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Author Details

Julian L Griffin
Cambridge University
1998
319
69
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36326588Pathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer's disease mouse model and risk loci carriers.J Neurochem2023
37084865Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL).Mol Metab2023
37070436Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial.Circulation2023
37128607N-arachidonylglycine is a caloric state-dependent circulating metabolite which regulates human CD4<sup>+</sup>T cell responsiveness.iScience2023
36828894A proposed framework to evaluate the quality and reliability of targeted metabolomics assays from the UK Consortium on Metabolic Phenotyping (MAP/UK).Nat Protoc2023
36305874Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells.J Exp Med2023
35080268Reply.Hepatology2022
35642679Correction to "Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast Cancerâ¿¿Link to Patient Survival, Hormone Receptor Status, and Metabolic Profiling".J Proteome Res2022
35365625Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle.Nat Commun2022
35360896Finding Correspondence between Metabolomic Features in Untargeted Liquid Chromatography-Mass Spectrometry Metabolomics Datasets.Anal Chem2022
35743227Lipidomic Approaches to Study HDL Metabolism in Patients with Central Obesity Diagnosed with Metabolic Syndrome.Int J Mol Sci2022
36269859Metabolome-wide association study on <i>ABCA7</i> indicates a role of ceramide metabolism in Alzheimer's disease.Proc Natl Acad Sci U S A2022
36130657Creatine Deficiency Syndromes: Comparison of Screening Methods and Characterization of Four Novel Intronic Variants.Clin Chim Acta2022
35069242Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics.Front Physiol2022
35279219Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.Clin Epigenetics2022
35057804Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis.BMC Biol2022
32460431Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma.Hepatology2021
33667994Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness.Redox Biol2021
33806953L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI.Metabolites2021
33608305Metabolic phenotyping and cardiovascular disease: an overview of evidence from epidemiological settings.Heart2021
33722690Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression.Mol Metab2021
33772024Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis.Nat Commun2021
34860829Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure.PLoS Biol2021
34911556Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress.BMC Biol2021
34966300<sup>1</sup>H Nuclear Magnetic Resonance: A Future Approach to the Metabolic Profiling of Psychedelics in Human Biofluids?Front Psychiatry2021
34901052β-Hydroxybutyrate Oxidation in Exercise Is Impaired by Low-Carbohydrate and High-Fat Availability.Front Med (Lausanne)2021
34526660Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer.Commun Biol2021
34491199β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery.Elife2021
34562172IonFlow: a galaxy tool for the analysis of ionomics data sets.Metabolomics2021
34477842Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes.Dis Model Mech2021
34650224Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73.Commun Biol2021
34503513Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.BMC Med2021
34065197Vitamin C Cytotoxicity and Its Effects in Redox Homeostasis and Energetic Metabolism in Papillary Thyroid Carcinoma Cell Lines.Antioxidants (Basel)2021
33398876Monitoring apoptosis in intact cells by high-resolution magic angle spinning <sup>1</sup> H NMR spectroscopy.NMR Biomed2021
33414548A cross-platform approach identifies genetic regulators of human metabolism and health.Nat Genet2021
33175138Metabolomic Analysis in Inflammatory Bowel Disease: A Systematic Review.J Crohns Colitis2021
32423144The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds.Int J Mol Sci2020
32086288Inorganic Nitrate Promotes Glucose Uptake and Oxidative Catabolism in White Adipose Tissue Through the XOR-Catalyzed Nitric Oxide Pathway.Diabetes2020
32084343FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.Cell2020
31665391A Combination of Metabolites Predicts Adherence to the Mediterranean Diet Pattern and Its Associations with Insulin Sensitivity and Lipid Homeostasis in the General Population: The Fenland Study, United Kingdom.J Nutr2020
32101665Effects of Germline VHL Deficiency on Growth, Metabolism, and Mitochondria.N Engl J Med2020
31826699Twenty years of metabonomics: so what has metabonomics done for toxicology?Xenobiotica2020
31978345FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.Cell2020
33214680Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.Commun Biol2020
33396723Decrease in Myelin-Associated Lipids Precedes Neuronal Loss and Glial Activation in the CNS of the Sandhoff Mouse as Determined by Metabolomics.Metabolites2020
33103077Downregulation of Keap1 Confers Features of a Fasted Metabolic State.iScience2020
33075304Unnecessary obstacles to COVID-19 mass testing.Lancet2020
33044703Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners.Metabolomics2020
32945898Insulin resistance induced by growth hormone is linked to lipolysis and associated with suppressed pyruvate dehydrogenase activity in skeletal muscle: a 2⿿ÿ⿿2 factorial, randomised, crossover study in human individuals.Diabetologia2020
32646215Consequences of Lipid Remodeling of Adipocyte Membranes Being Functionally Distinct from Lipid Storage in Obesity.J Proteome Res2020
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Collaborators

Co-authored papers 20
Co-authored papers 12
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University of Cambridge
Co-authored papers 9
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University of Turku and Abo Akademi University
Co-authored papers 9
Institute for Inorganic and Analytical Chemistry, Friedrich Schiller University Jena
Co-authored papers 9
Co-authored papers 8
University of California davis
Co-authored papers 8
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 7
Co-authored papers 7
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 6
Institute of Systems, University of Liverpool
Co-authored papers 6
University of Oxford
Co-authored papers 6
Oxford e-Research Centre, University of Oxford
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
Leibniz Institute for Plant Biochemistry
Co-authored papers 4
UK Dementia Research Institute Centre at Imperial College London
Co-authored papers 4
Institute of Pathology, Ludwig-Maximilians-Universitat Munchen
Co-authored papers 4
VTT Technical Research Centre of Finland Ltd
Co-authored papers 4
Co-authored papers 4
Co-authored papers 4
British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge
Co-authored papers 4
Charite - Universitatsmedizin Berlin
Co-authored papers 4
Co-authored papers 4
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