Skip to Main Content

Author Details

Jeffrey J Saucerman
University of Virginia
2003
79
30
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38063811Differential sensitivity to longitudinal and transverse stretch mediates transcriptional responses in mouse neonatal ventricular myocytes.Am J Physiol Heart Circ Physiol2024
36370475Signaling network model of cardiomyocyte morphological changes in familial cardiomyopathy.J Mol Cell Cardiol2023
35862254Intercellular model predicts mechanisms of inflammation-fibrosis coupling after myocardial infarction.J Physiol2023
37302817Virtual drug screen reveals context-dependent inhibition of cardiomyocyte hypertrophy.Br J Pharmacol2023
37199469Benchmarking of protein interaction databases for integration with manually reconstructed signalling network models.J Physiol2023
37091233Network model integrated with multi-omic data predicts MBNL1 signals that drive myofibroblast activation.iScience2023
36744541Diversity of cells and signals in the cardiovascular system.J Physiol2023
36909540Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts.bioRxiv2023
34798125Computational model of brain endothelial cell signaling pathways predicts therapeutic targets for cerebral pathologies.J Mol Cell Cardiol2022
35372032Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy.Front Oncol2022
35668305Multiscale model of heart growth during pregnancy: integrating mechanical and hormonal signaling.Biomech Model Mechanobiol2022
35369706Inhibition of DYRK1a Enhances Cardiomyocyte Cycling After Myocardial Infarction.Circ Res2022
36522168Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease.Genome Res2022
35082446Brahma safeguards canalization of cardiac mesoderm differentiation.Nature2022
32970240A multiscale model of cardiac concentric hypertrophy incorporating both mechanical and hormonal drivers of growth.Biomech Model Mechanobiol2021
33571402Network model-based screen for FDA-approved drugs affecting cardiac fibrosis.CPT Pharmacometrics Syst Pharmacol2021
33647311Computational models of cardiovascular regulatory mechanisms.J Mol Cell Cardiol2021
33667419Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity.J Mol Cell Cardiol2021
34155901The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.J Am Heart Assoc2021
33408259Network Analysis Reveals a Distinct Axis of Macrophage Activation in Response to Conflicting Inflammatory Cues.J Immunol2021
32209358Computational model predicts paracrine and intracellular drivers of fibroblast phenotype after myocardial infarction.Matrix Biol2020
34195592Mechano-chemo signaling interactions modulate matrix production by cardiac fibroblasts.Matrix Biol Plus2020
33338038Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy.PLoS Comput Biol2020
32448062Quantification of model and data uncertainty in a network analysis of cardiac myocyte mechanosignalling.Philos Trans A Math Phys Eng Sci2020
30597148High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets.J Mol Cell Cardiol2019
31920691Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling.Front Physiol2019
30683889Mechanical regulation of gene expression in cardiac myocytes and fibroblasts.Nat Rev Cardiol2019
30571977Atg2, Atg9 and Atg18 in mitochondrial integrity, cardiac function and healthspan in Drosophila.J Mol Cell Cardiol2019
29352247High content analysis identifies unique morphological features of reprogrammed cardiomyocytes.Sci Rep2018
30030017Network-based predictions of in vivo cardiac hypertrophy.J Mol Cell Cardiol2018
29868933Mapping macrophage polarization over the myocardial infarction time continuum.Basic Res Cardiol2018
29507758A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure.NPJ Syst Biol Appl2018
28590470An engineering design approach to systems biology.Integr Biol (Camb)2017
29131824Predictive model identifies key network regulators of cardiomyocyte mechano-signaling.PLoS Comput Biol2017
28951721Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics.Front Physiol2017
28916822Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy.Nat Commun2017
27017945A computational model of cardiac fibroblast signaling predicts context-dependent drivers of myofibroblast differentiation.J Mol Cell Cardiol2016
26608708Computational modeling of cardiac fibroblasts and fibrosis.J Mol Cell Cardiol2016
27240543Knowledge gaps to understanding cardiac macrophage polarization following myocardial infarction.Biochim Biophys Acta2016
25304353Automated microscopy of cardiac myocyte hypertrophy: a case study on the role of intracellular α-adrenergic receptors.Methods Mol Biol2015
24225179PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-adrenergic signaling.J Mol Cell Cardiol2014
24867460Modeling the effects of β1-adrenergic receptor blockers and polymorphisms on cardiac myocyte Ca2+ handling.Mol Pharmacol2014
24613264Phenotypic screen quantifying differential regulation of cardiac myocyte hypertrophy identifies CITED4 regulation of myocyte elongation.J Mol Cell Cardiol2014
24644293A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo.J Biol Chem2014
24302730Scaffold state switching amplifies, accelerates, and insulates protein kinase C signaling.J Biol Chem2014
24378906Mechanisms of cyclic AMP compartmentation revealed by computational models.J Gen Physiol2014
24052393Integrating fluorescent biosensor data using computational models.Methods Mol Biol2014
23028093Identification and characterization of poly(I:C)-induced molecular responses attenuated by nicotine in mouse macrophages.Mol Pharmacol2013
24634817Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane.Mol Metab2013
24047977Modeling mitochondrial ROS: a great balancing act.Biophys J2013
  • 1 - 50 of 79

