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Author Details

Mark F Bear
Picower Institute for Learning and Memory, Massachusetts Institute of Technology
1980
200
90
PMIDPaper TitleJournal TitlePublished Year
36166713Partial Recovery of Amblyopia After Fellow Eye Ischemic Optic Neuropathy.J Neuroophthalmol2023
37714707Electrophysiological Signatures of Visual Recognition Memory across All Layers of Mouse V1.J Neurosci2023
37795183Human deprivation amblyopia: treatment insights from animal models.Front Neurosci2023
37139534Comparative analysis of structural modifications induced by monocular retinal inactivation and monocular deprivation in the developing cat lateral geniculate nucleus.J Comp Neurol2023
37293080Recovery from Amblyopia in Adulthood: A Meta-Analysis.medRxiv2023
36747661Electrophysiological signatures of visual recognition memory across all layers of mouse V1.bioRxiv2023
35173586Stimulus-Selective Response Plasticity in Primary Visual Cortex: Progress and Puzzles.Front Neural Circuits2022
36094025Metaplasticity: a key to visual recovery from amblyopia in adulthood?Curr Opin Ophthalmol2022
32606374Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice.Mol Psychiatry2021
33833081The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation.J Neurosci2021
34464258Correction of amblyopia in cats and mice after the critical period.Elife2021
34658956mGluR5 Negative Modulators for Fragile X: Treatment Resistance and Persistence.Front Psychiatry2021
34103358Visual Recognition Is Heralded by Shifts in Local Field Potential Oscillations and Inhibitory Networks in Primary Visual Cortex.J Neurosci2021
34314678The spatiotemporal organization of experience dictates hippocampal involvement in primary visual cortical plasticity.Curr Biol2021
34233180Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain.Cell Rep2021
32434848Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome.Sci Transl Med2020
31832634Distinct Laminar Requirements for NMDA Receptors in Experience-Dependent Visual Cortical Plasticity.Cereb Cortex2020
32009901Opposing Somatic and Dendritic Expression of Stimulus-Selective Response Plasticity in Mouse Primary Visual Cortex.Front Cell Neurosci2020
31940718Dynamic Changes in the Bridging Collaterals of the Basal Ganglia Circuitry Control Stress-Related Behaviors in Mice.Mol Cells2020
33232692Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics.Cell2020
31142675Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome.Sci Transl Med2019
29217836Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome.Nat Rev Drug Discov2018
30205056The mouse as a model for neuropsychiatric drug development.Curr Biol2018
30108129Interneuron Simplification and Loss of Structural Plasticity As Markers of Aging-Related Functional Decline.J Neurosci2018
30593282In memoriam: John Lisman - commentaries on CaMKII as a memory molecule.Mol Brain2018
28984295R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice.Neuropsychopharmacology2018
29023717Recovery from the anatomical effects of long-term monocular deprivation in cat lateral geniculate nucleus.J Comp Neurol2018
27748740Arbaclofen in Children and Adolescents with Autism Spectrum Disorder: A Randomized, Controlled, Phase 2 Trial.Neuropsychopharmacology2017
28329674β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X.Cell Rep2017
28951447Experience-Dependent Synaptic Plasticity in V1 Occurs without Microglial CX3CR1.J Neurosci2017
28616094Arbaclofen in fragile X syndrome: results of phase 3 trials.J Neurodev Disord2017
28790183Arc restores juvenile plasticity in adult mouse visual cortex.Proc Natl Acad Sci U S A2017
26943618Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity.Elife2016
27881780Negative Allosteric Modulation of mGluR5 Partially Corrects Pathophysiology in a Mouse Model of Rett Syndrome.J Neurosci2016
27856748Rapid recovery from the effects of early monocular deprivation is enabled by temporary inactivation of the retinas.Proc Natl Acad Sci U S A2016
25599221Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1.Nat Neurosci2015
26243794Conserved hippocampal cellular pathophysiology but distinct behavioural deficits in a new rat model of FXS.Hum Mol Genet2015
26558778Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice.J Neurosci2015
26417096Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex.Proc Natl Acad Sci U S A2015
26697163Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures.Mol Autism2015
26151761Visual recognition memory: a view from V1.Curr Opin Neurobiol2015
26007217Erratum: Visual recognition memory, manifested as long-term habituation, requires synaptic plasticity in V1.Nat Neurosci2015
25429119Microchip amplifier for in vitro, in vivo, and automated whole cell patch-clamp recording.J Neurophysiol2015
25581360Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion.Nat Neurosci2015
24272415STX209 (arbaclofen) for autism spectrum disorders: an 8-week open-label study.J Autism Dev Disord2014
25225298Higher brain functions served by the lowly rodent primary visual cortex.Learn Mem2014
24564913Divergent dysregulation of gene expression in murine models of fragile X syndrome and tuberous sclerosis.Mol Autism2014
24684608Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice.Genes Brain Behav2014
24657967Learned spatiotemporal sequence recognition and prediction in primary visual cortex.Nat Neurosci2014
23352161Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.Neuron2013
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Collaborators

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Ionis Pharmaceuticals Inc
Co-authored papers 4
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Co-authored papers 3
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Co-authored papers 2
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Boston Children's Hospital, Seoul National University, Seoul National University Hospital
Co-authored papers 2
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Harvard Medical School
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Harvard Medical School
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Renaissance School of Medicine, Stony Brook University
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Eva Loth
King's College London
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Duke University School of Medicine
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Howard Colman
Huntsman Cancer Institute, University of Utah
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Robert B Innis
National Institute of Mental Health
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Hongkui Zeng
Allen Institute for Brain Science
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Beth Stevens
Co-authored papers 1
Nathan Palmer
Harvard Medical School
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Linmarie Sikich
Duke University
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David G Amaral
University of California
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Howard Eichenbaum
Boston University.
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Aaron J Bell
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Release 1.2