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Author Details

Michael H Glickman
Technion-Israel Institute of Technology
1995
100
48
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36446979Isolation of Proteasome-Trapped Peptides (PTPs) for Degradome Analysis.Methods Mol Biol2023
37739965Altered ubiquitin signaling induces Alzheimer's disease-like hallmarks in a three-dimensional human neural cell culture model.Nat Commun2023
36979414A Role for the Proteasome Alpha2 Subunit N-Tail in Substrate Processing.Biomolecules2023
37075976Alzheimer's disease-associated mutant ubiquitin (UBB<sup>+1</sup>) is secreted through an autophagosome-like vesicle-mediated unconventional pathway.Biochim Biophys Acta Gene Regul Mech2023
37201526Ubiquitin-independent proteasomal degradation driven by C-degron pathways.Mol Cell2023
35956818Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1.Molecules2022
35764457Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15).Semin Cell Dev Biol2022
34175667Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia.Redox Biol2021
33729481Proteasome in action: substrate degradation by the 26S proteasome.Biochem Soc Trans2021
33498876Structural Insights into Substrate Recognition and Processing by the 20S Proteasome.Biomolecules2021
34528945Synthesis and delivery of a stable phosphorylated ubiquitin probe to study ubiquitin conjugation in mitophagy.Chem Commun (Camb)2021
34702852The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.Nat Commun2021
32882436Inhibition of proteasome reveals basal mitochondrial ubiquitination.J Proteomics2020
33136379On-Demand Detachment of Succinimides on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins.J Am Chem Soc2020
33207558Ubiquitination of Intramitochondrial Proteins: Implications for Metabolic Adaptability.Biomolecules2020
30508698Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status.Redox Biol2019
31487956The Proteasome Lid Triggers COP9 Signalosome Activity during the Transition of <i>Saccharomyces cerevisiae</i> Cells into Quiescence.Biomolecules2019
30792173Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations.Mol Cell2019
29153505Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway.Structure2017
28330605Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit.Cell Chem Biol2017
27477512UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.Cell2016
27698474Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.Nat Commun2016
27613031Studying Protein Ubiquitylation in Yeast.Methods Mol Biol2016
27605452Tuning the proteasome to brighten the end of the journey.Am J Physiol Cell Physiol2016
27960333Synthetic Uncleavable Ubiquitinated Proteins Dissect Proteasome Deubiquitination and Degradation, and Highlight Distinctive Fate of Tetraubiquitin.J Am Chem Soc2016
25389291Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.J Biol Chem2015
26182356Base-CP proteasome can serve as a platform for stepwise lid formation.Biosci Rep2015
25919710The protein quality control machinery regulates its misassembled proteasome subunits.PLoS Genet2015
25829361Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases.Chemistry2015
25703377DNA-damage-inducible 1 protein (Ddi1) contains an uncharacteristic ubiquitin-like domain that binds ubiquitin.Structure2015
24703696Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.Cell Metab2014
24997605Extended ubiquitin species are protein-based DUB inhibitors.Nat Chem Biol2014
24857655Reversible 26S proteasome disassembly upon mitochondrial stress.Cell Rep2014
23562397Mixed-linkage ubiquitin chains send mixed messages.Structure2013
23982732Blm10 facilitates nuclear import of proteasome core particles.EMBO J2013
23665229Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.Mol Cell2013
21820014Proteasomal AAA-ATPases: structure and function.Biochim Biophys Acta2012
23227337Ubiquitin proteasome system in stress and disease.Biochem Res Int2012
23105008Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system.Mol Cell Proteomics2012
22748923Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.Mol Cell2012
22318722Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome.J Biol Chem2012
22405010The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain as a closed toroid of two concentric α-helical rings.Structure2012
22081111Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria.EMBO J2012
20674813Ubiquitin-proteasome system and mitochondria - reciprocity.Biochim Biophys Acta2011
21789183Catalytic and non-catalytic roles for the mono-ADP-ribosyltransferase Arr in the mycobacterial DNA damage response.PLoS One2011
21743439Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry.EMBO J2011
21289101Nuclear import of an intact preassembled proteasome particle.Mol Biol Cell2011
21289098Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome.Mol Biol Cell2011
21389348Proteasome activator 200: the heat is on...Mol Cell Proteomics2011
21427232A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.Mol Cell Proteomics2011
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Collaborators

Noa Reis
Technion-Israel Institute of Technology
Co-authored papers 17
David Fushman
University of Maryland, College Park
Co-authored papers 11
Elah Pick
University of Haifa
Co-authored papers 8
Teresa Rinaldi
Department of Biology and Biotechnologies "C. Darwin", Sapienza University of Rome
Co-authored papers 5
Zanlin Yu
University of California at San Francisco
Co-authored papers 5
Steven P Gygi
Harvard Medical School
Co-authored papers 4
Allan M Weissman
Center for Cancer Research, National Institutes of Health
Co-authored papers 3
Carlos A Casta??eda
Syracuse University, USA Bioinspired Institute
Co-authored papers 3
Laylan Bramasole
Research Center Borstel/Leibniz Lung Center
Co-authored papers 2
Yao Cong
University of Chinese Academy of Sciences
Co-authored papers 2
Wolfgang Baumeister
Max Planck Institute of Biochemistry
Co-authored papers 2
Abhishek Sinha
Oncode Institute, Leiden University Medical Center
Co-authored papers 2
Lewis E Kay
University of Toronto
Co-authored papers 1
Huib Ovaa
Leiden University Medical Center
Co-authored papers 1
Timothy A Lewis
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
Yien Che Tsai
Center for Cancer Research, National Institutes of Health
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Alasdair C Steven
National Institutes of Health
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Meytal Radzinski
Alexander Silberman Institute of Life Science, The Hebrew University of Jerusalem
Co-authored papers 1
Thibault Mayor
Co-authored papers 1
Soyeon Park
Co-authored papers 1
Farid El Oualid
The Netherlands Cancer Institute
Co-authored papers 1
Stephen J Elledge
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Clare Johnson
College of Life Sciences, University of Dundee
Co-authored papers 1
S Gurevich
Technion-Israel Institute of Technology
Co-authored papers 1
David Jimenez-Morales
J. David Gladstone Institutes
Co-authored papers 1
Eran Gefen
University of Haifa-Oranim
Co-authored papers 1
Yuval Klein
University of Haifa at Oranim
Co-authored papers 1
Dana Reichmann
The A. Silberman Institute of Life Sciences, The Hebrew University of Jerusalem
Co-authored papers 1
Release 1.2