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Author Details

Lakshman Gunaratnam
Schulich School of Medicine and Dentistry, The University of Western Ontario
2000
54
20
PMIDPaper TitleJournal TitlePublished Year
36931168Outcomes in ANCA-associated vasculitis patients with end-stage kidney disease on renal replacement therapy-A meta-analysis.Semin Arthritis Rheum2023
37247212The effect of late-onset CMV infection on the outcome of renal allograft considering initial graft function.Transpl Infect Dis2023
36448607Impaired Efferocytosis by Synovial Macrophages in Patients With Knee Osteoarthritis.Arthritis Rheumatol2023
36881454Health System-Level Barriers to Living Donor Kidney Transplantation: Protocol for a Comparative Case Study Analysis.JMIR Res Protoc2023
35236716SARS-CoV-2 Vaccine Mandates for Patients on the Kidney Transplant Waitlist: Are They Ethical?Clin J Am Soc Nephrol2022
35636639Defective KIM-1 phagocytosis does not predispose to acute graft dysfunction after kidney transplantation in humans.Kidney Int2022
36545249Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit.Can J Kidney Health Dis2022
36514718The Association of Pre-Transplant C-Peptide Level with the Development of Post-Transplant Diabetes: A Cohort Study.Kidney3602022
32910428Evaluation of left atrial remodeling in kidney transplant patients using cardiac magnetic resonance imaging.J Nephrol2021
35369656Prevalence of Frailty in Patients Referred to the Kidney Transplant Waitlist.Kidney3602021
33891625Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation.PLoS One2021
34926614The Increase in Paraoxonase 1 Is Associated With Decrease in Left Ventricular Volume in Kidney Transplant Recipients.Front Cardiovasc Med2021
34820133A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol.Can J Kidney Health Dis2021
33980499Short-term antibody response after 1 dose of BNT162b2 vaccine in patients receiving hemodialysis.CMAJ2021
34088927Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma.Sci Rep2021
33475872Cardiac MRI assessment of the right ventricle pre-and post-kidney transplant.Int J Cardiovasc Imaging2021
33211259Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site.Mol Cell Biochem2021
32963793Frailty and the Kidney Transplant Wait List: Protocol for a Multicenter Prospective Study.Can J Kidney Health Dis2020
31984793Heterotrimeric Gα<sub>12/13</sub> proteins in kidney injury and disease.Am J Physiol Renal Physiol2020
30904438Patients with immunological diseases or on peritoneal dialysis are prone to false positive flow cytometry crossmatch.Hum Immunol2019
31361994Growth differentiation factor 15 is decreased by kidney transplantation.Clin Biochem2019
29603641Donor kidney injury molecule-1 promotes graft recovery by regulating systemic necroinflammation.Am J Transplant2018
29925521Caspase-3 Is a Pivotal Regulator of Microvascular Rarefaction and Renal Fibrosis after Ischemia-Reperfusion Injury.J Am Soc Nephrol2018
30554567Cardiovascular magnetic resonance left ventricular strain in end-stage renal disease patients after kidney transplantation.J Cardiovasc Magn Reson2018
30542623Determinants of Left Ventricular Characteristics Assessed by Cardiac Magnetic Resonance Imaging and Cardiovascular Biomarkers Related to Kidney Transplantation.Can J Kidney Health Dis2018
29693725Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis.J Cell Physiol2018
26697979G protein α<sub>12</sub> (Gα<sub>12</sub>) is a negative regulator of kidney injury molecule-1-mediated efferocytosis.Am J Physiol Renal Physiol2016
26726878Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice.Nat Med2016
25759266Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury.Am J Pathol2015
26239336Hydrogen Sulfide Treatment Mitigates Renal Allograft Ischemia-Reperfusion Injury during Cold Storage and Improves Early Transplant Kidney Function and Survival Following Allogeneic Renal Transplantation.J Urol2015
25706976Cardiac, renal, and central nervous system dysfunction with eosinophilia: eosinophilic granulomatosis with polyangiitis.Lancet2015
24523388Kidney injury molecule-1 expression in IgA nephropathy and its correlation with hypoxia and tubulointerstitial inflammation.Am J Physiol Renal Physiol2014
24829508Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis.Am J Physiol Renal Physiol2014
