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Author Details

Sharad K Verma
Johns Hopkins University
1998
27
13
PMIDPaper TitleJournal TitlePublished Year
31793149Funding community collaboration to develop effective therapies for neurofibromatosis type 1 tumors.EMBO Mol Med2020
32642737Assessing interobserver variability and accuracy in the histological diagnosis and classification of cutaneous neurofibromass.Neurooncol Adv2019
31836719Engaging a community to enable disease-centric data sharing with the NF Data Portal.Sci Data2019
29893754Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells.Sci Data2018
29987133Clinical trial design for cutaneous neurofibromas.Neurology2018
29987131The biology of cutaneous neurofibromas: Consensus recommendations for setting research priorities.Neurology2018
29987132Considerations for development of therapies for cutaneous neurofibroma.Neurology2018
29987130Cutaneous neurofibromas: Current clinical and pathologic issues.Neurology2018
29987129Creating a comprehensive research strategy for cutaneous neurofibromas.Neurology2018
25421686Recent progress in the discovery of epigenetic inhibitors for the treatment of cancer.Methods Mol Biol2015
25732793Inhibition of the histone lysine methyltransferase EZH2 for the treatment of cancer.Curr Top Med Chem2015
24304166Long residence time inhibition of EZH2 in activated polycomb repressive complex 2.ACS Chem Biol2014
25253781A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation.Mol Cancer Ther2014
24553142Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.Nature2014
23680150EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.Cancer Cell2013
24047271Recent progress in the discovery of small-molecule inhibitors of the HMT EZH2 for the treatment of cancer.Future Med Chem2013
22904200Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens.J Biomol Screen2012
24900432Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2.ACS Med Chem Lett2012
23051747EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations.Nature2012
200051022,3,5-Trisubstituted pyridines as selective AKT inhibitors. Part II: Improved drug-like properties and kinase selectivity from azaindazoles.Bioorg Med Chem Lett2010
20006500Tetrasubstituted pyridines as potent and selective AKT inhibitors: Reduced CYP450 and hERG inhibition of aminopyridines.Bioorg Med Chem Lett2010
15808450Substituted aminobenzimidazole pyrimidines as cyclin-dependent kinase inhibitors.Bioorg Med Chem Lett2005
12515481Asymmetric synthesis of the carbapenam core from serine.J Org Chem2003
11846680Hydroxylated pyrrolidines. Enantiospecific synthesis of all-cis 2,3,4,5-substituted pyrrolidine derivatives from serine.J Org Chem2002
11112576Synthesis of angular triquinanes from 1-Alkynylbicyclo[3.2. 0]hept-2-en-7-ones. A tandem alkoxy-cope ring Expansion/Transannular ring closure reaction.J Org Chem2000
10843620Oxy-cope rearrangements of bicyclo[3.2.0]heptenones. Synthesis of bicyclo[4.2.1]non-1(4)-en-6-ones and bicyclo[5.2. 1]dec-1(10)-en-5-ones.J Org Chem2000
11672312Cyclobutenone-Based Syntheses of Polyquinanes and Bicyclo[6.3.0]undecanes by Tandem Anionic Oxy-Cope Reactions. Total Synthesis of (+/-)-Precapnelladiene.J Org Chem1998
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Collaborators

Jaishri O Blakeley
Johns Hopkins University
Co-authored papers 9
Kristin K Brown
Co-authored papers 2
Marigo Stathis
Johns Hopkins University School of Medicine
Co-authored papers 2
Annette Bakker
Children's Tumor Foundation
Co-authored papers 2
Steven A McCarroll
Co-authored papers 2
Justin Guinney
University of Washington
Co-authored papers 2
Brigitte C Widemann
Co-authored papers 2
Anat Stemmer-Rachamimov
Massachusetts General Hospital
Co-authored papers 2
Rakesh Kumar
Rutgers New Jersey Medical School
Co-authored papers 2
Sara J C Gosline
Pacific Northwest National Laboratory (PNNL)
Co-authored papers 2
Salvatore La Rosa
university of massachusetts amherst Chan Medical School
Co-authored papers 2
Cynthia Hawkins
The Hospital for Sick Children
Co-authored papers 1
Martin Sill
Co-authored papers 1
Claudia C Faria
Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN)
Co-authored papers 1
Martin Hirst
University of British Columbia
Co-authored papers 1
Roxann G Ingersoll
Mc-Kusick-Nathans Institute of Genetic Medicine, Johns Hopkins
Co-authored papers 1
Huriye Seker-Cin
Institute of Pathology, Heidelberg University Hospital
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James T Rutka
Hospital for Sick Children
Co-authored papers 1
Marc Ferrer
National Institutes of Health, National Center for Advancing Translational Sciences
Co-authored papers 1
Daniel W Fults
Co-authored papers 1
Joanna J Phillips
University of California san francisco
Co-authored papers 1
Uri Tabori
Co-authored papers 1
Margaret R Wallace
UF Genetics Institute, University of Florida
Co-authored papers 1
Marco Gallo
Co-authored papers 1
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 1
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Annie Huang
Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children
Co-authored papers 1
Fausto J Rodriguez
University of California Los Angeles
Co-authored papers 1
William A Weiss
University of California san francisco
Co-authored papers 1
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
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