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Author Details

Lude Franke
2003
265
93
PMIDPaper TitleJournal TitlePublished Year
37503126Understanding the genetic complexity of puberty timing across the allele frequency spectrum.medRxiv2023
37706009Long-term resting EEG correlates of repetitive mild traumatic brain injury and loss of consciousness: alterations in alpha-beta power.2023
37780699Sensory functions and their relation to balance metrics: a secondary analysis of the LIMBIC-CENC multicenter cohort.2023
36882394OTTERS: a powerful TWAS framework leveraging summary-level reference data.Nat Commun2023
36865558Integration of <i>Candida albicans</i>-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation.Front Immunol2023
37114804Semi-automatic translation of medicine usage data (in Dutch, free-text) from Lifelines COVID-19 questionnaires to ATC codes.Database (Oxford)2023
36993312Genetic regulation of fetal hemoglobin across global populations.medRxiv2023
35143365Randomized trial of rTMS in traumatic brain injury: improved subjective neurobehavioral symptoms and increases in EEG delta activity.Brain Injury2022
36035246Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations.HGG Adv2022
35701452Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels.Scientific Reports2022
35953856Limited evidence for blood eQTLs in human sexual dimorphism.Genome Med2022
35815475Results of Ring-Testing of a Semifield Study Design to Investigate Potential Impacts of Crop Protection Products on Bumblebees (Hymenoptera, Apidae) and a Proposal of a Potential Test Design.Environmental Toxicology and Chemistry2022
35681050Genetic, parental and lifestyle factors influence telomere length.Communications Biology2022
35672358Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure.Nat Commun2022
33667644Translational insights from single-cell technologies across the cardiovascular disease continuum.Trends in Cardiovascular Medicine2022
34792549Idéfix: identifying accidental sample mix-ups in biobanks using polygenic scores.2022
35031073Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression.Genome Biol2022
34475573Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.Nat Genet2021
32333097Habitual dietary intake of IBD patients differs from population controls: a case-control study.Eur J Nutr2021
34012022Feasibility of predicting allele specific expression from DNA sequencing using machine learning.Sci Rep2021
34229738Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.Genome Biol2021
33737436Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort.BMJ Open2021
33569077Systematic Prioritization of Candidate Genes in Disease Loci Identifies <i>TRAFD1</i> as a Master Regulator of IFNγ Signaling in Celiac Disease.Front Genet2021
33462485Large-scale association analyses identify host factors influencing human gut microbiome composition.Nat Genet2021
32926755Results of 2-Year Ring Testing of a Semifield Study Design to Investigate Potential Impacts of Plant Protection Products on the Solitary Bees Osmia Bicornis and Osmia Cornuta and a Proposal for a Suitable Test Design.Environmental Toxicology and Chemistry2021
33420481DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.Mol Psychiatry2021
34512620Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability.Front Immunol2021
34381240Retraction Note: Detection and replication of epistasis influencing transcription in humans.Nature2021
34381229Phantom epistasis between unlinked loci.Nature2021
34887417Meta-analyses identify DNA methylation associated with kidney function and damage.Nat Commun2021
33067605Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.Nat Metab2020
32251450Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response.PLoS Pathog2020
32363635Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease.Alimentary Pharmacology and Therapeutics2020
32149610The single-cell eQTLGen consortium.Elife2020
33371313Practical Barriers and Facilitators Experienced by Patients, Pharmacists and Physicians to the Implementation of Pharmacogenomic Screening in Dutch Outpatient Hospital Care-An Explorative Pilot Study.Journal of Personalized Medicine2020
32916427An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors.Environ Int2020
32520614Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure.Hypertension2020
30778224Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases.Nature Genetics2019
31727104Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies.Genome Biol2019
30478441A linear mixed-model approach to study multivariate gene-environment interactions.Nat Genet2019
31234833RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting.BMC Biol2019
31123039Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation.Genetics2019
30852652The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus.Hum Genet2019
31253979High-throughput identification of human SNPs affecting regulatory element activity.Nat Genet2019
31253775Improving the diagnostic yield of exome- sequencing by predicting gene-phenotype associations using large-scale gene expression analysis.Nat Commun2019
30944236Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine.Neurology2019
27802154Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease.Gut2018
30218040Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation.Nat Commun2018
29880062Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.Microbiome2018
30442561Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults.EBioMedicine2018
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Erasmus University Medical Center
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University of Oxford
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Harvard T.H. Chan School of Public Health
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Finnish Cardiovascular Research Center-Tampere - FCRCT, Tampere University
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German Research Center for Cardiovascular Disease (DZHK)
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King's College London
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University Medicine Greifswald
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University Medical Center Rotterdam
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Ludwig-Maximilians-Universitat Munchen
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National Institute on Aging, National Institutes of Health
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National Institute on Aging
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