Author details

Full Name

Steven Hahn

Affiliation

Fred Hutchinson Cancer Center

ORCID

Career Start Year

1983

Papers

102

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37058407	Broad compatibility between yeast UAS elements and core promoters and identification of promoter elements that determine cofactor specificity.	Cell Rep	2023
37546716	Surprising connections between DNA binding and function for the near-complete set of yeast transcription factors.	bioRxiv	2023
36208626	Yeast Mediator facilitates transcription initiation at most promoters via a Tail-independent mechanism.	Mol Cell	2022
33453189	The Role of XPB/Ssl2 dsDNA Translocase Processivity in Transcription Start-site Scanning.	J Mol Biol	2021
33850123	Mediator subunit Med15 dictates the conserved "fuzzy" binding mechanism of yeast transcription activators Gal4 and Gcn4.	Nat Commun	2021
34137374	BET family members Bdf1/2 modulate global transcription initiation and elongation in <i>Saccharomyces cerevisiae</i>.	Elife	2021
32416068	A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning.	Mol Cell	2020
31913117	Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA.	Elife	2020
32946759	A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning.	Mol Cell	2020
29507182	Transcription Activation Domains of the Yeast Factors Met4 and Ino2: Tandem Activation Domains with Properties Similar to the Yeast Gcn4 Activator.	Mol Cell Biol	2018
29932906	SAGA Is a General Cofactor for RNA Polymerase II Transcription.	Mol Cell	2018
30550782	Phase Separation, Protein Disorder, and Enhancer Function.	Cell	2018
30442764	Structure of human TFIID and mechanism of TBP loading onto promoter DNA.	Science	2018
29562181	Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.	Cell Rep	2018
28918900	Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID.	Mol Cell	2017
29106413	TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning.	Nat Struct Mol Biol	2017
29038161	Mechanistic Differences in Transcription Initiation at TATA-Less and TATA-Containing Promoters.	Mol Cell Biol	2017
28918903	SAGA Is a General Cofactor for RNA Polymerase II Transcription.	Mol Cell	2017
27129284	Transcription Start Site Scanning and the Requirement for ATP during Transcription Initiation by RNA Polymerase II.	J Biol Chem	2016
27797823	Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters.	EMBO J	2016
27193677	Structural biology: Snapshots of transcription initiation.	Nature	2016
27381459	Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIH.	Mol Cell Biol	2016
25775526	Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation.	Proc Natl Acad Sci U S A	2015
26340423	Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH.	Mol Cell	2015
24631155	Distinct dendritic cell subsets dictate the fate decision between effector and memory CD8(+) T cell differentiation by a CD24-dependent mechanism.	Immunity	2014
25216679	Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.	EMBO J	2014
25316786	Ellis Englesberg and the discovery of positive control in gene regulation.	Genetics	2014
25122681	A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface.	Proc Natl Acad Sci U S A	2014
25132180	Architecture of the Saccharomyces cerevisiae RNA polymerase I Core Factor complex.	Nat Struct Mol Biol	2014
24865972	Mutations on the DNA binding surface of TBP discriminate between yeast TATA and TATA-less gene transcription.	Mol Cell Biol	2014
22960599	TFIIB-related factors in RNA polymerase I transcription.	Biochim Biophys Acta	2013
24120742	Structural insights into transcription initiation by RNA polymerase II.	Trends Biochem Sci	2013
22067100	An integrated chemical cross-linking and mass spectrometry approach to study protein complex architecture and function.	Mol Cell Proteomics	2012
22751016	Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening.	Nat Struct Mol Biol	2012
22025674	Architecture of the yeast RNA polymerase II open complex and regulation of activity by TFIIF.	Mol Cell Biol	2012
21149579	Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes.	Mol Cell Biol	2011
22084422	Transcriptional regulation in Saccharomyces cerevisiae: transcription factor regulation and function, mechanisms of initiation, and roles of activators and coactivators.	Genetics	2011
22195967	The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.	Mol Cell	2011
21921198	Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors.	Science	2011
20033062	Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex.	EMBO J	2010
20308326	Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains.	Mol Cell Biol	2010
19581288	Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.	Mol Cell Biol	2009
19924201	Structural biology: New beginnings for transcription.	Nature	2009
18381891	Structure-system correlation identifies a gene regulatory Mediator submodule.	Genes Dev	2008
18981477	Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3.	Genes Dev	2008
18535623	Transcriptional regulation. Meeting on regulatory mechanisms in eukaryotic transcription.	EMBO Rep	2008
17392431	Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis.	Proc Natl Acad Sci U S A	2007
17913884	The transcription elongation factor TFIIS is a component of RNA polymerase II preinitiation complexes.	Proc Natl Acad Sci U S A	2007
17632521	The positions of TFIIF and TFIIE in the RNA polymerase II transcription preinitiation complex.	Nat Struct Mol Biol	2007
16819517	A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex.	Nat Struct Mol Biol	2006

1 - 50 of 102

Sascha H Duttke

College of Veterinary Medicine, Washington State University

Career Start Year 2012

Number of shared co-authors 0

Gonzalo Mill??n-Zambrano

Universidad de Sevilla-CSIC-Universidad Pablo de Olavide

Career Start Year 2011

Number of shared co-authors 1

Huiyan Jin

Texas A&M University, College Station

Career Start Year 2011

Number of shared co-authors 1

Tineke L Lenstra

the Netherlands Cancer Institute, Oncode Institute

Career Start Year 2010

Number of shared co-authors 4

Sean E Hanlon

Drew University, National Institutes of Health, Rutgers University New Brunswick, University of North Carolina at Chapel Hill

Career Start Year 2003

Number of shared co-authors 0

Xenia Pe??ate

Universidad de Sevilla

Career Start Year 2003

Number of shared co-authors 0

Hao Li

School of Public Health, Guangdong Medical University

Career Start Year 2002

Number of shared co-authors 1

Guoqing Zhong

University of Toronto

Career Start Year 2000

Number of shared co-authors 2

Michael-Christopher Keogh

EpiCypher Inc.