24954453Dialysis recovery time: more than just another serum albumin.Am J Kidney Dis2014
23671537Transplant renal artery stenosis secondary to mechanical compression from polycystic kidney disease: A case report.Can Urol Assoc J2013
22676829Localized mandibular enlargement in end-stage renal disease: two case reports and a review of the literature.Oral Surg Oral Med Oral Pathol Oral Radiol2012
18940248Identification of PP2A as a novel interactor and regulator of TRIP-Br1.Cell Signal2009
19152710TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors.J Transl Med2009
19118148HIF in kidney disease and development.J Am Soc Nephrol2009
19052740TGF-alpha as a candidate tumor antigen for renal cell carcinomas.Cancer Immunol Immunother2009
18414680Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells.J Clin Invest2008
18316374CRM1-mediated nuclear export is required for 26 S proteasome-dependent degradation of the TRIP-Br2 proto-oncoprotein.J Biol Chem2008
17670948Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer.Proc Natl Acad Sci U S A2007
17565996Galpha12 stimulates apoptosis in epithelial cells through JNK1-mediated Bcl-2 degradation and up-regulation of IkappaBalpha.J Biol Chem2007
16912185Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17.Cancer Res2006
15958567Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer.Cancer Res2005
16129783Regulation of ubiquitin ligase dynamics by the nucleolus.J Cell Biol2005
15280664Oxygen sensing by H+: implications for HIF and hypoxic cell memory.Cell Cycle2004
15181450HIF activation by pH-dependent nucleolar sequestration of VHL.Nat Cell Biol2004
12595284Increased myofibrillar protein phosphatase-1 activity impairs rat aortic smooth muscle activation after hypoxia.Am J Physiol Heart Circ Physiol2003
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Collaborators

Joseph V Bonventre
Brigham & Women's Hospital
Co-authored papers 7
Ron Wald
University of Toronto
Co-authored papers 4
Amanda J Vinson
Dalhousie University
Co-authored papers 3
Matthew A Weir
Western University
Co-authored papers 2
Bhanu Prasad Venkatesulu
Loyola University, Illinois Edward Hines Veteran Affairs Hospital
Co-authored papers 2
Andrew A House
The Lilibeth Caberto Kidney Clinical Research Unit, Western University
Co-authored papers 2
Colin McKerlie
The Hospital for Sick Children
Co-authored papers 2
Madeleine Moussa
Schulich School of Medicine and Dentistry, University of Western Ontario
Co-authored papers 1
Bruce C Carleton
BC Children's Hospital Research Institute
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Ryan Huang
The Hospital for Sick Children
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Alexandra P Zorzi
Western University
Co-authored papers 1
Marie-Jos??e H??bert
Universite de Montreal
Co-authored papers 1
Michael J Rieder
Schulich School of Medicine and Dentistry, University of Western Ontario
Co-authored papers 1
Giles Lajoie
Schulich School of Medicine & Dentistry, Western University
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Paul C Nathan
The Hospital for Sick Children, University of Toronto
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Sharon Abish
McGill University
Co-authored papers 1
Kent Doi
The University of Tokyo Hospital
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Anshika Jain
University of Toronto
Co-authored papers 1
Cheryl Ho
University of British Columbia
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Michael Brudno
University of Toronto
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Michael Zappitelli
Toronto Hospital for Sick Children, University of Toronto
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Jasmine Lee
New York Institute of Technology College of Osteopathic Medicine
Co-authored papers 1
Yong Jin Lim
Schulich School of Medicine & Dentistry, Western University
Co-authored papers 1
Khosrow Adeli
The Hospital for Sick Children
Co-authored papers 1
Shahrad Rod Rassekh
British Columbia Children's Hospital, The University of British Columbia
Co-authored papers 1
Sushrut S Waikar
Boston University Chobanian & Avedisian School of Medicine, Boston Medical Center
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Sara Kuruvilla
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Release 1.2