Author details

Full Name

Ashley M Deacon

Affiliation

Accelero Biostructures Inc., USA XPose Therapeutics Inc.

ORCID

Career Start Year

1996

Papers

161

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33115610	Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.	Prog Biophys Mol Biol	2021
34900730	Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH).	Front Oncol	2021
31306512	Structures of single-layer Î²-sheet proteins evolved from Î²-hairpin repeats.	Protein Sci	2019
27050129	UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.	Acta Crystallogr D Struct Biol	2016
26940874	Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome.	J Biol Chem	2016
26829219	Dlx5 Homeodomain:DNA Complex: Structure, Binding and Effect of Mutations Related to Split Hand and Foot Malformation Syndrome.	J Mol Biol	2016
27062925	A Distinct Type of Pilus from the Human Microbiome.	Cell	2016
25825768	Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.	Proc Natl Acad Sci U S A	2015
26374125	Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains.	mBio	2015
26416531	Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket.	J Struct Biol	2015
26177955	Cofactor-induced reversible folding of Flavodoxin-4 from Lactobacillus acidophilus.	Protein Sci	2015
23852666	Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site.	Proteins	2014
25465128	Structure-guided functional characterization of DUF1460 reveals a highly specific NlpC/P60 amidase family.	Structure	2014
25288771	The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.	Proc Natl Acad Sci U S A	2014
25286848	Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications.	Acta Crystallogr D Biol Crystallogr	2014
25197798	Structural insights into the recognition of phosphopeptide by the FHA domain of kanadaptin.	PLoS One	2014
25349992	Cell fate regulation governed by a repurposed bacterial histidine kinase.	PLoS Biol	2014
25044324	Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake.	Protein Sci	2014
24888348	Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome.	Protein Sci	2014
24051416	Structures of a bifunctional cell wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 DL-endopeptidase.	J Mol Biol	2014
24174223	Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.	Proteins	2014
23572527	Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.	J Biol Chem	2013
24123814	Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling.	J Bacteriol	2013
23932593	Branched signal wiring of an essential bacterial cell-cycle phosphotransfer protein.	Structure	2013
22411095	Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.	Proteins	2012
22984442	Structure of a novel winged-helix like domain from human NFRKB protein.	PLoS One	2012
22844465	Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.	PLoS One	2012
22505259	Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.	Acta Crystallogr D Biol Crystallogr	2012
22467785	The structure of Mlc titration factor A (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor.	J Bacteriol	2012
22514186	Adapting federated cyberinfrastructure for shared data collection facilities in structural biology.	J Synchrotron Radiat	2012
22211578	Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization.	Mol Microbiol	2012
21247902	Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor.	J Biol Chem	2011
21799766	Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.	PLoS One	2011
21799754	Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake.	PLoS One	2011
21538547	Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity.	Proteins	2011
21445265	Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein.	PLoS One	2011
21460455	Distributed structure determination at the JCSG.	Acta Crystallogr D Biol Crystallogr	2011
20077512	Genomics, evolution, and crystal structure of a new family of bacterial spore kinases.	Proteins	2010
20836087	The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.	Protein Sci	2010
20869368	Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.	J Mol Biol	2010
20944232	Structure of the Î³-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-Î³-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944231	Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944230	Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved Î±+Î² core domain and an auxiliary C-terminal treble-clef zinc finger.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944229	Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944228	The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944227	Ligands in PSI structures.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944225	Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944224	Structure of Bacteroides thetaiotaomicron BT2081 at 2.05â¿¿Ã¿ resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944223	A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2â¿¿Ã¿ resolution.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010
20944222	Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.	Acta Crystallogr Sect F Struct Biol Cryst Commun	2010

1 - 50 of 161

Ashwani Kumar

Bhabha Atomic Research Centre

Career Start Year 2009

Number of shared co-authors 0

Lester G Carter

Stanford University

Career Start Year 2004

Number of shared co-authors 2

Elena Evdokimova

University of Toronto

Career Start Year 2002

Number of shared co-authors 3

B Martin Hallberg

Karolinska Institutet

Career Start Year 2000

Number of shared co-authors 4

Irina Dementieva

Northwestern University, Feinberg School of Medicine

Career Start Year 1999

Number of shared co-authors 6

Jeffrey B Bonanno

Albert Einstein College of Medicine

Career Start Year 1999

Number of shared co-authors 4

David R Hall

Diamond Light Source Ltd, Harwell Science & Innovation Campus

Career Start Year 1998

Number of shared co-authors 0

Stephen A McMahon

University of St Andrews

Career Start Year 1998

Number of shared co-authors 0

Alexei Savchenko

University of Toronto

Career Start Year 1997

Number of shared co-authors 7

Li-Wei Hung

Los Alamos National Laboratory

Career Start Year 1997

Number of shared co-authors 7

J Michael Sauder

Eli Lilly and Co.