Recommended Authors

Toni M West
University of California at Davis
Career Start Year 2013
Number of shared co-authors 0
Jens Hansen
Icahn School of Medicine at Mount Sinai
Career Start Year 2011
Number of shared co-authors 1
James L Engel
David Geffen School of Medicine, University of California los angeles
Career Start Year 2009
Number of shared co-authors 0
Billy Chen
Cedars-Sinai Medical Center
Career Start Year 2005
Number of shared co-authors 0
Li Zhang
Brigham and Women's Hospital and Harvard Medical School
Career Start Year 2003
Number of shared co-authors 0
Egbert Bisping
Medical University of Graz
Career Start Year 2001
Number of shared co-authors 0
David A Liem
University of California davis
Career Start Year 2001
Number of shared co-authors 1
Kevin Bersell
Vanderbilt University
Career Start Year 2001
Number of shared co-authors 0
Arun Padmanabhan
Gladstone Institutes San Francisco
Career Start Year 2001
Number of shared co-authors 4
William M Oldham
Harvard Medical School
Career Start Year 2000
Number of shared co-authors 0
Mohit Jain
Cumming School of Medicine, University of Calgary, 0 Hospital Drive NW
Career Start Year 2000
Number of shared co-authors 0
Matthew T Wheeler
Stanford University School of Medicine
Career Start Year 1999
Number of shared co-authors 0
Julie R McMullen
Baker Heart and Diabetes Institute
Career Start Year 1998
Number of shared co-authors 0
Javier E L??pez
and Cardiovascular Research Institute, University of California davis
Career Start Year 1998
Number of shared co-authors 0
Stephane Heymans
Maastricht University Medical Centre
Career Start Year 1998
Number of shared co-authors 0
Anthony O Gramolini
University of Toronto, University Avenue
Career Start Year 1996
Number of shared co-authors 1
Euan A Ashley
Stanford University
Career Start Year 1993
Number of shared co-authors 0
Reza Ardehali
University of California los angeles
Career Start Year 1993
Number of shared co-authors 0
William R MacLellan
University of Washington
Career Start Year 1993
Number of shared co-authors 1
Jennifer L Hall
Institute for Precision Cardiovascular Medicine
Career Start Year 1992
Number of shared co-authors 0
Peipei Ping
University of California at Los Angeles
Career Start Year 1992
Number of shared co-authors 1
Calum A MacRae
Harvard Medical School and Cardiovascular Division, Brigham and Women's Hospital
Career Start Year 1991
Number of shared co-authors 0
William T Pu
Boston Children's Hospital, Harvard Medical School
Career Start Year 1989
Number of shared co-authors 2
Kenneth B Margulies
Perelman School of Medicine at the University of Pennsylvania
Career Start Year 1988
Number of shared co-authors 0
Burkert Pieske
Charite University Medicine, Berlin Institute of Health (BIH)
Career Start Year 1988
Number of shared co-authors 0
Raimond L Winslow
Johns Hopkins University
Career Start Year 1987
Number of shared co-authors 3
Douglas B Sawyer
Center for Molecular Medicine, Maine Medical Center Research Institute
Career Start Year 1985
Number of shared co-authors 1
Bruce R Conklin
Gladstone Institutes
Career Start Year 1984
Number of shared co-authors 6
Steven R Houser
Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University
Career Start Year 1979
Number of shared co-authors 2
Ravi Iyengar
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Career Start Year 1976
Number of shared co-authors 1

Collaborators

Andrew D McCulloch
University of California
Co-authored papers 11
Jeffrey W Holmes
Co-authored papers 9
Jason H Yang
Rutgers New Jersey Medical School
Co-authored papers 5
Zhen Yan
Co-authored papers 4
Merry L Lindsey
Co-authored papers 4
Donald M Bers
Co-authored papers 4
Jason A Papin
University of Virginia
Co-authored papers 3
Ali Khalilimeybodi
University of Virginia
Co-authored papers 3
Joseph Randall Moorman
Center for Advanced Medical Analytics, University of Virginia School of Medicine
Co-authored papers 2
Karen D Fairchild
University of Virginia
Co-authored papers 2
Stefan Bekiranov
University of Virginia
Co-authored papers 2
Douglas E Lake
University of Virginia School of Medicine
Co-authored papers 2
Jin Zhang
Co-authored papers 2
Christoph D Rau
Co-authored papers 1
Douglas A Lauffenburger
Massachusetts Institute of Technology
Co-authored papers 1
Kevin So
Gladstone Institutes
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Yibin Wang
Co-authored papers 1
Ravi V Desai
Gladstone Institutes
Co-authored papers 1
Jiewei Xu
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 1
Kenneth Walsh
University of Virginia School of Medicine
Co-authored papers 1
Ruth H??ttenhain
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 1
Leor S Weinberger
Gladstone/UCSF Center for Cell Circuitry, Gladstone Institutes
Co-authored papers 1
Kevin M Hu
Gladstone Institutes
Co-authored papers 1
Benjamin J Polacco
Gladstone Institutes
Co-authored papers 1
Tom C Freeman
The Roslin Institute, University of Edinburgh
Co-authored papers 1
Nicholas W Chavkin
University of Virginia School of Medicine
Co-authored papers 1
Austin Hsu
Gladstone Institutes
Co-authored papers 1
James N Weiss
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Kavitha S Rao
Gladstone Institutes
Co-authored papers 1
Release 1.2