Author details

Full Name

Vladimir A Kuznetsov

Affiliation

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37094040	Stable bulged G-quadruplexes in the human genome: identification, experimental validation and functionalization.		2023
34967509	ABI1-based expression signature predicts breast cancer metastasis and survival.	Molecular Oncology	2022
35886011	Identification of Recurrent Chromosome Breaks Underlying Structural Rearrangements in Mammary Cancer Cell Lines.	Genes	2022
36688938	A Double Jeopardy: Loss of FMRP Results in DSB and Down-regulated DNA Repair.		2022
33761342	Replication stress induces global chromosome breakage in the fragile X genome.	Cell Reports	2021
34179096	A Tale of Loops and Tails: The Role of Intrinsically Disordered Protein Regions in R-Loop Recognition and Phase Separation.	Frontiers in Molecular Biosciences	2021
34202278	Immunity Depletion, Telomere Imbalance, and Cancer-Associated Metabolism Pathway Aberrations in Intestinal Mucosa upon Short-Term Caloric Restriction.	Cancers	2021
32861256	Defining hypogonadism in male partners of couples with unexplained infertility.	Canadian Journal of Urology	2020
31530281	Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling.	Cell Commun Signal	2019
29775430	Gene expression profile analysis of aortic vascular smooth muscle cells reveals upregulation of cadherin genes in myocardial infarction patients.	Physiol Genomics	2018
30062203	Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in AcuteÂ Myocardial Infarction.	JACC Basic Transl Sci	2018
29876469	Transcriptome alterations of vascular smooth muscle cells in aortic wall of myocardial infarction patients.	Data Brief	2018
30054525	Complementary intestinal mucosa and microbiota responses to caloric restriction.	Scientific Reports	2018
30053183	Toward predictive R-loop computational biology: genome-scale prediction of R-loops reveals their association with complex promoter structures, G-quadruplexes and transcriptionally active enhancers.	Nucleic Acids Research	2018
29945198	Toward predictive R-loop computational biology: genome-scale prediction of R-loops reveals their association with complex promoter structures, G-quadruplexes and transcriptionally active enhancers.	Nucleic Acids Research	2018
29395098	Distinctive molecular signature and activated signaling pathways in aortic smooth muscle cells of patients with myocardial infarction.	Atherosclerosis	2018
29117471	Tumor-adjacent tissue co-expression profile analysis reveals pro-oncogenic ribosomal gene signature for prognosis of resectable hepatocellular carcinoma.	Molecular Oncology	2018
28251929	Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification.	Proc Natl Acad Sci U S A	2017
28724991	Benchmarking selected computational gene network growing tools in context of virus-host interactions.	Scientific Reports	2017
28984201	Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets.	BMC Genomics	2017
28849563	Mathematical Modeling of Avidity Distribution and Estimating General Binding Properties of Transcription Factors from Genome-Wide Binding Profiles.	Methods in Molecular Biology	2017
29030469	Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons.	Genome Research	2017
28827448	EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis.	Journal of Experimental Medicine	2017
27899586	R-loopDB: a database for R-loop forming sequences (RLFS) and R-loops.	Nucleic Acids Research	2017
27819294	Big genomics and clinical data analytics strategies for precision cancer prognosis.	Scientific Reports	2016
27229533	Big data and computational biology strategy for personalized prognosis.	Oncotarget	2016
26100469	Multiple signatures of a disease in potential biomarker space: Getting the signatures consensus and identification of novel biomarkers.	BMC Genomics	2015
25883153	QmRLFS-finder: a model, web server and stand-alone tool for prediction and analysis of R-loop forming sequences.	Nucleic Acids Research	2015
25324314	The TTSMI database: a catalog of triplex target DNA sites associated with genes and regulatory elements in the human genome.	Nucleic Acids Research	2015
25958397	Duplex stem-loop-containing quadruplex motifs in the human genome: a combined genomic and structural study.	Nucleic Acids Research	2015
26232338	Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma.	Gynecologic Oncology	2015
26400173	QmRLFS-finder: a model, web server and stand-alone tool for prediction and analysis of R-loop forming sequences.	Nucleic Acids Research	2015
26517092	Sense-antisense gene-pairs in breast cancer and associated pathological pathways.	Oncotarget	2015
26474389	Genome and transcriptome delineation of two major oncogenic pathways governing invasive ductal breast cancer development.	Oncotarget	2015
26024509	Contrasting expression patterns of coding and noncoding parts of the human genome upon oxidative stress.	Sci Rep	2015
26279757	DLAT subunit of the pyruvate dehydrogenase complex is upregulated in gastric cancer-implications in cancer therapy.	American Journal of Translational Research (discontinued)	2015
24879340	Identification of two poorly prognosed ovarian carcinoma subtypes associated with CHEK2 germ-line mutation and non-CHEK2 somatic mutation gene signatures.	Cell Cycle	2014
25522241	HOXD-AS1 is a novel lncRNA encoded in HOXD cluster and a marker of neuroblastoma progression revealed via integrative analysis of noncoding transcriptome.	BMC Genomics	2014
23825028	Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical subclasses in high-grade serous ovarian carcinoma.	International Journal of Cancer	2014
25825654	How bioinformatics influences health informatics: usage of biomolecular sequences, expression profiles and automated microscopic image analyses for clinical needs and public health.	Health Information Science and Systems	2013
22121227	Quantitative model of R-loop forming structures reveals a novel level of RNA-DNA interactome complexity.	Nucleic Acids Research	2012
22308434	Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors.	Proc Natl Acad Sci U S A	2012
22921398	Targeting glioma stem cells by functional inhibition of a prosurvival oncomiR-138 in malignant gliomas.	Cell Rep	2012
22987071	p53-Independent regulation of p21Waf1/Cip1 expression and senescence by PRMT6.	Nucleic Acids Res	2012
22369099	A robust tool for discriminative analysis and feature selection in paired samples impacts the identification of the genes essential for reprogramming lung tissue to adenocarcinoma.	BMC Genomics	2011
22369587	Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles.	BMC Genomics	2011
19906709	Integrative analysis of the human cis-antisense gene pairs, miRNAs and their transcription regulation patterns.	Nucleic Acids Research	2010
20158880	Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression.	BMC Genomics	2010
20158877	Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alpha.	BMC Genomics	2010
20158875	Projection of gene-protein networks to the functional space of the proteome and its application to analysis of organism complexity.	BMC Genomics	2010