Skip to Main Content

Author Details

Michael W Jakowec
Keck School of Medicine, University of Southern California
1985
78
34
PMIDPaper TitleJournal TitlePublished Year
37855955Increased perivascular space volume in white matter and basal ganglia is associated with cognition in Parkinson's Disease.Brain Imaging Behav2024
37306809Exercise alters cortico-basal ganglia network metabolic connectivity: a mesoscopic level analysis informed by anatomic parcellation defined in the mouse brain connectome.Brain Struct Funct2023
34822124Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning.Mol Neurobiol2022
35442197Promoting Physical Activity in a Spanish-Speaking Latina Population of Low Socioeconomic Status With Chronic Neurological Disorders: Proof-of-Concept Study.JMIR Form Res2022
35594442Magnetic resonance spectroscopy shows associations between neurometabolite levels and perivascular space volume in Parkinson's disease: a pilot and feasibility study.Neuroreport2022
36518341A mind in motion: Exercise improves cognitive flexibility, impulsivity and alters dopamine receptor gene expression in a Parkinsonian rat model.Curr Res Neurobiol2022
36191358Physical activity intensity is associated with cognition and functional connectivity in Parkinson's disease.Parkinsonism Relat Disord2022
33470460Global and Regional Changes in Perivascular Space in Idiopathic and Familial Parkinson's Disease.Mov Disord2021
33629362Exogenous l-lactate promotes astrocyte plasticity but is not sufficient for enhancing striatal synaptogenesis or motor behavior in mice.J Neurosci Res2021
33819900Thalamic volume mediates associations between cardiorespiratory fitness (VO<sub>2</sub>max) and cognition in Parkinson's disease.Parkinsonism Relat Disord2021
34868875The Effects of Cardiorespiratory and Motor Skill Fitness on Intrinsic Functional Connectivity of Neural Networks in Individuals with Parkinson's Disease.Brain Plast2021
34334776Cognition and motor learning in a Parkinson's disease cohort: importance of recall in episodic memory.Neuroreport2021
32668263The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease.Behav Brain Res2020
31778667Treadmill exercise rescues mitochondrial function and motor behavior in the CAG<sub>140</sub> knock-in mouse model of Huntington's disease.Chem Biol Interact2020
31894601Mild cognitive impairment, psychiatric symptoms, and executive functioning in patients with Parkinson's disease.Int J Geriatr Psychiatry2020
32881776Cognitive flexibility deficits in rats with dorsomedial striatal 6-hydroxydopamine lesions tested using a three-choice serial reaction time task with reversal learning.Neuroreport2020
31045849Intensive treadmill exercise increases expression of hypoxia-inducible factor 1α and its downstream transcript targets: a potential role in neuroplasticity.Neuroreport2019
31175682Exercise induces region-specific remodeling of astrocyte morphology and reactive astrocyte gene expression patterns in male mice.J Neurosci Res2019
31396053Dopamine Receptor Blockade Attenuates Purinergic P2X4 Receptor-Mediated Prepulse Inhibition Deficits and Underlying Molecular Mechanisms.Front Cell Neurosci2019
29477921Reduced expression of purinergic P2X4 receptors increases voluntary ethanol intake in C57BL/6J mice.Alcohol2018
29500584Preclinical evaluation of avermectins as novel therapeutic agents for alcohol use disorders.Psychopharmacology (Berl)2018
27641072Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder.Neuropharmacology2017
28502806Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG<sub>140</sub> knock-in mouse model of Huntington's disease.Neurobiol Dis2017
29270905The Oxygen Paradox, the French Paradox, and age-related diseases.Geroscience2017
28877102Treadmill exercise modifies dopamine receptor expression in the prefrontal cortex of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of Parkinson's disease.Neuroreport2017
27082842Evidence of functional brain reorganization on the basis of blood flow changes in the CAG140 knock-in mouse model of Huntington's disease.Neuroreport2016
28149392Engaging cognitive circuits to promote motor recovery in degenerative disorders. exercise as a learning modality.J Hum Kinet2016
27402173Role of purinergic P2X4 receptors in regulating striatal dopamine homeostasis and dependent behaviors.J Neurochem2016
26512345The Effects of Exercise on Dopamine Neurotransmission in Parkinson's Disease: Targeting Neuroplasticity to Modulate Basal Ganglia Circuitry.Brain Plast2015
24316165Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.Neurobiol Dis2014
25009459P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders.Front Neurosci2014
23266798'Roid rage in rats? Testosterone effects on aggressive motivation, impulsivity and tyrosine hydroxylase.Physiol Behav2013
24278239Functional reorganization of motor and limbic circuits after exercise training in a rat model of bilateral parkinsonism.PLoS One2013
24062721The Enemy within: Propagation of Aberrant Corticostriatal Learning to Cortical Function in Parkinson's Disease.Front Neurol2013
23918451Exercise modifies α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor expression in striatopallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse.J Neurosci Res2013
23636255Treadmill exercise elevates striatal dopamine D2 receptor binding potential in patients with early Parkinson's disease.Neuroreport2013
23604007Sociocommunicative and sensorimotor impairments in male P2X4-deficient mice.Neuropsychopharmacology2013
23769598Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease.Lancet Neurol2013
22554779Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat.Neuroscience2012
20730800Acute and long-term response of dopamine nigrostriatal synapses to a single, low-dose episode of 3-nitropropionic acid-mediated chemical hypoxia.Synapse2011
23805167The role of exercise in facilitating basal ganglia function in Parkinson's disease.Neurodegener Dis Manag2011
21765998MPTP Neurotoxicity and Testosterone Induce Dendritic Remodeling of Striatal Medium Spiny Neurons in the C57Bl/6 Mouse.Parkinsons Dis2011
19746427Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.J Neurosci Res2010
20960487Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [¹⁸F]fallypride.Mov Disord2010
20472000Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse.Behav Brain Res2010
20187247Enhancing neuroplasticity in the basal ganglia: the role of exercise in Parkinson's disease.Mov Disord2010
20347863Sex differences in motor behavior in the MPTP mouse model of Parkinson's disease.Pharmacol Biochem Behav2010
18534554The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease.Arch Phys Med Rehabil2008
18718537Memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.Neurobiol Dis2008
18799690Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia.J Neurosci2008
  • 1 - 50 of 78

