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Author Details

Yan Shen
Center for Trauma and Acute Care Surgery Research, Clinical Services Group
1991
244
40
PMIDPaper TitleJournal TitlePublished Year
36112785Low Prevalence but High Impact of COVID-19 Positive Status in Adult Trauma Patients: A Multi-institutional Analysis of 28 904 Patients.Am Surg2023
37089717Analysis of Risk Factors and Protective Strategies for Tube Blockage in Patients with Drug-Induced Liver Failure Based on Artificial Liver Therapy.Evid Based Complement Alternat Med2023
37316990Incidence, outcomes and costs of severe sepsis and septic shock in geriatric trauma patients: Analysis of 2,563,463 hospitalizations at 3,284 hospitals.J Trauma Acute Care Surg2023
36974338WNT16b promotes the proliferation and self-renewal of human limbal epithelial stem/progenitor cells via activating the calcium/calcineurin A/NFATC2 pathway.Cell Prolif2023
36653910Variation in hospice use among trauma centers may impact analysis of geriatric trauma outcomes: An analysis of 1,961,228 Centers for Medicare and Medicaid Services hospitalizations from 2,317 facilities.J Trauma Acute Care Surg2023
36912770Comparative analysis of prevalence, evaluation, management, and rehabilitation outcome of spontaneous isolated visceral artery dissection: a systematic review and meta-analysis of 80 reports.Int J Surg2023
36769811Effect of Hypochlorous Acid on Blepharitis through Ultrasonic Atomization: A Randomized Clinical Trial.J Clin Med2023
36330687The burden of geriatric traumatic brain injury on trauma systems: Analysis of 348,800 Medicare inpatient claims.J Am Geriatr Soc2023
36328853Findings on Repeat Posttraumatic Brain Computed Tomography Scans in Older Patients With Minimal Head Trauma and the Impact of Existing Antithrombotic Use.Ann Emerg Med2023
34292112Quercetin attenuates ischemia reperfusion injury by protecting the blood-brain barrier through Sirt1 in MCAO rats.J Asian Nat Prod Res2022
35504528Discontinuation of atorvastatin use in hospital is associated with increased risk of mortality in COVID-19 patients.J Hosp Med2022
35858494Single nucleotide mutation changes the capability of CCN3 in osteosarcoma cell invasion and differentiation.Transl Oncol2022
35858435Elevated <i>BICD2</i> DNA methylation in blood of major depressive disorder patients and reduction of depressive-like behaviors in hippocampal <i>Bicd2</i>-knockdown mice.Proc Natl Acad Sci U S A2022
36269633Bacteremia in Trauma: A Contemporary Analysis of Blood Culture Results and Outcomes in 158,884 Patients.Surg Infect (Larchmt)2022
36384733Diagnosis and genetic analysis of a case with Bardet-Biedl syndrome caused by compound heterozygous mutations in the BBS12 gene.Yi Chuan2022
34758400The histone deacetylase inhibitor belinostat ameliorates experimental autoimmune encephalomyelitis in mice by inhibiting TLR2/MyD88 and HDAC3/ NF-κB p65-mediated neuroinflammation.Pharmacol Res2022
33242652Antibiotic-induced microbiome depletion in adult mice disrupts blood-brain barrier and facilitates brain infiltration of monocytes after bone-marrow transplantation.Brain Behav Immun2021
34836959Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice.Nat Commun2021
33962999Hijacking Dorsal Raphe to Improve Metabolism and Depression-Like Behaviors via BDNF Gene Transfer in Mice.Diabetes2021
31523044Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci Regarding Associated Variants across Whites and Han Chinese.J Rheumatol2020
32724478Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity.Theranostics2020
32560940Inverse changes in telomere length between the blood and brain in depressive-like mice.J Affect Disord2020
30423353A cynomolgus monkey model of temporal lobe epilepsy.Brain Res Bull2019
31094067Hepatic progenitor cell activation is induced by the depletion of the gut microbiome in mice.Microbiologyopen2019
31165005BDNF Alleviates Neuroinflammation in the Hippocampus of Type 1 Diabetic Mice via Blocking the Aberrant HMGB1/RAGE/NF-κB Pathway.Aging Dis2019
26732600Deletion of mTOR in Reactive Astrocytes Suppresses Chronic Seizures in a Mouse Model of Temporal Lobe Epilepsy.Mol Neurobiol2017
28582515Decreased Prostaglandin D2 Levels in Major Depressive Disorder Are Associated with Depression-Like Behaviors.Int J Neuropsychopharmacol2017
27789685hnRNPs and ELAVL1 cooperate with uORFs to inhibit protein translation.Nucleic Acids Res2017
