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Author Details

Ga??lle Legube
CNRS, Universite de Toulouse
2002
58
39
PMIDPaper TitleJournal TitlePublished Year
37974007Author Correction: Chromatin compartmentalization regulates the response to DNA damage.Nature2023
37853125Chromatin compartmentalization regulates the response to DNA damage.Nature2023
37833263Chromatin organization drives the search mechanism of nuclear factors.Nat Commun2023
35333579Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor.Sci Adv2022
35440629A POLD3/BLM dependent pathway handles DSBs in transcribed chromatin upon excessive RNA:DNA hybrid accumulation.Nat Commun2022
36002001Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.Mol Cell2022
36215697Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism.EMBO J2022
32840796Analyzing Homologous Recombination at a Genome-Wide Level.Methods Mol Biol2021
33597753Loop extrusion as a mechanism for formation of DNA damage repair foci.Nature2021
33837288R-loops as Janus-faced modulators of DNA repair.Nat Cell Biol2021
34111758Repair of DNA double-strand breaks in RNAPI- and RNAPII-transcribed loci.DNA Repair (Amst)2021
31401119The Secret Life of Chromosome Loops upon DNA Double-Strand Break.J Mol Biol2020
31873295m<sup>6</sup>A RNA modification as a new player in R-loop regulation.Nat Genet2020
32154266Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox.Front Mol Biosci2020
30604748Genome editing in primary cells and in vivo using viral-derived Nanoblades loaded with Cas9-sgRNA ribonucleoproteins.Nat Commun2019
31395742A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair.Genes Dev2019
31331819Non-canonical DNA/RNA structures during Transcription-Coupled Double-Strand Break Repair: Roadblocks or Bona fide repair intermediates?DNA Repair (Amst)2019
30898334A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks.Trends Genet2019
29544533Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution.Genome Biol2018
30464262DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.Nature2018
30270107Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures.Mol Cell2018
29416069Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations.Nat Commun2018
28068556Organizing DNA repair in the nucleus: DSBs hit the road.Curr Opin Cell Biol2017
28363678Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care.J Mol Biol2017
28263325Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes.Nat Struct Mol Biol2017
29099269A meeting at risk: Unrepaired DSBs go for broke.Nucleus2017
28572115Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.J Cell Biol2017
28624372Taming Tricky DSBs: ATM on duty.DNA Repair (Amst)2017
27153538The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.Mol Cell2016
26578593DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.Nucleic Acids Res2016
27314089A TAD closer to ATM.Mol Cell Oncol2016
25593309Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.Genes Dev2015
26586426Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks.Cell Rep2015
26007308Proton-induced direct and indirect damage of plasmid DNA.Radiat Environ Biophys2015
25675367DNA double strand break repair pathway choice: a chromatin based decision?Nucleus2015
24362840Quantitation of DNA double-strand break resection intermediates in human cells.Nucleic Acids Res2014
24931610SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability.Cell Rep2014
24504477Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification.Nat Protoc2014
24658350Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.Nat Struct Mol Biol2014
24336221Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break.Nat Struct Mol Biol2014
23609533DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis.J Cell Biol2013
22275873Cohesin protects genes against γH2AX Induced by DNA double-strand breaks.PLoS Genet2012
21947284Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection.Mol Cell Biol2011
20360682High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.EMBO J2010
20802485Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.Nat Struct Mol Biol2010
20714222Deciphering the chromatin landscape induced around DNA double strand breaks.Cell Cycle2010
20548951The E1A-associated p400 protein modulates cell fate decisions by the regulation of ROS homeostasis.PLoS Genet2010
16547175X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila.Genes Dev2006
17189182To die or not to die: a HAT trick.Mol Cell2006
16601686Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression.EMBO J2006
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The University of Texas at Austin
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Max Planck Institute of Immunobiology and Epigenetics
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Jacques C??t??
Centre Hospitalier Universitaire (CHU) de Quebec-Universite Laval Research Center
Co-authored papers 2
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CNRS, Universite de Toulouse
Co-authored papers 2
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Brandeis University
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University of California san francisco
Co-authored papers 2
Martin J Lercher
Institute for Computer Science, Heinrich Heine University
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Zurich University Hospital
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University of Texas at Austin
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CRUK MRC Oxford Institute for Radiation Oncology, University of Oxford
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Dana-Farber Cancer Institute
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College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
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Dana-Farber Cancer Institute
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Thomas Helleday
The University of Sheffield
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Zdenko Herceg
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John G Doench
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Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
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Jie Bian
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University of Laval
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Release 1.2