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Author Details

Nicholas A Graham
University of Southern California
2004
44
21
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37226094Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing.BMC Bioinformatics2023
37161045Functional and phosphoproteomic analysis of β-adrenergic receptor signaling at excitatory synapses in the CA1 region of the ventral hippocampus.Sci Rep2023
34838998Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics.Metab Eng2022
35841827Phospho-proteomics reveals that RSK signaling is required for proliferation of natural killer cells stimulated with IL-2 or IL-15.Cytokine2022
35394425Endogenous <i>Syngap1</i> alpha splice forms promote cognitive function and seizure protection.Elife2022
35365706Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time.Sci Rep2022
35872306The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology.Mol Metab2022
36251711Kinetic and data-driven modeling of pancreatic β-cell central carbon metabolism and insulin secretion.PLoS Comput Biol2022
35216682Glutamine-dependent signaling controls pluripotent stem cell fate.Dev Cell2022
35194942Metabolomics paves the way for improved drug target identification.Mol Syst Biol2022
32692836Differential Gene Set Enrichment Analysis: a statistical approach to quantify the relative enrichment of two gene sets.Bioinformatics2021
33872312The landscape of metabolic pathway dependencies in cancer cell lines.PLoS Comput Biol2021
33564769Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection.bioRxiv2021
34637314Identification of a Proteomic Signature of Senescence in Primary Human Mammary Epithelial Cells.J Proteome Res2021
34453000Bayesian metamodeling of complex biological systems across varying representations.Proc Natl Acad Sci U S A2021
33473109MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis.Nat Commun2021
32429667Improved Discrimination of Asymmetric and Symmetric Arginine Dimethylation by Optimization of the Normalized Collision Energy in Liquid Chromatography-Mass Spectrometry Proteomics.J Proteome Res2020
31914417A synthetic lethal drug combination mimics glucose deprivation-induced cancer cell death in the presence of glucose.J Biol Chem2020
32094265AKT but not MYC promotes reactive oxygen species-mediated cell death in oxidative culture.J Cell Sci2020
32325032Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis.Cell Metab2020
31138644Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells.J Biol Chem2019
31695805Quantitative Proteomics and Metabolomics Reveal Biomarkers of Disease as Potential Immunotherapy Targets and Indicators of Therapeutic Efficacy.Theranostics2019
29961565Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.Biol Psychiatry2019
31451547Deep Protein Methylation Profiling by Combined Chemical and Immunoaffinity Approaches Reveals Novel PRMT1 Targets.Mol Cell Proteomics2019
30197180Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics.Biophys J2018
30124664Phosphopeptide Enrichment Coupled with Label-free Quantitative Mass Spectrometry to Investigate the Phosphoproteome in Prostate Cancer.J Vis Exp2018
28812580Lactate dehydrogenase activity drives hair follicle stem cell activation.Nat Cell Biol2017
28202506Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures.Mol Syst Biol2017
26876179MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.Cell Rep2016
27499020Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer.Cell2016
26175416DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.Cancer Cell2015
24703700Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication.Cell Metab2014
24828528Complexity of metastasis-associated SDF-1 ligand signaling in breast cancer stem cells.Proc Natl Acad Sci U S A2014
24248375Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets.Proc Natl Acad Sci U S A2013
22307624Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression.Proc Natl Acad Sci U S A2012
22735335Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death.Mol Syst Biol2012
22693252BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy.Cancer Res2012
20631065A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.Cancer Res2010
20842061The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy.J Immunother2010
19192266Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex.Neural Dev2009
19549816Tunable interplay between epidermal growth factor and cell-cell contact governs the spatial dynamics of epithelial growth.Proc Natl Acad Sci U S A2009
19271353Automated quantitative analysis of epithelial cell scatter.Cell Adh Migr2008
17507638A microtiter assay for quantifying protein-protein interactions associated with cell-cell adhesion.J Biomol Screen2007
15026412Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed mammary epithelial cells.J Biol Chem2004
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Collaborators

Dongqing Zheng
University of Southern California
Co-authored papers 6
Owen N Witte
University of California los angeles
Co-authored papers 4
Heather R Christofk
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 4
Antoni Ribas
University of California Los Angeles (university of california los angeles)
Co-authored papers 3
Jiaoti Huang
Duke University School of Medicine
Co-authored papers 3
Ajay A Vashisht
David Geffen School of Medicine, University of California los angeles
Co-authored papers 2
Siavash K Kurdistani
David Geffen School of Medicine, University of California los angeles
Co-authored papers 2
James A Wohlschlegel
David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 2
Paul S Mischel
Stanford University
Co-authored papers 2
Bjoern Titz
university of california los angeles
Co-authored papers 2
Kala Bharath
University of California san francisco
Co-authored papers 1
Raymond C Stevens
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Johanna Ten Hoeve
California Nanosystems Institute, University of California los angeles
Co-authored papers 1
Kate L White
Lawrence Berkeley National Laboratory
Co-authored papers 1
Yulia Newton
University of California, Santa Cruz Genomics Institute
Co-authored papers 1
Jihui Zhao
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Vladislav Uzunangelov
University of California
Co-authored papers 1
Chenxi Wang
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Oleg V Evgrafov
Co-authored papers 1
Tanmoy Sanyal
University of California san francisco
Co-authored papers 1
Andrew S Goldstein
University of California los angeles
Co-authored papers 1
Robert F Hevner
university of california san diego School of Medicine, University of California
Co-authored papers 1
Liping Sun
iHuman Institute, ShanghaiTech University
Co-authored papers 1
Joshua M Stuart
University of California at Santa Cruz
Co-authored papers 1
Hsian-Rong Tseng
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 1
Frank McCormick
Frederick National Laboratory for Cancer Research
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Justin K Ichida
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Release 1.2