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Author Details

Lingshu Wang
National Institute of Allergy and Infectious Disease, National Institute of Health
2003
81
38
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36347257Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.Cell Host Microbe2023
37756379A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.Sci Transl Med2023
37553406Self-assembling SARS-CoV-2 spike-HBsAg nanoparticles elicit potent and durable neutralizing antibody responses via genetic delivery.NPJ Vaccines2023
37986823Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates.bioRxiv2023
37766115Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes.Vaccines (Basel)2023
37321165Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses.Cell Host Microbe2023
37196074EV-D68 virus-like particle vaccines elicit cross-clade neutralizing antibodies that inhibit infection and block dissemination.Sci Adv2023
37395646Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity.J Virol2023
36087785Identification and functional analysis of histone 1.2-like in red sea bream (Pagrus major).Dev Comp Immunol2023
33972947LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.bioRxiv2022
35841885Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.Structure2022
35441178Broadly neutralizing antibodies target the coronavirus fusion peptide.bioRxiv2022
35378757Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.bioRxiv2022
35568025LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.Cell Rep2022
35447072mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron.Cell2022
36517467Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.Nat Commun2022
36516269A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates.Sci Transl Med2022
34921774Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung.Cell2022
35081298SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination.N Engl J Med2022
35324257Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.Science2022
34135892Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.Front Immunol2021
33494381Newcastle Disease Virus-Like Particles Displaying Prefusion-Stabilized SARS-CoV-2 Spikes Elicit Potent Neutralizing Responses.Vaccines (Basel)2021
33655252Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.bioRxiv2021
33907752Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates.bioRxiv2021
33823129Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.Immunity2021
33791692Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects.bioRxiv2021
33821267Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants.bioRxiv2021
33820835The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.Sci Transl Med2021
33732238Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients.Front Immunol2021
34931200Booster of mRNA-1273 Strengthens SARS-CoV-2 Omicron Neutralization.medRxiv2021
34529476Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates.Science2021
34672695Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine-boosted nonhuman primates.Science2021
34729558Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway.bioRxiv2021
34519517Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.Sci Transl Med2021
34461095SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicity.J Biol Chem2021
34426813Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates.bioRxiv2021
34210892Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.Science2021
34237283Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.Cell Rep2021
34031659Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants.bioRxiv2021
32384116Characterization of a human monoclonal antibody generated from a B-cell specific for a prefusion-stabilized spike protein of Middle East respiratory syndrome coronavirus.PLoS One2020
31801868Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.J Virol2020
33024963LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection.bioRxiv2020
33097791A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spike alone.Sci Rep2020
33091382Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.Cell Rep2020
32577634SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness.bioRxiv2020
32596696Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.bioRxiv2020
32877670Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation.Cell Rep2020
32676596A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spike Alone.bioRxiv2020
32619441Convergent Evolution in Breadth of Two V<sub>H</sub>6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.Cell Host Microbe2020
32756549SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.Nature2020
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Collaborators

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Zuckerman Mind Brain Behaviour Institute
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Vanderbilt University Medical Center
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Center for Infectious Diseases Research, Walter Reed Army Institute of Research
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