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Author Details

Angela C Hirbe
Washington University School of Medicine and Siteman Cancer Center
1999
80
25
PMIDPaper TitleJournal TitlePublished Year
37993023CSF1 expression in xanthogranulomatous epithelial tumor/keratin-positive giant cell-rich tumor.Hum Pathol2024
36598417Genomic Patterns of Malignant Peripheral Nerve Sheath Tumor (MPNST) Evolution Correlate with Clinical Outcome and Are Detectable in Cell-Free DNA.Cancer Discov2023
38000020CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.Sci Adv2023
37738543Loss of Chromosome 3q Is a Prognostic Marker in Fusion-Negative Rhabdomyosarcoma.JCO Precis Oncol2023
37048645The Midwest Sarcoma Trials Partnership: Bridging Academic and Community Networks in a Collaborative Approach to Sarcoma.J Clin Med2023
37246765Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology.Neuro Oncol2023
37410426CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression.Clin Cancer Res2023
37174084A Retrospective Multi-Institutional Cohort Analysis of Clinical Characteristics and Outcomes in Dedifferentiated Chondrosarcoma.Cancers (Basel)2023
37328781Treatment decisions and the use of MEK inhibitors for children with neurofibromatosis type 1-related plexiform neurofibromas.BMC Cancer2023
36778419CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.bioRxiv2023
36680529Mutations involving TGFB and MAPK may be associated with malignancy in granular cell tumors.Genes Chromosomes Cancer2023
36534754Molecular Characterization of Multifocal Granular Cell Tumors.Am J Surg Pathol2023
36799629MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors.Clin Cancer Res2023
34932916Plexiform neurofibroma: shedding light on the investigational agents in clinical trials.Expert Opin Investig Drugs2022
35343652Pregnancy outcomes related to the treatment of sarcomas with anthracyclines and/or ifosfamide during pregnancy.Cancer Med2022
35759947A Systematic Review of Recent and Ongoing Clinical Trials in Patients With the Neurofibromatoses.Pediatr Neurol2022
36412916Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer.Integr Cancer Ther2022
36360169The Impact of TSC-1 and -2 Mutations on Response to Therapy in Malignant PEComa: A Multicenter Retrospective Analysis.Genes (Basel)2022
36270157Examining patient perspectives on sarcoma surveillance: The Sarcoma Surveillance Survey.Surg Oncol2022
33212492Preferentially Expressed Antigen in Melanoma (PRAME) Expression in Malignant, but Not Benign, Peripheral Nerve Sheath Tumors.J Neuropathol Exp Neurol2021
33766818Interim Analysis of the Phase II Study: Noninferiority Study of Doxorubicin with Upfront Dexrazoxane plus Olaratumab for Advanced or Metastatic Soft-Tissue Sarcoma.Clin Cancer Res2021
33591953Chromosome 8 gain is associated with high-grade transformation in MPNST.JCI Insight2021
34853665Correction: Aberrant ATRX protein expression is associated with poor overall survival in NF1-MPNST.Oncotarget2021
34439323TYK2 in Cancer Metastases: Genomic and Proteomic Discovery.Cancers (Basel)2021
34647023A genetic mouse model with postnatal <i>Nf1</i> and <i>p53</i> loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor.Neurooncol Adv2021
34646430Phase II study of dacarbazine given with modern prophylactic anti-emetics and growth factor support to patients with metastatic, resistant soft tissue, and bone sarcoma.Rare Tumors2021
34464388Cell-free DNA ultra-low-pass whole genome sequencing to distinguish malignant peripheral nerve sheath tumor (MPNST) from its benign precursor lesion: A cross-sectional study.PLoS Med2021
34572896Patterns of Extrapulmonary Metastases in Sarcoma Surveillance.Cancers (Basel)2021
34680895Genetic Characterization, Current Model Systems and Prognostic Stratification in PAX Fusion-Negative vs. PAX Fusion-Positive Rhabdomyosarcoma.Genes (Basel)2021
34321280A Phase I Study of the Combination of Pexidartinib and Sirolimus to Target Tumor-Associated Macrophages in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors.Clin Cancer Res2021
34284255An open-label single-arm phase II study of regorafenib for the treatment of angiosarcoma.Eur J Cancer2021
34050255Phase II study of pazopanib with oral topotecan in patients with metastatic and non-resectable soft tissue and bone sarcomas.Br J Cancer2021
32556562Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases.Virchows Arch2020
32098059Integrative Analysis Identifies Candidate Tumor Microenvironment and Intracellular Signaling Pathways that Define Tumor Heterogeneity in NF1.Genes (Basel)2020
32664595A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas.Cancers (Basel)2020
32712457A phase II study of pazopanib as front-line therapy in patients with non-resectable or metastatic soft-tissue sarcomas who are not candidates for chemotherapy.Eur J Cancer2020
32882803Special Issue: "Genomics and Models of Nerve Sheath Tumors".Genes (Basel)2020
32707689Non-Conventional Treatments for Conventional Chondrosarcoma.Cancers (Basel)2020
32588468Multi-institutional analysis of stereotactic body radiotherapy for sarcoma pulmonary metastases: High rates of local control with favorable toxicity.J Surg Oncol2020
32841989Vascularized Ulnar Transposition and Radioulnoscapholunate Fusion With Volar Locking Plate in a Dorsal Position Following Resection of Giant Cell Tumor of the Distal Radius.Tech Hand Up Extrem Surg2020
32667755Does Advanced Imaging Have a Role in Detecting Local Recurrence of Soft-tissue Sarcoma?Clin Orthop Relat Res2020
32213089Secondary Sarcomas: Biology, Presentation, and Clinical Care.Am Soc Clin Oncol Educ Book2020
32562630Neurofibromatosis type 1-related tumours in paediatrics: an evolving treatment landscape.Lancet Child Adolesc Health2020
32369930Unmasking Intra-tumoral Heterogeneity and Clonal Evolution in NF1-MPNST.Genes (Basel)2020
32252413Genomics of MPNST (GeM) Consortium: Rationale and Study Design for Multi-Omic Characterization of NF1-Associated and Sporadic MPNSTs.Genes (Basel)2020
31113844Arginine Starvation and Docetaxel Induce c-Myc-Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors.Clin Cancer Res2019
32642734Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1.Neurooncol Adv2019
32642731Diagnosis and management of malignant peripheral nerve sheath tumors: Current practice and future perspectives.Neurooncol Adv2019
31427883Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Bevacizumab (SARC016).Sarcoma2019
31538650Understanding a complicated Gal-1.Neuro Oncol2019
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Collaborators

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Co-authored papers 11
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Co-authored papers 2
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Center for Cancer Research, National Cancer Institute
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St Jude Children's Research Hospital
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Harvard Medical School
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