Career Start Year 1996

Number of shared co-authors 4

Zihe Rao

Nankai University

Career Start Year 1995

Number of shared co-authors 5

Orly Dym

Weizmann Institute of Science

Career Start Year 1995

Number of shared co-authors 4

Clemens Vonrhein

Global Phasing Ltd

Career Start Year 1995

Number of shared co-authors 1

Min Zhou

College of Materials Science and Engineering, Hunan University

Career Start Year 1994

Number of shared co-authors 4

Youngchang Kim

Argonne National Laboratory

Career Start Year 1993

Number of shared co-authors 10

Diana R Tomchick

University of Texas Southwestern Medical Center

Career Start Year 1993

Number of shared co-authors 2

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Career Start Year 1989

Number of shared co-authors 6

Liang Tong

Columbia University

Career Start Year 1988

Number of shared co-authors 6

John F Hunt

Columbia University

Career Start Year 1986

Number of shared co-authors 4

Thomas B Acton

Center for Advanced Biotechnology and Medicine, The State University of New Jersey

Career Start Year 1986

Number of shared co-authors 7

Aled M Edwards

University of Toronto

Career Start Year 1984

Number of shared co-authors 7

Stephen K Burley

The State University of New Jersey

Career Start Year 1982

Number of shared co-authors 13

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Career Start Year 1979

Number of shared co-authors 16

Tom Alber

University of California berkeley

Career Start Year 1976

Number of shared co-authors 3

Ivan Rayment

College of Agricultural and Life Sciences, University of Wisconsin-Madison

Career Start Year 1976

Number of shared co-authors 1

Ezra Peisach

The State University of New Jersey

Career Start Year 1975

Number of shared co-authors 1

George N Phillips

Rice University

Career Start Year 1974

Number of shared co-authors 4

Wayne A Hendrickson

Columbia University

Career Start Year 1968

Number of shared co-authors 5

Sung-Hou Kim

University of California berkeley

Career Start Year 1967

Number of shared co-authors 6

row(s) 1 - 30 of 30

Ian A Wilson

The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology

Co-authored papers 127

Scott A Lesley

Merck & Co., Inc.

Co-authored papers 124

Marc-Andr?? Elsliger

Joint Center for Structural Genomics

Co-authored papers 121

Adam Godzik

University of California Riverside

Co-authored papers 120

Mitchell D Miller

Rice University

Co-authored papers 114

Lukasz Jaroszewski

University of California Riverside School of Medicine

Co-authored papers 110

Heath E Klock

Merck & Co., Inc.

Co-authored papers 104

Hsiu-Ju Chiu

Joint Center for Structural Genomics

Co-authored papers 101

Qingping Xu

Argonne National Laboratory

Co-authored papers 99

John Wooley

University of California

Co-authored papers 94

Henry van den Bedem

University of California San Francisco

Co-authored papers 93

Daniel McMullan

Genomics Institute of the Novartis Research Foundation

Co-authored papers 90

Keith O Hodgson

Stanford University

Co-authored papers 90

Andrew T Morse

Co-authored papers 79

Polat Abdubek

Regeneron Pharmaceuticals, Inc.

Co-authored papers 73

Slawomir K Grzechnik

Co-authored papers 71

Mark W Knuth

Joint Center for Structural Genomics

Co-authored papers 67

Ron Reyes

Co-authored papers 67

Herbert L Axelrod

Joint Center for Structural Genomics

Co-authored papers 61

Edward Nigoghossian

Genomics Institute of the Novartis Research Foundation

Co-authored papers 61

Gye Won Han

Bridge Institute, University of Southern California

Co-authored papers 60

Sanjay Krishna

Institute of Science, Banaras Hindu University

Co-authored papers 53

Peter Kuhn

University of Tubingen

Co-authored papers 52

Christopher L Rife

The Joint Center for Structural Genomics, Stanford University

Co-authored papers 50

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Co-authored papers 48

Kevin K Jin

Cardiovascular Institute, Stanford University School of Medicine

Co-authored papers 47

Thomas Clayton

Celgene/Bristol-Myers Squibb Corporation

Co-authored papers 46

Julie Feuerhelm

Co-authored papers 46

Lian Duan

Brown University

Co-authored papers 46

Linda Okach

Co-authored papers 45

1 - 30

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