Recommended Authors

Department of Psychiatry and McLean Hospital, Harvard Medical School
Career Start Year 2014
Number of shared co-authors 1
Neurodegenerative Diseases Research Unit
Career Start Year 2006
Number of shared co-authors 0
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai
Career Start Year 2005
Number of shared co-authors 0
Sean M. Healey & AMG Center for ALS at Mass General
Career Start Year 2003
Number of shared co-authors 0
College of Animal Science and Technology, Huazhong Agricultural University
Career Start Year 2002
Number of shared co-authors 0
Vall d'Hebron Research Institute (VHIR)
Career Start Year 2000
Number of shared co-authors 0
Center for Bionano Intelligence Education and Research, Hanyang University
Career Start Year 1995
Number of shared co-authors 1
University of Leicester
Career Start Year 1992
Number of shared co-authors 0
Weill Cornell Medical College
Career Start Year 1991
Number of shared co-authors 1
University of Wisconsin-Madison
Career Start Year 1990
Number of shared co-authors 0
Louisiana State University Health Sciences Center
Career Start Year 1990
Number of shared co-authors 0
J. David Gladstone Institutes
Career Start Year 1988
Number of shared co-authors 0
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Career Start Year 1988
Number of shared co-authors 0
Novartis Institutes for Biomedical Research
Career Start Year 1986
Number of shared co-authors 0
John Van Geest Center for Brain Repair, University of Cambridge
Career Start Year 1986
Number of shared co-authors 0
National Institute On Aging
Career Start Year 1986
Number of shared co-authors 1
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Career Start Year 1986
Number of shared co-authors 0
University of Florida College of Medicine
Career Start Year 1985
Number of shared co-authors 0
Boston University Chobanian & Avedisian School of Medicine
Career Start Year 1985
Number of shared co-authors 3
University of Brescia
Career Start Year 1985
Number of shared co-authors 0
University of Florida
Career Start Year 1985
Number of shared co-authors 0
National Institute of Environmental Health Sciences
Career Start Year 1983
Number of shared co-authors 0
Johns Hopkins University School of Medicine
Career Start Year 1983
Number of shared co-authors 0
McGovern Medical School at UTHealth
Career Start Year 1982
Number of shared co-authors 0
ASU-Banner Neurodegenerative Disease Research Center, Arizona State University
Career Start Year 1981
Number of shared co-authors 0
Emory University School of Medicine
Career Start Year 1981
Number of shared co-authors 3
Icahn School of Medicine at Mount Sinai
Career Start Year 1980
Number of shared co-authors 0
Inc. University Avenue
Career Start Year 1980
Number of shared co-authors 0
University of Alabama at Birmingham
Career Start Year 1977
Number of shared co-authors 1
Karolinska Institutet
Career Start Year 1968
Number of shared co-authors 0

Collaborators

Keck School of Medicine, University of Southern California
Co-authored papers 54
University of Southern California
Co-authored papers 13
University of Southern California
Co-authored papers 12
The University of California-Berkeley
Co-authored papers 7
University of Virginia
Co-authored papers 5
Istituto di Ricerche Farmacologiche Mario Negri
Co-authored papers 3
Keck School of Medicine University of Southern California
Co-authored papers 2
Keck School of Medicine of USC
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Southern California
Co-authored papers 2
The University of Sydney
Co-authored papers 2
Massachusetts General Hospital
Co-authored papers 2
Co-authored papers 2
Preclinical Imaging, University of California-Irvine
Co-authored papers 1
Stanford University School of Medicine, Stanford University
Co-authored papers 1
Stanford University School of Medicine
Co-authored papers 1
Keio University School of Medicine
Co-authored papers 1
University of Southern California
Co-authored papers 1
Oregon Health & Science University.
Co-authored papers 1
Co-authored papers 1