Author details

Full Name

Victor Koteliansky

Affiliation

ORCID

Career Start Year

1974

Papers

226

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34328499	Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.	Journal of Cell Biology	2021
33589614	Identification of a long non-coding RNA regulator of liver carcinoma cell survival.	Cell Death Dis	2021
32577433	Liver-Specific siRNA-Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis.	Molecular Therapy - Methods and Clinical Development	2020
31855834	InÂ Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation.	Mol Ther Nucleic Acids	2020
32968084	Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes.	Sci Rep	2020
31248772	Synthesis and biological evaluation of PSMA-targeting paclitaxel conjugates.	Bioorganic and Medicinal Chemistry Letters	2019
30904185	Synthesis and biological evaluation of Doxorubicin-containing conjugate targeting PSMA.	Bioorganic and Medicinal Chemistry Letters	2019
31204997	Liquid-crystal organization of liver tissue.	eLife	2019
31056242	Corrigendum to 'Synthesis and biological evaluation of Doxorubicin-containing conjugate targeting PSMA' [Bioor. Med. Chem. Lett. 29/10 (2019) 1246-1255].	Bioorganic and Medicinal Chemistry Letters	2019
29542689	Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.	Nature	2018
29377001	Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.	Nature Chemical Biology	2018
29131148	Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.	Nature Biotechnology	2017
28890072	Large-Scale Quantitative Proteomics Identifies the Ubiquitin Ligase Nedd4-1 as an Essential Regulator of Liver Regeneration.	Dev Cell	2017
28624207	Identification of Novel Fibrosis Modifiers by InÂ Vivo siRNA Silencing.	Molecular Therapy - Nucleic Acids	2017
28700576	Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration.	Nature	2017
26707202	N6-Methylated Adenosine in RNA: From Bacteria to Humans.	Journal of Molecular Biology	2016
27440073	Identification of Novel Small-Molecule ASGP-R Ligands.		2016
26887438	Small-molecule PSMA ligands. Current state, SAR and perspectives.	Journal of Drug Targeting	2016
26829318	Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo.	Nat Biotechnol	2016
26780833	Synthesis, isomerization and biological activity of novel 2-selenohydantoin derivatives.	Bioorganic and Medicinal Chemistry	2016
27318030	lncRNA in the liver: Prospects for fundamental research and therapy by RNA interference.		2016
27462152	Lipid nanoparticles for targeted siRNA delivery - going from bench to bedside.	International Journal of Nanomedicine	2016
27449617	mRNA-Based TherapeuticsÂ - Advances and Perspectives.	Biochemistry (Moscow)	2016
26658687	RNAi-nanoparticulate manipulation of gene expression as a new functional genomics tool in the liver.	Journal of Hepatology	2016
26585933	A Comprehensive Insight into the Chemical Space and ADME Features of Small Molecule NS5A Inhibitors.	Current Topics in Medicinal Chemistry	2016
26585932	In Silico Approaches to the Design of NS5A Inhibitors.	Current Topics in Medicinal Chemistry	2016
24950695	Silencing of CCR2 in myocarditis.	European Heart Journal	2015
25416068	Control of hepatocyte proliferation and survival by Fgf receptors is essential for liver regeneration in mice.	Gut	2015
25937276	Regulation of liver metabolism by the endosomal GTPase Rab5.	Cell Rep	2015
26220182	Identification of siRNA delivery enhancers by a chemical library screen.	Nucleic Acids Research	2015
24516150	Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.	Proceedings of the National Academy of Sciences of the United States of America	2014
25355493	Loss of Î±-catenin elicits a cholestatic response and impairs liver regeneration.	Sci Rep	2014
24681508	Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.	Nature Biotechnology	2014
24992693	The roles of individual mammalian argonautes in RNA interference in vivo.	PLoS One	2014
24844798	Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.	Nature Communications	2014
24844558	Knockdown and knockout of Î²1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling.	Nature Communications	2014
23409044	MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling.	PLoS One	2013
23792630	Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape.	Nature Biotechnology	2013
23747253	MICU1 controls both the threshold and cooperative activation of the mitochondrial CaÂ²âº uniporter.	Cell Metab	2013
23040070	Silencing of lipid metabolism genes through IRE1Î±-mediated mRNA decay lowers plasma lipids in mice.		2012
22308361	Origins of tumor-associated macrophages and neutrophils.	Proceedings of the National Academy of Sciences of the United States of America	2012
22291093	IRE1Î± activation protects mice against acetaminophen-induced hepatotoxicity.	Journal of Experimental Medicine	2012
22622570	Rab5 is necessary for the biogenesis of the endolysosomal system in vivo.	Nature	2012
22326225	The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals.		2012
22611156	Treatment of erythropoietin deficiency in mice with systemically administered siRNA.	Blood	2012
23344621	Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.	Molecular Therapy - Nucleic Acids	2012
21685886	Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.	Nature	2011
21983520	Therapeutic siRNA silencing in inflammatory monocytes in mice.	Nature Biotechnology	2011
20461061	Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.	Molecular Therapy	2010
20686566	From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.	Nature	2010