Author details

Full Name

Maike Sander

Affiliation

ORCID

Career Start Year

1992

Papers

119

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37040771	Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes.	Dev Cell	2023
37407581	Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding.	Cell Death Dis	2023
37028408	Matters arising: Insufficient evidence that pancreatic Î² cells are derived from adult ductal Neurog3-expressing progenitors.	Cell Stem Cell	2023
36711922	Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes.	bioRxiv	2023
36940317	Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.	Diabetes	2023
37116182	Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448.	Diabetes	2023
37231096	Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.	Nat Genet	2023
34823065	Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.	Mol Metab	2022
35953581	Every islet matters: improving the impact of human islet research.	Nature Metabolism	2022
36162056	Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.	Diabetes	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
36778047	Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.	Cell Genom	2022
37078927	Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.	Pancreas	2022
35288669	Sizing up beta cells made from stem cells.	Nat Biotechnol	2022
34416394	What is a Î² cell? - Chapter I in the Human Islet Research Network (HIRN) review series.	Mol Metab	2021
35381060	Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent.		2021
34012112	Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.	Nature	2021
33795864	Single-cell chromatin accessibility identifies pancreatic islet cell type- and state-specific regulatory programs of diabetes risk.	Nat Genet	2021
33509077	Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data.	BMC Genomics	2021
33505025	Systematic analysis of binding of transcription factors to noncoding variants.	Nature	2021
34030925	Transcriptional mechanisms of pancreatic Î²-cell maturation and functional adaptation.	Trends Endocrinol Metab	2021
34131046	Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent.	Diabetes Care	2021
34083580	Transformation of SOX9 cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.	Scientific Reports	2021
34404938	A multi-omics roadmap of Î²-cell failure in type 2 diabetes mellitus.	Nature Reviews Endocrinology	2021
34789845	Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation.	Communications Biology	2021
34789735	Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.	Nat Commun	2021
34663987	Mutations and variants of ONECUT1 in diabetes.	Nat Med	2021
32744504	A human ESC-based screen identifies a role for the translated lncRNA <i>LINC00261</i> in pancreatic endocrine differentiation.	Elife	2020
32179733	PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response.	Cell Death and Disease	2020
32350257	LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.	Nat Commun	2020
31310834	Differential Cell Susceptibilities to Kras<sup>G12D</sup> in the Setting of Obstructive Chronic Pancreatitis.	Cell Mol Gastroenterol Hepatol	2019
31733514	A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells.	iScience	2019
31676735	Human stem cell models: lessons for pancreatic development and disease.	Genes and Development	2019
31807701	In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids.	Science advances	2019
29363536	Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma.	Gut	2019
31475380	Nomenclature for cellular plasticity: are the terms as plastic as the cells themselves?	EMBO Journal	2019
31064983	Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk.	Nat Commun	2019
31362031	Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1Î² is associated with changes in expression of beta-cell maturity genes and associated histone modifications.	Mol Cell Endocrinol	2019
29532564	ETV5 regulates ductal morphogenesis with Sox9 and is critical for regeneration from pancreatitis.	Developmental Dynamics	2018
30361701	Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon<sup>+</sup> Î±-cells.	Nat Cell Biol	2018
30398401	Evaluation of Different Decellularization Protocols on the Generation of Pancreas-Derived Hydrogels.	Tissue Eng Part C Methods	2018
30392959	N<sup>6</sup>-methyladenine DNA Modification in Glioblastoma.	Cell	2018
30194315	Pancreatic Exocrine Tissue Architecture and Integrity are Maintained by E-cadherin During Postnatal Development.	Scientific Reports	2018
30237160	Epigenetics and Epigenomics: Implications for Diabetes and Obesity.	Diabetes	2018
30517875	Integrated InÂ Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic Î² Cell Function.	Cell Rep	2018
29273451	Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice.	Gastroenterology	2018
27941246	LIM domain-binding 1 maintains the terminally differentiated state of pancreatic Î² cells.	J Clin Invest	2017
28467932	Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal Î² Cell Proliferation.	Cell Metab	2017
28951823	Interrogating islets in health and disease with single-cell technologies.	Molecular Metabolism	2017
27694741	Advances in Î² cell replacement and regeneration strategies for treating diabetes.	Journal of Clinical Investigation	2016