances the preferential differentiation of human fetal CD4<sup>+</sup> naïve T cells into regulatory T cells.Sci Immunol2019
31852848Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues.JCI Insight2019
31359007Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.Nat Biotechnol2019
31182835Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function.Nat Biomed Eng2019
31433990miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival.Cell Rep2019
31204070The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.Immunity2019
30709738A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.Immunity2019
30643267Thymic regulatory T cells arise via two distinct developmental programs.Nat Immunol2019
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Collaborators

Theodore L Roth
Stanford University
Co-authored papers 22
Chun Jimmie Ye
University of California san francisco
Co-authored papers 13
Dimitre R Simeonov
University of California San Francisco
Co-authored papers 13
Kathrin Schumann
Institute for Medical Microbiology, Technical University of Munich (TUM)
Co-authored papers 12
Eric Shifrut
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 12
Jonathan M Woo
University of California san francisco
Co-authored papers 11
David N Nguyen
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 11
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 9
Joseph B Hiatt
Fred Hutchinson Cancer Center
Co-authored papers 9
Brian R Shy
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 8
Youjin V Lee
University of Chicago
Co-authored papers 6
Jennifer A Doudna
Innovative Genomics Institute, University of California berkeley
Co-authored papers 6
Victoria Tobin
California Institute of Technology
Co-authored papers 6
Judd F Hultquist
Northwestern University Feinberg School of Medicine
Co-authored papers 6
Jason G Cyster
University of California san francisco
Co-authored papers 5
Ansuman T Satpathy
Stanford University
Co-authored papers 5
Ruby Yu
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 5
Jacob E Corn
Co-authored papers 4
Sagar P Bapat
The Salk Institute for Biological Studies
Co-authored papers 4
William J Greenleaf
Stanford University
Co-authored papers 4
Julia Carnevale
University of California san francisco
Co-authored papers 4
David A Hafler
Yale School of Medicine, Yale School of Public Health
Co-authored papers 4
Maxwell R Mumbach
Broad Institute of MIT and Harvard
Co-authored papers 4
Cody T Mowery
University of California san francisco
Co-authored papers 4
Howard Y Chang
Center for Personal Dynamic Regulomes, Stanford University
Co-authored papers 4
Michelle Nguyen
School of Medicine Stanford University
Co-authored papers 3
Mark J Daly
Massachusetts General Hospital
Co-authored papers 3
Lindsey A Criswell
Co-authored papers 3
Antonia E Gallman
Yale University School of Medicine
Co-authored papers 3
Zachary Steinhart
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 3
Release 1.2