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Author Details

Andreas Brech
Institute for Cancer Research, Oslo University Hospital
1993
119
58
PMIDPaper TitleJournal TitlePublished Year
36111389TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1.FEBS J2023
37523003Vesicle-mediated transport of ALIX and ESCRT-III to the intercellular bridge during cytokinesis.Cell Mol Life Sci2023
37737664The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk.J Immunol2023
37454772Endocytic trafficking of connexins in cancer pathogenesis.Biochim Biophys Acta Mol Basis Dis2023
37285022siRNA screening reveals that SNAP29 contributes to exosome release.Cell Mol Life Sci2023
37139790BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes.Circ Res2023
34793268Adaptation to hypoxia in <i>Drosophila melanogaster</i> requires autophagy.Autophagy2022
36408828Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair.EMBO J2022
35203441Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells.Biomedicines2022
33468622The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy.J Cell Sci2021
33629888Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation.Autophagy2021
34780750Inhibiting autophagy increases the efficacy of low-dose photodynamic therapy.Biochem Pharmacol2021
34109410JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes.J Cell Sci2021
33473217Wetting regulates autophagy of phase-separated compartments and the cytosol.Nature2021
31366282ESCRT-mediated phagophore sealing during mitophagy.Autophagy2020
32059769RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism.Curr Biol2020
31974402Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake.Nat Commun2020
33139578Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles.Proc Natl Acad Sci U S A2020
32601372Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation.Nat Cell Biol2020
32450518Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation.iScience2020
30295124Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation.Autophagy2019
31519908Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.Nat Commun2019
30926605The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress.J Biol Chem2019
30984240The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS.Front Genet2019
30705279Remodeling of secretory lysosomes during education tunes functional potential in NK cells.Nat Commun2019
29316982The tankyrase inhibitor G007-LK inhibits small intestine LGR5<sup>+</sup> stem cell proliferation without altering tissue morphology.Biol Res2018
30050131Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation.Nat Commun2018
29858227Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics.EMBO J2018
30018090Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy.J Cell Biol2018
28067430Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis.Traffic2017
28077876Microenvironmental autophagy promotes tumour growth.Nature2017
28402725Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites.Nucleus2017
29084199Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation.Nat Cell Biol2017
28784290Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance.Biochem Pharmacol2017
28733455The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions.J Cell Sci2017
26754771Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer.Nat Commun2016
27625181Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding.Cell Cycle2016
27438886PIKfyve inhibition increases exosome release and induces secretory autophagy.Cell Mol Life Sci2016
25519911The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells.J Biol Chem2015
26628094Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline.Development2015
26124443Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.Mol Cancer Res2015
26040712Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.Nature2015
25855459Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth.Nature2015
25487411Glomerular Collagen V Codeposition and Hepatic Perisinusoidal Collagen III Accumulation in Canine Collagen Type III Glomerulopathy.Vet Pathol2015
24359945Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis.Methods Enzymol2014
24952935Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells.Clin Ther2014
24589086Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling.Traffic2014
23154468Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.EMBO Rep2013
23916608Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells.Cancer Lett2013
23878278Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation.J Cell Biol2013
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Collaborators

Ioannis P Nezis
University of Warwick
Co-authored papers 7
Kaisa Haglund
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 6
Qian Peng
Second Affiliated Hospital of Nanchang University
Co-authored papers 3
Vladimir Kirkin
the Institute of Cancer Research London
Co-authored papers 2
Ivan Dikic
Institute of Biochemistry II, Goethe University Frankfurt
Co-authored papers 2
Nikolai Engedal
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 2
Daniela Hoeller
Institute of Biochemistry II, Goethe University
Co-authored papers 1
Nikolai V Gorbunov
Armed Forces Radiobiology Research Institute
Co-authored papers 1
J. Wade Harper
Harvard Medical School
Co-authored papers 1
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 1
Rainer Heuchel
Karolinska Institutet
Co-authored papers 1
Wei-Chiang Shen
Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences
Co-authored papers 1
David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 1
Jahn M Nesland
The Norwegian Radium Hospital, Oslo University Hospital
Co-authored papers 1
Thomas J Begley
University at Albany
Co-authored papers 1
Markku Saari
Co-authored papers 1
Birgit Stein
Co-authored papers 1
Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 1
Marina Londo??o
Gunma University Graduate School of Medicine
Co-authored papers 1
Sara Cherry
University of Pennsylvania
Co-authored papers 1
Peter Jedlicka
Justus Liebig University Giessen
Co-authored papers 1
Svetlana Dokudovskaya
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
Co-authored papers 1
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 1
Karin Przyklenk
Co-authored papers 1
Christopher R McMaster
Dalhousie University
Co-authored papers 1
Mirko H H Schmidt
Institute of Anatomy, Technische Universitat Dresden School of Medicine
Co-authored papers 1
Masashi Narita
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Scott J Bultman
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
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University of Southern Denmark
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Release 1.2