28028152Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy.J Exp Med2017
27940106Intergenic variants may predispose to major depression disorder through regulation of long non-coding RNA expression.Gene2017
26799699Variants in TERT influencing telomere length are associated with paranoid schizophrenia risk.Am J Med Genet B Neuropsychiatr Genet2016
27794540PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration.Hum Mol Genet2016
27874048Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder.Sci Rep2016
27208512Study of the tetraspanin 18 association with schizophrenia in a Han Chinese population.Psychiatry Res2016
27421225The pathogenic mechanism of dysbindin-1B toxic aggregation: BLOC-1 and intercellular vesicle trafficking.Neuroscience2016
25668491Exome sequencing identifies SUCO mutations in mesial temporal lobe epilepsy.Neurosci Lett2015
27462430Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation.Cell Discov2015
26183697Detection of circulating miRNA levels in schizophrenia.Am J Psychiatry2015
26047305An association study of the m6A genes with major depressive disorder in Chinese Han population.J Affect Disord2015
26004688Genetic variants in long non-coding RNA MIAT contribute to risk of paranoid schizophrenia in a Chinese Han population.Schizophr Res2015
25978640A rare co-segregation-mutation in the insulin receptor substrate 1 gene in one Chinese family with ankylosing spondylitis.PLoS One2015
25704251Propagation of dysbindin-1B aggregates: exosome-mediated transmission of neurotoxic deposits.Neuroscience2015
23999872Notch signaling activation promotes seizure activity in temporal lobe epilepsy.Mol Neurobiol2014
25360641[Deep sequencing for cholecystokinin a receptor gene to get loci associated with schizophrenia].Zhongguo Yi Xue Ke Xue Yuan Xue Bao2014
24791797[Relationship between genetic variation of furin gene and hypercholesterolemia and hyper-low-density lipoprotein cholesterolemia in Kazakh general population].Zhongguo Yi Xue Ke Xue Yuan Xue Bao2014
23335491A combined study of genetic association and brain imaging on the DAOA gene in schizophrenia.Am J Med Genet B Neuropsychiatr Genet2013
24382235[Knockdown of proteasome subunit α7 with small interfering RNA inhibits cell proliferation of K562 cell line].Zhongguo Yi Xue Ke Xue Yuan Xue Bao2013
24382233[Expression of growth-associated protein 43 in the hippocampus of mesial temporal lobe epilepsy mouse model].Zhongguo Yi Xue Ke Xue Yuan Xue Bao2013
23817570A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12.Nat Genet2013
23661460CTLA-4 and CD86 genetic variants and haplotypes in patients with rheumatoid arthritis in southeastern China.Genet Mol Res2013
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Collaborators

The Affiliated Brain Hospital of Nanjing Medical University
Co-authored papers 17
Queen's University
Co-authored papers 11
Co-authored papers 10
Yong Loo Lin School of Medicine, National University of Singapore
Co-authored papers 9
Foshan First People's Hospital
Co-authored papers 9
International Academy of Phronesis Medicine
Co-authored papers 7
Peking University Sixth Hospital, Peking University Institute of Mental Health
Co-authored papers 6
Department of Pharmacy, Liyang People's Hospital
Co-authored papers 5
Co-authored papers 4
Center for Statistical Genetics, Columbia University Medical Center
Co-authored papers 3
School of Public Health, Jilin University
Co-authored papers 3
Center for Trauma and Acute Care Surgery Research, Clinical Services Group
Co-authored papers 3
Co-authored papers 2
Co-authored papers 2
University of Utah
Co-authored papers 2
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 2
McGill University
Co-authored papers 2
First Hospital of Xingtai
Co-authored papers 2
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 2
Wellcome Trust Sanger Institute
Co-authored papers 2
Fudan University
Co-authored papers 2
Adaptive Biotechnologies
Co-authored papers 2
23andMe Inc.
Co-authored papers 2
Center for Cerebrovascular Research
Co-authored papers 2
University of Michigan School of Public Health ann arbor
Co-authored papers 2
Beijing Institute of Genomics, Chinese Academy of Sciences
Co-authored papers 2
Co-authored papers 2
Nanfang Hospital and Basic Medical College, Southern Medical University
Co-authored papers 2
McGill University Health Center
Co-authored papers 2
Co-authored papers 2