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Author Details

Charles Boone
University of Toronto
1979
294
91
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36909656PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data.bioRxiv2023
38045359Single-cell imaging of protein dynamics of paralogs reveals mechanisms of gene retention.bioRxiv2023
37891180N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.Nat Commun2023
36909656PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data.bioRxiv2023
37205480K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ).bioRxiv2023
37201508Reproducibility metrics for context-specific CRISPR screens.Cell Syst2023
37436802Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability.Mol Biol Cell2023
37369212Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity.Cell Chem Biol2023
37115757Overexpression profiling reveals cellular requirements in the context of genetic backgrounds and environments.PLoS Genet2023
37891180N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.Nat Commun2023
38045359Single-cell imaging of protein dynamics of paralogs reveals mechanisms of gene retention.bioRxiv2023
37115757Overexpression profiling reveals cellular requirements in the context of genetic backgrounds and environments.PLoS Genet2023
37205480K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ).bioRxiv2023
37436802Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability.Mol Biol Cell2023
37369212Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity.Cell Chem Biol2023
37201508Reproducibility metrics for context-specific CRISPR screens.Cell Syst2023
34294428Retention of duplicated genes in evolution.Trends Genet2022
35531664High-Throughput Chemical Screen Identifies a 2,5-Disubstituted Pyridine as an Inhibitor of Candida albicans Erg11.mSphere2022
35970996Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux.Nat Chem Biol2022
35587152Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG.G3 (Bethesda)2022
36037231Repression of essential cell cycle genes increases cellular fitness.PLoS Genet2022
35752611Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.Nat Commun2022
36002506Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux.Nat Chem Biol2022
35428529Correction to: Retention of duplicated genes in evolution: (Trends in Genetics, January 2022, Vol. 38, No. 1).Trends Genet2022
36270234Context-dependent regulation of ferroptosis sensitivity.Cell Chem Biol2022
34294428Retention of duplicated genes in evolution.Trends Genet2022
34520745Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.Cell Chem Biol2022
35019680Jerveratrum-Type Steroidal Alkaloids Inhibit β-1,6-Glucan Biosynthesis in Fungal Cell Walls.Microbiol Spectr2022
35087094High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds.NPJ Syst Biol Appl2022
35587152Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG.G3 (Bethesda)2022
35531664High-Throughput Chemical Screen Identifies a 2,5-Disubstituted Pyridine as an Inhibitor of Candida albicans Erg11.mSphere2022
35428529Correction to: Retention of duplicated genes in evolution: (Trends in Genetics, January 2022, Vol. 38, No. 1).Trends Genet2022
35752611Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation.Nat Commun2022
36002506Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux.Nat Chem Biol2022
35970996Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux.Nat Chem Biol2022
36037231Repression of essential cell cycle genes increases cellular fitness.PLoS Genet2022
36270234Context-dependent regulation of ferroptosis sensitivity.Cell Chem Biol2022
35087094High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds.NPJ Syst Biol Appl2022
35019680Jerveratrum-Type Steroidal Alkaloids Inhibit β-1,6-Glucan Biosynthesis in Fungal Cell Walls.Microbiol Spectr2022
34520745Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1.Cell Chem Biol2022
33462440Ï¿-SGA: synthetic genetic array analysis for systematically screening and quantifying trigenic interactions in yeast.Nat Protoc2021
34018332A method for benchmarking genetic screens reveals a predominant mitochondrial bias.Mol Syst Biol2021
33751052Reduced gene dosage of histone H4 prevents CENP-A mislocalization and chromosomal instability in Saccharomyces cerevisiae.Genetics2021
33958448Environmental robustness of the global yeast genetic interaction network.Science2021
33956138Genome-wide screening of genes associated with momilactone B sensitivity in the fission yeast Schizosaccharomyces pombe.G3 (Bethesda)2021
33733368Trigenic Synthetic Genetic Array (Ï¿-SGA) Technique for Complex Interaction Analysis.Methods Mol Biol2021
33462440Ï¿-SGA: synthetic genetic array analysis for systematically screening and quantifying trigenic interactions in yeast.Nat Protoc2021
34096681A genome-scale yeast library with inducible expression of individual genes.Mol Syst Biol2021
34139168Single-cell image analysis to explore cell-to-cell heterogeneity in isogenic populations.Cell Syst2021
34318674Improving Measures of Chemical Structural Similarity Using Machine Learning on Chemical-Genetic Interactions.J Chem Inf Model2021
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Collaborators

University of Toronto
Co-authored papers 108
Co-authored papers 96
University of Minnesota - Twin Cities
Co-authored papers 63
University of Toronto
Co-authored papers 35
University of Toronto, 1 King's College Circle
Co-authored papers 29
University of Toronto
Co-authored papers 15
McGill University
Co-authored papers 15
University of Toronto
Co-authored papers 15
University of Toronto
Co-authored papers 15
Cubist Pharmaceuticals, Inc.
Co-authored papers 15
University of Toronto
Co-authored papers 14
University of Toronto
Co-authored papers 14
Co-authored papers 13
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 12
University of Toronto
Co-authored papers 12
University of Toronto
Co-authored papers 12
University of Toronto
Co-authored papers 10
Blavatnik Institute, Harvard Medical School
Co-authored papers 10
Massachusetts Institute of Technology
Co-authored papers 10
Massachusetts Institute of Technology
Co-authored papers 10
College of Medicine, University of Saskatchewan
Co-authored papers 10
Co-authored papers 10
College Street, University of Toronto
Co-authored papers 9
University of Calgary
Co-authored papers 9
School of Pharmacy, University of Waterloo
Co-authored papers 8
University of California berkeley
Co-authored papers 7
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 7
Columbia University Medical Center
Co-authored papers 7
Boston University School of Medicine, Boston University
Co-authored papers 7
University of California San Francisco
Co-authored papers 7