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Author Details

J. Martin Brown
Stanford University School of Medicine
1968
330
79
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36647675Correction: Macrophage Exclusion after Radiation Therapy (MERT): A First-in-Human Phase I/II Trial using a CXCR4 Inhibitor in Glioblastoma.Clin Cancer Res2023
33243481In Regard to Song et al.Int J Radiat Oncol Biol Phys2021
33864825In Reply to Song et al, and In Reply to Brown and Carlson.Int J Radiat Oncol Biol Phys2021
33610292In Regard to Nam et al.Int J Radiat Oncol Biol Phys2021
34793735Reflections of the Senior Editors for Biology.Int J Radiat Oncol Biol Phys2021
32473180Radiation Damage to Tumor Vasculature Initiates a Program That Promotes Tumor Recurrences.Int J Radiat Oncol Biol Phys2020
31812931Macrophage exclusion after radiation therapy (MERT): A new and effective way to increase the therapeutic ratio of radiotherapy.Radiother Oncol2020
30529372Beware of Clinical Trials of DNA Repair Inhibitors.Int J Radiat Oncol Biol Phys2019
31537527Macrophage Exclusion after Radiation Therapy (MERT): A First in Human Phase I/II Trial using a CXCR4 Inhibitor in Glioblastoma.Clin Cancer Res2019
31040924Dynamin 2, cell trafficking, and the triple-negative paradox.Oncotarget2019
29726389Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology.Lancet Oncol2018
29859786<sup>18</sup>F-EF5 PET-based Imageable Hypoxia Predicts Local Recurrence in Tumors Treated With Highly Conformal Radiation Therapy.Int J Radiat Oncol Biol Phys2018
29976509The Biology of SBRT: LQ or Something New?Int J Radiat Oncol Biol Phys2018
30371505Dynamin impacts homology-directed repair and breast cancer response to chemotherapy.J Clin Invest2018
28341752The Promise of Targeting Macrophages in Cancer Therapy.Clin Cancer Res2017
26947881Preclinical Data on Efficacy of 10 Drug-Radiation Combinations: Evaluations, Concerns, and Recommendations.Transl Oncol2016
26538619Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization.Neuro Oncol2016
27154913Improving the Predictive Value of Preclinical Studies in Support of Radiotherapy Clinical Trials.Clin Cancer Res2016
26058991High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients.Radiother Oncol2015
26530765In Reply to Rudoltz and Goldwein et al.Int J Radiat Oncol Biol Phys2015
26286478Cell Death Identification in Anticancer Therapy-Letter.Cancer Res2015
26104924Is Equipment Development Stifling Innovation in Radiation Oncology?Int J Radiat Oncol Biol Phys2015
26068491Gastrointestinal Toxicities With Combined Antiangiogenic and Stereotactic Body Radiation Therapy.Int J Radiat Oncol Biol Phys2015
24497508Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.Proc Natl Acad Sci U S A2014
25047738Circulating mouse Flk1+/c-Kit+/CD45- cells function as endothelial progenitors cells (EPCs) and stimulate the growth of human tumor xenografts.Mol Cancer2014
24929172Dose escalation, not ⿿new biology,⿝ can account for the efficacy of stereotactic body radiation therapy with non-small cell lung cancer. In reply to Rao et al.Int J Radiat Oncol Biol Phys2014
24338942Vasculogenesis: a crucial player in the resistance of solid tumours to radiotherapy.Br J Radiol2014
24335554Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats.Neuro Oncol2014
24423923Inhibition of CXCR7 extends survival following irradiation of brain tumours in mice and rats.Br J Cancer2014
24411596The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?Int J Radiat Oncol Biol Phys2014
23517805Dose escalation, not "new biology," can account for the efficacy of stereotactic body radiation therapy with non-small cell lung cancer.Int J Radiat Oncol Biol Phys2013
23882218The irradiated tumor microenvironment: role of tumor-associated macrophages in vascular recovery.Front Physiol2013
22354749Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.Cancer Res2012
22825248R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells.Cell Cycle2012
22317761Imaging tumor sensitivity to a bioreductive prodrug: two for the price of one!Clin Cancer Res2012
22336907Inhibiting homologous recombination for cancer therapy.Cancer Biol Ther2012
21183291Hypofractionation results in reduced tumor cell kill compared to conventional fractionation for tumors with regions of hypoxia.Int J Radiat Oncol Biol Phys2011
21867428Radiation Resistance in Cancer Therapy: meeting summary and research opportunities. Report of an NCI Workshop held September 1-3, 2010.Radiat Res2011
21587260Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas.Br J Cancer2011
21740251Radiation Resistance in Cancer Therapy: Meeting Summary and Research Opportunities: Report of an NCI Workshop held September 1-3, 2010.Radiat Res2011
21646472Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.Cancer Res2011
20404138Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment.Proc Natl Acad Sci U S A2010
20732963Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors.Clin Cancer Res2010
20832663Stereotactic ablative radiotherapy should be combined with a hypoxic cell radiosensitizer.Int J Radiat Oncol Biol Phys2010
20738173Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells.Radiat Res2010
20179352Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.J Clin Invest2010
20167863Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors.Am J Pathol2010
19221886Role of endothelial progenitors and other bone marrow-derived cells in the development of the tumor vasculature.Angiogenesis2009
19366798DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity.Cancer Res2009
19509245Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A.Mol Cancer Ther2009
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Collaborators

Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers 11
Center for Lymphoid Malignancies, Columbia University Medical Center
Co-authored papers 4
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Co-authored papers 4
The Institute of Cancer Research
Co-authored papers 4
PHusis Therapeutics Inc.
Co-authored papers 4
University of Toronto
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
National Cancer Institute
Co-authored papers 2
Stanford University
Co-authored papers 2
Stanford University
Co-authored papers 2
Co-authored papers 2
The University of Sheffield
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Stanford University
Co-authored papers 2
National Institutes of Health
Co-authored papers 1
Dartmouth College, New Hampshire Geisel School of Medicine
Co-authored papers 1
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 1
Vita-Salute San Raffaele University
Co-authored papers 1
MD Anderson Cancer Center
Co-authored papers 1
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 1
Co-authored papers 1
Intermountain Medical Center
Co-authored papers 1
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
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Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
University of Minnesota - Twin Cities
Co-authored papers 1
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 1
University of Oxford
Co-authored papers 1