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Author Details

Hanno B Richards
Novartis Pharma AG
1995
61
37
PMIDPaper TitleJournal TitlePublished Year
37194094Two-year imaging outcomes from a phase 3 randomized trial of secukinumab in patients with non-radiographic axial spondyloarthritis.Arthritis Res Ther2023
35146532Long-term Safety of Secukinumab Over Five Years in Patients with Moderate-to-severe Plaque Psoriasis, Psoriatic Arthritis and Ankylosing Spondylitis: Update on Integrated Pooled Clinical Trial and Post-marketing Surveillance Data.Acta Derm Venereol2022
32770640Improvement of Signs and Symptoms of Nonradiographic Axial Spondyloarthritis in Patients Treated With Secukinumab: Primary Results of a Randomized, Placebo-Controlled Phase III Study.Arthritis Rheumatol2021
34481517Secukinumab in non-radiographic axial spondyloarthritis: subgroup analysis based on key baseline characteristics from a randomized phase III study, PREVENT.Arthritis Res Ther2021
31957970Secukinumab 150/300 mg Provides Sustained Improvements in the Signs and Symptoms of Active Ankylosing Spondylitis: 3-Year Results from the Phase 3 MEASURE 3 Study.ACR Open Rheumatol2020
31174584Spinal radiographic progression over 2 years in ankylosing spondylitis patients treated with secukinumab: a historical cohort comparison.Arthritis Res Ther2019
29860356Modified stoke ankylosing spondylitis spinal score as an outcome measure to assess the impact of treatment on structural progression in ankylosing spondylitis.Rheumatology (Oxford)2019
29458278Secukinumab after anti-tumour necrosis factor-α therapy: a phase III study in active rheumatoid arthritis.Scand J Rheumatol2018
30121827Efficacy and Safety of Secukinumab 150 mg with and Without Loading Regimen in Ankylosing Spondylitis: 104-week Results from MEASURE 4 Study.Rheumatol Ther2018
27965257Effect of secukinumab on clinical and radiographic outcomes in ankylosing spondylitis: 2-year results from the randomised phase III MEASURE 1 study.Ann Rheum Dis2017
28217871Secukinumab in Active Rheumatoid Arthritis: A Phase III Randomized, Double-Blind, Active Comparator- and Placebo-Controlled Study.Arthritis Rheumatol2017
28235249Secukinumab and Sustained Improvement in Signs and Symptoms of Patients With Active Ankylosing Spondylitis Through Two Years: Results From a Phase III Study.Arthritis Care Res (Hoboken)2017
29435364Secukinumab provides sustained improvements in the signs and symptoms of active ankylosing spondylitis with high retention rate: 3-year results from the phase III trial, MEASURE 2.RMD Open2017
29138986Secukinumab in Active Rheumatoid Arthritis after Anti-TNFα Therapy: A Randomized, Double-Blind Placebo-Controlled Phase 3 Study.Rheumatol Ther2017
27582421Secukinumab efficacy in anti-TNF-naive and anti-TNF-experienced subjects with active ankylosing spondylitis: results from the MEASURE 2 Study.Ann Rheum Dis2017
27014997Brief Report: Secukinumab Provides Significant and Sustained Inhibition of Joint Structural Damage in a Phase III Study of Active Psoriatic Arthritis.Arthritis Rheumatol2016
27390130Effect of Secukinumab on Patient-Reported Outcomes in Patients With Active Ankylosing Spondylitis: A Phase III Randomized Trial (MEASURE 1).Arthritis Rheumatol2016
26834211Efficacy and Safety of Subcutaneous and Intravenous Loading Dose Regimens of Secukinumab in Patients with Active Rheumatoid Arthritis: Results from a Randomized Phase II Study.J Rheumatol2016
26135703Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial.Lancet2015
26422723Secukinumab Inhibition of Interleukin-17A in Patients with Psoriatic Arthritis.N Engl J Med2015
26699169Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis.N Engl J Med2015
24429175One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study.J Rheumatol2014
24330415Secukinumab improves the signs and symptoms of moderate-to-severe plaque psoriasis in subjects with involvement of hands and/or feet: subanalysis of a randomized, double-blind, placebo-controlled, phase 2 dose-ranging study.J Eur Acad Dermatol Venereol2014
22730366Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study.Ann Rheum Dis2013
23106107Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study.Br J Dermatol2013
19144150Increased expression of FcgammaRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus.Arthritis Res Ther2009
18795942Overexpression of interleukin-12 and T helper 1 predominance in lupus nephritis.Clin Exp Immunol2008
17265494Autoantibodies to RNA helicase A: a new serologic marker of early lupus.Arthritis Rheum2007
17968925Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus.Arthritis Rheum2007
16948135Nucleolar staining cannot be used as a screening test for the scleroderma marker anti-RNA polymerase I/III antibodies.Arthritis Rheum2006
16846524Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases.Arthritis Res Ther2006
16890891Urinary biomarkers in lupus nephritis.Autoimmun Rev2006
15698448Circulating endothelial cells are associated with future vascular events in hemodialysis patients.Kidney Int2005
16126984The interplay of chemokines and dendritic cells in the pathogenesis of lupus nephritis.Ann N Y Acad Sci2005
16126005Association of anti-nucleoprotein autoantibodies with upregulation of Type I interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus.Clin Immunol2005
16214093Th1 cytokines in the pathogenesis of lupus nephritis: the role of IL-18.Autoimmun Rev2005
16177126Induction of apoptosis by the hydrocarbon oil pristane: implications for pristane-induced lupus.J Immunol2005
16175928High sensitivity C-reactive protein in systemic lupus erythematosus: relation to disease activity, clinical presentation and implications for cardiovascular risk.Lupus2005
16142863Fatigue in systemic lupus erythematosus: contributions of disease activity, pain, depression, and perceived social support.J Rheumatol2005
15996187Modulation of the immune response in pristane-induced lupus by expression of activation and inhibitory Fc receptors.Clin Exp Immunol2005
15373921Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis.Clin Exp Immunol2004
15596633Diagnostic accuracy for lupus and other systemic autoimmune diseases in the community setting.Arch Intern Med2004
15188361Strong association of a functional polymorphism in the monocyte chemoattractant protein 1 promoter gene with lupus nephritis.Arthritis Rheum2004
12911539Nephritogenic autoantibodies but absence of nephritis in Il-12p35-deficient mice with pristane-induced lupus.Kidney Int2003
12209530Effect of an exogenous trigger on the pathogenesis of lupus in (NZB x NZW)F1 mice.Arthritis Rheum2002
11737591Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane.Kidney Int2001
11678452Titration emulation: a computer-assisted technique that simplifies the quantification of anti-dsDNA antibodies using the Crithidia luciliae assay.Lupus2001
11665978Increased prevalence of autoantibodies to ku antigen in African American versus white patients with systemic lupus erythematosus.Arthritis Rheum2001
11125477B cell subsets in pristane-induced autoimmunity.Curr Top Microbiol Immunol2000
10931159Widespread susceptibility among inbred mouse strains to the induction of lupus autoantibodies by pristane.Clin Exp Immunol2000
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Collaborators

University of Occupational and Environmental Health
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University of Florida
Co-authored papers 9
Beth Israel Deaconess Hospital
Co-authored papers 3
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David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 1
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Co-authored papers 1
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University of Florida, Univerzitet u Sarajevu Medicinski Fakultet
Co-authored papers 1
Necmettin Erbakan University
Co-authored papers 1
University of Colorado Anschutz Medical Campus
Co-authored papers 1