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Author Details

Michal Hammel
Lawrence Berkeley National Laboratory
1981
106
41
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36660822Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410-DNA interaction using small angle X-ray scattering.Nucleic Acids Res2023
37287434Resolving domain positions of cellobiose dehydrogenase by small angle X-ray scattering.FEBS J2023
36948476Impact of non-ionizable lipids and phase mixing methods on structural properties of lipid nanoparticle formulations.Int J Pharm2023
37279108Correlating the Structure and Gene Silencing Activity of Oligonucleotide-Loaded Lipid Nanoparticles Using Small-Angle X-ray Scattering.ACS Nano2023
37462906Process Robustness in Lipid Nanoparticle Production: A Comparison of Microfluidic and Turbulent Jet Mixing.Mol Pharm2023
36849618Structural and biochemical insight into a modular β-1,4-galactan synthase in plants.Nat Plants2023
36641214Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution.Methods Enzymol2023
36322416A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking.Acta Crystallogr D Struct Biol2022
35768504Structural basis for SHOC2 modulation of RAS signalling.Nature2022
35835745A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.Nat Commun2022
36410949Size exclusion chromatography coupled small angle X-ray scattering with tandem multiangle light scattering at the SIBYLS beamline.Methods Enzymol2022
36133441Predictive high-throughput screening of PEGylated lipids in oligonucleotide-loaded lipid nanoparticles for neuronal gene silencing.Nanoscale Adv2022
32966823Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM.Prog Biophys Mol Biol2021
33843452Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein.MAbs2021
35005430Structural arrangement of the VH and VL domains in the COBRAâ¿¢ T-cell engaging single-chain diabody.Antib Ther2021
34759015A Structural Basis for Inhibition of the Complement Initiator Protease C1r by Lyme Disease Spirochetes.J Immunol2021
34127764Albumin in patients with liver disease shows an altered conformation.Commun Biol2021
34181949Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus.J Biol Chem2021
34197805Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.Biophys J2021
34056803X-ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double-strand break repair impacting cell and cancer biology.Protein Sci2021
33197333Heparin-mediated dimerization of follistatin.Exp Biol Med (Maywood)2021
33337499Mechanism of efficient double-strand break repair by a long non-coding RNA.Nucleic Acids Res2021
33330937An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex.Nucleic Acids Res2021
33469584Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein.bioRxiv2021
33035590Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease.Prog Biophys Mol Biol2021
32518228Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling.Nat Commun2020
31925419A key interaction with RPA orients XPA in NER complexes.Nucleic Acids Res2020
31978064Switchable resolution in soft x-ray tomography of single cells.PLoS One2020
33045735Mechanism of efficient double-strand break repair by a long non-coding RNA.Nucleic Acids Res2020
32931615Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments.Angew Chem Int Ed Engl2020
32868887Novel bacterial clade reveals origin of form I Rubisco.Nat Plants2020
32522879Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.Proc Natl Acad Sci U S A2020
31566566Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy.Elife2019
31659895Combined Solution and Crystal Methods Reveal the Electrostatic Tethers That Provide a Flexible Platform for Replication Activities in the Bacteriophage T7 Replisome.Biochemistry2019
31257107Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling.Structure2019
31397669Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.Elife2019
29652265Hydrogen bonds are a primary driving force for de novo protein folding. Corrigendum.Acta Crystallogr D Struct Biol2018
29996104Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein.Cell Rep2018
29731233Conformational Plasticity of the Immunoglobulin Fc Domain in Solution.Structure2018
29605933Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles.Methods Mol Biol2018
28052235Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.Structure2017
28453785Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.Nucleic Acids Res2017
28397397The structural basis for the functional comparability of factor VIII and the long-acting variant recombinant factor VIII Fc fusion protein.J Thromb Haemost2017
29199976Hydrogen bonds are a primary driving force for de novo protein folding.Acta Crystallogr D Struct Biol2017
27539848Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.J Biol Chem2016
27875301An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.J Biol Chem2016
27482541HU multimerization shift controls nucleoid compaction.Sci Adv2016
27151198FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles.Nucleic Acids Res2016
25723165Structural basis for Marburg virus neutralization by a cross-reactive human antibody.Cell2015
24203338High-throughput SAXS for the characterization of biomolecules in solution: a practical approach.Methods Mol Biol2014
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Collaborators

John A Tainer
The University of Texas MD Anderson Cancer Center
Co-authored papers 34
Greg L Hura
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Co-authored papers 19
Susan P Lees-Miller
University of Calgary, 0 Hospital Drive NW
Co-authored papers 12
Shujuan Fang
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Co-authored papers 6
Dina Schneidman-Duhovny
The Hebrew University of Jerusalem
Co-authored papers 6
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 5
Soumya G Remesh
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Daniel Ricklin
Co-authored papers 4
John D Lambris
Co-authored papers 4
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Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers 3
Carolyn A Larabell
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Co-authored papers 3
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University of California San Francisco
Co-authored papers 3
Walter J Chazin
and Center for Structural Biology, Vanderbilt University
Co-authored papers 2
Axel Ekman
National Center for X-ray Tomography
Co-authored papers 2
Paul D Adams
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Tom L Blundell
Heartand Lung Research Institute, University of Cambridge
Co-authored papers 2
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University of Calgary, 0 Hospital Drive NW
Co-authored papers 2
Linda Lee
Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary
Co-authored papers 2
James M Holton
Lawrence Berkeley National Laboratory
Co-authored papers 2
Tsutomu Matsui
Stanford University
Co-authored papers 1
Weidong Cui
Washington University
Co-authored papers 1
Edward H Egelman
University of Virginia
Co-authored papers 1
Oliver Limbo
Co-authored papers 1
Jill Trewhella
The University of Sydney
Co-authored papers 1
Nigel Kirby
College of Biomedical & Life Sciences, Cardiff University
Co-authored papers 1
Gerry McDermott
University of California San Francisco
Co-authored papers 1
Michael W W Adams
University of Georgia
Co-authored papers 1
Benjamin Webb
University of California san francisco
Co-authored papers 1
Hadi Kharrazi
Johns Hopkins School of Public Health
Co-authored papers 1
Chirayu Chokshi
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Release 1.2