Career Start Year 1997

Number of shared co-authors 5

Fran??ois Robert

Institut de recherches cliniques de Montreal

Career Start Year 1996

Number of shared co-authors 1

Craig D Kaplan

University of Pittsburgh

Career Start Year 1995

Number of shared co-authors 5

Vishwanath R Iyer

Indian Institute of Technology Bombay

Career Start Year 1995

Number of shared co-authors 0

Minkyu Kim

University of California san francisco

Career Start Year 1995

Number of shared co-authors 3

David A Bushnell

Stanford University

Career Start Year 1994

Number of shared co-authors 3

Timothy R Hughes

University of Toronto

Career Start Year 1992

Number of shared co-authors 1

Sebasti??n Ch??vez

Universidad de Sevilla

Career Start Year 1991

Number of shared co-authors 2

Jesper Q Svejstrup

Panum Institute, University of Copenhagen

Career Start Year 1990

Number of shared co-authors 2

Erin K O'Shea

Howard Hughes Medical Institute

Career Start Year 1989

Number of shared co-authors 1

Ralph E Davis

Stanford University School of Medicine

Career Start Year 1988

Number of shared co-authors 3

Song Tan

Penn State University, University Park

Career Start Year 1988

Number of shared co-authors 1

Francisco J Asturias

University of Colorado Anschutz Medical Campus

Career Start Year 1988

Number of shared co-authors 2

Monika Tsai-Pflugfelder

Friedrich Miescher Institute for Biomedical Research

Career Start Year 1984

Number of shared co-authors 0

James T Kadonaga

University of California

Career Start Year 1983

Number of shared co-authors 3

Yahli Lorch

Stanford University School of Medicine

Career Start Year 1981

Number of shared co-authors 0

Danny Reinberg

HHMI/NYU Langone School of Medicine

Career Start Year 1980

Number of shared co-authors 2

Michael Shales

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Career Start Year 1980

Number of shared co-authors 7

Mary Ann Osley

University of New Mexico Health Sciences Center

Career Start Year 1974

Number of shared co-authors 0

Robert G Roeder

the Rockefeller University

Career Start Year 1969

Number of shared co-authors 6

Jack F Greenblatt

College Street, University of Toronto

Career Start Year 1969

Number of shared co-authors 3

Roger D Kornberg

Stanford University

Career Start Year 1965

Number of shared co-authors 5

row(s) 1 - 30 of 30

Jeffrey A Ranish

Institute for Systems Biology

Co-authored papers 20

Jie Luo

Institute for Systems Biology

Co-authored papers 9

Stephen Buratowski

Harvard Medical School

Co-authored papers 6

David T Auble

University of Virginia

Co-authored papers 4

Ruedi Aebersold

Institute of Molecular Systems Biology, ETH Zurich

Co-authored papers 3

Kevan M Shokat

University of California San Francisco

Co-authored papers 3

Dylan J Taatjes

University of Colorado

Co-authored papers 2

Bong Kim

Institute for Systems Biology

Co-authored papers 2

William Stafford Noble

Co-authored papers 2

Marine Dehecq

Institut Pasteur

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Vishnu Raman

University of Colorado

Co-authored papers 1

Elton T Young

University of Washington

Co-authored papers 1

Dongyan Wang

Guizhou Medical University

Co-authored papers 1

Christopher C Ebmeier

University of Colorado

Co-authored papers 1

David Baker

University of Washington

Co-authored papers 1

George A Kassavetis

Co-authored papers 1

Jimmy K Eng

University of Washington

Co-authored papers 1

Loes A L van de Pasch

University Medical Centre Utrecht, Universiteitsweg

Co-authored papers 1

Riccardo Pellarin

CNRS UMR 5086 and Universite Claude Bernard Lyon 1

Co-authored papers 1

Steven Henikoff

Fred Hutchinson Cancer Center

Co-authored papers 1

Craig L Peterson

Co-authored papers 1

Colin Logie

Radboud Institute for Molecular Science, Radboud University

Co-authored papers 1

Frank C P Holstege

Princess Maxima Center for Pediatric Oncology

Co-authored papers 1

Charles H Greenberg

University of California San Francisco

Co-authored papers 1

Agnes Viale

Memorial Sloan Kettering Cancer Center

Co-authored papers 1

Peter Cimermancic

Verily Life Sciences LLC

Co-authored papers 1

Alexey I Nesvizhskii

University of Michigan ann arbor

Co-authored papers 1

Youngchang Kim

Argonne National Laboratory

Co-authored papers 1

Sake van Wageningen

Oncode Institute, The Netherlands Cancer Institute

Co-authored papers 1

1 - 30

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