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Author Details

Adrian Francis Stewart
Center for Molecular and Cellular Bioengineering, Technische Universitat Dresden
1976
202
84
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36690694The Rad52 SSAP superfamily and new insight into homologous recombination.Commun Biol2023
34806773Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes.EMBO J2022
35064075Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells.Life Sci Alliance2022
35137160Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation.Nucleic Acids Res2022
34792175Improved dsDNA recombineering enables versatile multiplex genome engineering of kilobase-scale sequences in diverse bacteria.Nucleic Acids Res2022
34860830MLL1 is required for maintenance of intestinal stem cells.PLoS Genet2021
32439762MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation.Development2020
33119745RedEx: a method for seamless DNA insertion and deletion in large multimodular polyketide synthase gene clusters.Nucleic Acids Res2020
32873602Selection and Characterization of Mutants Defective in DNA Methylation in Neurospora crassa.Genetics2020
30447257Expressing cytotoxic compounds in Escherichia coli Nissle 1917 for tumor-targeting therapy.Res Microbiol2019
30842216The Set1 complex is dimeric and acts with Jhd2 demethylation to convey symmetrical H3K4 trimethylation.Genes Dev2019
30953756Proteomic navigation using proximity-labeling.Methods2019
30315824Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.Exp Hematol2019
30590919Enhanced Heterologous Spinosad Production from a 79-kb Synthetic Multioperon Assembly.ACS Synth Biol2019
29240926ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes.Nucleic Acids Res2018
29916805The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.Elife2018
30194327Human adenovirus type 17 from species D transduces endothelial cells and human CD46 is involved in cell entry.Sci Rep2018
30504434Kmt2b conveys monovalent and bivalent H3K4me3 in mouse spermatogonial stem cells at germline and embryonic promoters.Development2018
30355503KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes.Cell Rep2018
29348130SETD1A protects HSCs from activation-induced functional decline in vivo.Blood2018
29323282MLL2 conveys transcription-independent H3K4 trimethylation in oocytes.Nat Struct Mol Biol2018
29272442ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes.Nucleic Acids Res2018
27165042The enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice.Chromosoma2017
28257711DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization.Cell Stem Cell2017
28467833Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029.ACS Chem Biol2017
29241531lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1.Cell Rep2017
28538186An Engineered Virus Library as a Resource for the Spectrum-wide Exploration of Virus and Vector Diversity.Cell Rep2017
28723559KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.Cell Rep2017
28619824<i>Setd1b</i>, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.Development2017
28609655MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.Cancer Cell2017
28582546The contribution of homology arms to nuclease-assisted genome engineering.Nucleic Acids Res2017
26883360Mutation of cancer driver MLL2 results in transcription stress and genome instability.Genes Dev2016
27641306DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization.Cell Stem Cell2016
27779405Regular Nanoscale Protein Patterns via Directed Adsorption through Self-Assembled DNA Origami Masks.ACS Appl Mater Interfaces2016
27708411DNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions.Sci Rep2016
27364376"Cre/loxP plus BAC": a strategy for direct cloning of large DNA fragment and its applications in Photorhabdus luminescens and Agrobacterium tumefaciens.Sci Rep2016
27440201msVolcano: A flexible web application for visualizing quantitative proteomics data.Proteomics2016
27254463RecET direct cloning and Redαβ recombineering of biosynthetic gene clusters, large operons or single genes for heterologous expression.Nat Protoc2016
27216209RAC-tagging: Recombineering And Cas9-assisted targeting for protein tagging and conditional analyses.Sci Rep2016
27485686Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs, and Increased Anxiety.Neuropsychopharmacology2016
27095488Room temperature electrocompetent bacterial cells improve DNA transformation and recombineering efficiency.Sci Rep2016
25539914A new recombineering system for Photorhabdus and Xenorhabdus.Nucleic Acids Res2015
26280580RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome.J Clin Invest2015
26252244Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex.PLoS Biol2015
26459865Direct cloning and heterologous expression of the salinomycin biosynthetic gene cluster from Streptomyces albus DSM41398 in Streptomyces coelicolor A3(2).Sci Rep2015
26271032A Single-Strand Annealing Protein Clamps DNA to Detect and Secure Homology.PLoS Biol2015
27135800Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.Cell Syst2015
25834037Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.J Neurosci2015
25803509Lambda red mediated gap repair utilizes a novel replicative intermediate in Escherichia coli.PLoS One2015
25431426Stimulation of oligonucleotide-directed gene correction by Redβ expression and MSH2 depletion in human HT1080 cells.Mol Cells2015
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Collaborators

University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Co-authored papers 19
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 12
Max Plank Institute of Molecular Cell Biology and Genetics
Co-authored papers 9
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 9
Technische Universitaet Dresden
Co-authored papers 8
Co-authored papers 6
Wellcome Trust Sanger Institute
Co-authored papers 5
College of Chemistry and Chemical Engineering, Lanzhou University
Co-authored papers 5
Technische Universitaet Dresden
Co-authored papers 5
Center for Molecular and Cellular Bioengineering, University of Technology Dresden
Co-authored papers 5
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 4
Co-authored papers 4
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 4
Radboud Institute for Molecular Science, Radboud University
Co-authored papers 4
The Wellcome Trust Sanger Institute
Co-authored papers 4
Medical Faculty and University Hospital Carl Gustav Carus
Co-authored papers 3
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 3
Aix Marseille University, CNRS, Turing Center for Living Systems
Co-authored papers 3
Faculty of Medicine and University Hospital Carl Gustav Carus
Co-authored papers 3
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Clinic for Plastic, Otto von Guericke University
Co-authored papers 2
Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)
Co-authored papers 2
University of Michigan ann arbor
Co-authored papers 2
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
CSIR-Institute of Genomics & Integrative Biology
Co-authored papers 2
University of California davis
Co-authored papers 2
Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 2
McDermott Center for Human Growth and Development.
Co-authored papers 2
Institute of Neurophysiology, University of Cologne
Co-authored papers 2